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Taking people in United StatesPhase 3

Tests daratumumab added to lenalidomide and dexamethasone in high-risk smoldering myeloma

Tests adding daratumumab to standard drugs in adults with high-risk smoldering myeloma.

Plain-language title generated from the registry record
Registry title: Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

Key facts

Where
Aberdeen, Adrian, Aitkin, Albany, Albert Lea, Allentown, Alma, Alton, American Fork, Ames, Anaconda, Anchorage, Ankeny, Ann Arbor, Appleton, Arroyo Grande, Ashland, Atlanta, Auburn, Aurora, Baker City, Ballwin, Baltimore, Bardstown, Barrington, Baton Rouge, Battle Creek, Baytown, Beavercreek, Bellevue, Bellingham, Belpre, Bend, Bethlehem, Bettendorf, Billings, Birmingham, Bloomington, Boardman, Boiling Springs, Boise, Bolivar, Boone, Boston, Boulder, Bozeman, Brainerd, Branson, Bridgeport, Brighton, Brownstown, Bryan, Burbank, Burien, Burlington, Burnsville, Burr Ridge, Butte, Caldwell, Cambridge, Camden, Camillus, Canton, Cape Girardeau, Carbondale, Carmel, Carmichael, Caro, Carroll, Carson City, Carterville, Carthage, Cedar City, Centennial, Centerville, Centralia, Chapel Hill, Chardon, Charleston, Charlotte, Charlottesville, Chaska, Chelsea, Chesterfield, Cheyenne, Chicago, Chillicothe, Cincinnati, City of Saint Peters, Clackamas, Clarkston, Cleveland, Clinton Township, Clive, Cody, Coeur d'Alene, Colorado Springs, Columbus, Conroe, Coon Rapids, Coos Bay, Corbin, Council Bluffs, Creston, Creve Coeur, Crystal Lake, Cudahy, Dallas, Danville, Dayton, Dearborn, Decatur, Deer River, DeKalb, Delaware, Denver, Derby, Des Moines, Detroit, Detroit Lakes, Dixon, Downers Grove, Dublin, Duluth, Durango, Easley, East China Township, East Stroudsburg, East Syracuse, Eau Claire, Edina, Edmonds, Effingham, Elgin, Elk Grove, Emeryville, Emmett, Englewood, Enumclaw, Eureka, Evanston, Everett, Fairbanks, Fairfield, Fargo, Farmington, Federal Way, Fergus Falls, Findlay, Flint, Fond du Lac, Fort Dodge, Fort Lauderdale, Fort Smith, Fort Worth, Fosston, Franklin, Fridley, Fruitland, Gahanna, Galesburg, Garden City, Geneva, Germantown, Gig Harbor, Glastonbury, Glens Falls, Glenview, Golden, Goodyear, Grafton, Grand Island, Grand Junction, Grand Rapids, Great Bend, Great Falls, Greeley, Green Bay, Greenville, Greenwich, Greenwood, Greer, Grosse Pointe Woods, Grove City, Guilford, Hartford, Harvey, Havre, Hayward, Hazel Crest, Hazleton, Henderson, Hershey, Hibbing, Highland Park, Hillsborough, Homer Glen, Hot Springs, Houston, Indianapolis, Iowa City, Issaquah, Jackson, Jamestown, Janesville, Jefferson, Jefferson City, Johns Creek, Johnson Creek, Joliet, Joplin, Kalamazoo, Kalispell, Kansas City, Kearney, Kenansville, Kennewick, Kenosha, Kettering, Kewanee, Kingman, Kinston, Kirkland, La Crosse, La Jolla, Lacey, Lafayette, Lakewood, Lancaster, Lansing, Las Vegas, League City, Lee's Summit, Lewisburg, Lewistown, Lexington, Libertyville, Lima, Lincoln, Littleton, Livonia, Logan, London, Lone Tree, Longmont, Longview, Louisville, Loveland, Macomb, Madison, Mansfield, Maple Grove, Maplewood, Marietta, Marinette, Marion, Marlette, Marshalltown, Marshfield, Martinez, Martinsburg, Mattoon, Mayfield Heights, Maywood, Melrose Park, Mentor, Merced, Meridian, Middleburg Heights, Midland, Milwaukee, Minneapolis, Minocqua, Missoula, Monroe, Monticello, Morgantown, Morristown, Mount Vernon, Mukwonago, Murray, Muskegon, Nampa, Nashville, Nassau Bay, New Albany, New Haven, New Orleans, New Richmond, New Ulm, New York, Newark, Newberg, Niles, Normal, North Haven, Norton Shores, Novi, O'Fallon, Oak Lawn, Oakland, Oconomowoc, Oconto Falls, Ogden, Oklahoma City, Omaha, Ontario, Orange, Oregon City, Osage Beach, Oshkosh, Oswego, Ottawa, Overland Park, Pahrump, Papillion, Park Rapids, Park Ridge, Parker, Parkersburg, Pekin, Peoria, Perrysburg, Peru, Philadelphia, Phoenix, Pittsburg, Pittsburgh, Pontiac, Port Huron, Port Townsend, Portland, Portsmouth, Post Falls, Pottstown, Pottsville, Poulsbo, Princeton, Provo, Pueblo, Puyallup, Racine, Rancho Mirage, Rapid City, Redmond, Reed City, Reno, Renton, Rice Lake, Richardson, Richlands, Richmond, Riverton, Robbinsdale, Rochester, Rochester Hills, Rocklin, Rolla, Sacramento, Saginaw, Saint Joseph, Saint Louis Park, Saint Paul, Sainte Genevieve, Salinas, Salt Lake City, San Luis Obispo, Sandpoint, Sandstone, Sandusky, Santa Maria, Savannah, Scottsdale, Scranton, Seattle, Sedro-Woolley, Selinsgrove, Seneca, Shakopee, Shawano, Sheboygan, Shelby, Shelton, Shepherdsville, Sheridan, Shreveport, Silverdale, Sioux Falls, Skokie, Southfield, Spokane, Spokane Valley, Spooner, Springfield, St Louis, St. George, Stamford, State College, Sterling Heights, Stevens Point, Stillwater, Stockton, Sturgeon Bay, Sugar Land, Sullivan, Summit, Superior, Syracuse, Tacoma, Tawas City, The Woodlands, Thomasville, Thornton, Toledo, Topeka, Torrington, Traverse City, Troy, Trumbull, Tucson, Tulsa, Twin Falls, Two Rivers, Urbana, Valdosta, Vancouver, Verona, Virginia, Voorhees Township, Waconia, Walla Walla, Walnut Creek, Warren, Warrenville, Washington, Waterbury, Waterford, Waukee, Waukesha, Wauwatosa, West Allis, West Bloomfield, West Branch, West Des Moines, West Reading, Westerly, Westerville, Westlake, Westminster, Weston, Wheat Ridge, Wheeling, Wilkes-Barre, Willmar, Woodbury, Woodland, Wooster, Wyandotte, Wyoming, Yakima, Yelm, York Village, Yorkville, Youngstown, Ypsilanti, and Zanesville, United StatesSee the 742 sites
Phase
Phase 3

Where in United States

  • Providence Regional Cancer System-AberdeenAberdeen, United StatesTaking people
  • Hickman Cancer CenterAdrian, United StatesNo longer taking part
  • Riverwood Healthcare CenterAitkin, United StatesNo longer taking part
  • Phoebe Putney Memorial HospitalAlbany, United StatesTaking people
  • Mayo Clinic Health System in Albert LeaAlbert Lea, United StatesNo longer taking part
  • Lehigh Valley Hospital-Cedar CrestAllentown, United StatesTaking people
  • MyMichigan Medical Center GratiotAlma, United StatesTaking people
  • OSF Saint Anthony's Health CenterAlton, United StatesTaking people
  • American Fork Hospital / Huntsman Intermountain Cancer CenterAmerican Fork, United StatesNo longer taking part
  • Mary Greeley Medical CenterAmes, United StatesNo longer taking part
  • McFarland Clinic - AmesAmes, United StatesNo longer taking part
  • Community Hospital of AnacondaAnaconda, United StatesNo longer taking part
  • Alaska Breast Care and Surgery LLCAnchorage, United StatesTaking people
  • Alaska Oncology and Hematology LLCAnchorage, United StatesTaking people
  • Alaska Women's Cancer CareAnchorage, United StatesTaking people
  • Anchorage Associates in Radiation MedicineAnchorage, United StatesTaking people
  • Katmai Oncology GroupAnchorage, United StatesTaking people
  • Providence Alaska Medical CenterAnchorage, United StatesTaking people
  • Anchorage Oncology CentreAnchorage, United StatesNo longer taking part
  • Anchorage Radiation Therapy CenterAnchorage, United StatesNo longer taking part
  • UI Health Care Mission Cancer and Blood - Ankeny ClinicAnkeny, United StatesTaking people
  • Trinity Health Saint Joseph Mercy Hospital Ann ArborAnn Arbor, United StatesTaking people
  • University of Michigan Rogel Cancer CenterAnn Arbor, United StatesTaking people
  • ThedaCare Regional Cancer CenterAppleton, United StatesTaking people
  • Mission Hope Medical Oncology - Arroyo GrandeArroyo Grande, United StatesTaking people
  • PCR OncologyArroyo Grande, United StatesTaking people
  • Duluth Clinic AshlandAshland, United StatesTaking people
  • Northwest Wisconsin Cancer CenterAshland, United StatesTaking people
  • Emory Saint Joseph's HospitalAtlanta, United StatesTaking people
  • Emory University Hospital MidtownAtlanta, United StatesTaking people
  • Emory University Hospital/Winship Cancer InstituteAtlanta, United StatesTaking people
  • MultiCare Auburn Medical CenterAuburn, United StatesNo longer taking part
  • Advocate Outpatient Center - AuroraAurora, United StatesTaking people
  • Rocky Mountain Cancer Centers-AuroraAurora, United StatesTaking people
  • Rush-Copley Medical CenterAurora, United StatesTaking people
  • The Medical Center of AuroraAurora, United StatesNo longer taking part
  • Saint Alphonsus Cancer Care Center-Baker CityBaker City, United StatesNo longer taking part
  • Mercy Oncology and Hematology - Clayton-ClarksonBallwin, United StatesNo longer taking part
  • Saint Agnes HospitalBaltimore, United StatesTaking people
  • CommonSpirit Saint Joseph Hospital - BardstownBardstown, United StatesNo longer taking part
  • Advocate Good Shepherd HospitalBarrington, United StatesTaking people
  • LSU Health Baton Rouge-North ClinicBaton Rouge, United StatesTaking people
  • Our Lady of The LakeBaton Rouge, United StatesTaking people
  • Our Lady of the Lake Physician GroupBaton Rouge, United StatesTaking people
  • Hematology/Oncology Clinic PLLCBaton Rouge, United StatesNo longer taking part
  • Bronson Battle CreekBattle Creek, United StatesTaking people
  • Houston Methodist San Jacinto HospitalBaytown, United StatesTaking people
  • Indu and Raj Soin Medical CenterBeavercreek, United StatesTaking people
  • Overlake Medical CenterBellevue, United StatesNo longer taking part
  • PeaceHealth Saint Joseph Medical CenterBellingham, United StatesTaking people
  • Strecker Cancer Center-BelpreBelpre, United StatesNo longer taking part
  • Saint Charles Health SystemBend, United StatesTaking people
  • Lehigh Valley Hospital - MuhlenbergBethlehem, United StatesTaking people
  • University of Iowa Healthcare Cancer Services Quad CitiesBettendorf, United StatesTaking people
  • Billings Clinic Cancer CenterBillings, United StatesTaking people
  • Saint Vincent Frontier Cancer CenterBillings, United StatesNo longer taking part
  • Saint Vincent HealthcareBillings, United StatesNo longer taking part
  • University of Alabama at Birmingham Cancer CenterBirmingham, United StatesTaking people
  • Illinois CancerCare-BloomingtonBloomington, United StatesTaking people
  • Saint Elizabeth Boardman HospitalBoardman, United StatesTaking people
  • Prisma Health Cancer Institute - SpartanburgBoiling Springs, United StatesNo longer taking part
  • Saint Alphonsus Cancer Care Center-BoiseBoise, United StatesTaking people
  • Saint Luke's Cancer Institute - BoiseBoise, United StatesTaking people
  • Central Care Cancer Center - BolivarBolivar, United StatesTaking people
  • McFarland Clinic - BooneBoone, United StatesNo longer taking part
  • Tufts Medical CenterBoston, United StatesTaking people
  • Boulder Community Foothills HospitalBoulder, United StatesTaking people
  • Rocky Mountain Cancer Centers-BoulderBoulder, United StatesTaking people
  • Bozeman Health Deaconess HospitalBozeman, United StatesTaking people
  • Essentia Health Saint Joseph's Medical CenterBrainerd, United StatesTaking people
  • Cox Cancer Center BransonBranson, United StatesNo longer taking part
  • United Hospital CenterBridgeport, United StatesTaking people
  • Trinity Health IHA Medical Group Hematology Oncology - BrightonBrighton, United StatesTaking people
  • Trinity Health Medical Center - BrightonBrighton, United StatesTaking people
  • Henry Ford Cancer Institute-DownriverBrownstown, United StatesTaking people
  • Saint Joseph Regional Cancer CenterBryan, United StatesNo longer taking part
  • Providence Saint Joseph Medical Center/Disney Family Cancer CenterBurbank, United StatesTaking people
  • Highline Medical Center-Main CampusBurien, United StatesNo longer taking part
  • Aurora Cancer Care-Southern Lakes VLCCBurlington, United StatesTaking people
  • Minnesota Oncology - BurnsvilleBurnsville, United StatesTaking people
  • Fairview Ridges HospitalBurnsville, United StatesNo longer taking part
  • Loyola Center for Health at Burr RidgeBurr Ridge, United StatesNo longer taking part
  • Saint James Community Hospital and Cancer Treatment CenterButte, United StatesNo longer taking part
  • Saint Alphonsus Cancer Care Center-CaldwellCaldwell, United StatesTaking people
  • Cambridge Medical CenterCambridge, United StatesNo longer taking part
  • Cooper Hospital University Medical CenterCamden, United StatesTaking people
  • Hematology Oncology Associates of CNY at CamillusCamillus, United StatesTaking people
  • Aultman Health FoundationCanton, United StatesTaking people
  • Illinois CancerCare-CantonCanton, United StatesTaking people
  • Trinity Health IHA Medical Group Hematology Oncology - CantonCanton, United StatesTaking people
  • Trinity Health Medical Center - CantonCanton, United StatesTaking people
  • Mercy Cancer Center - Cape GirardeauCape Girardeau, United StatesTaking people
  • Saint Francis Medical CenterCape Girardeau, United StatesTaking people
  • Memorial Hospital of CarbondaleCarbondale, United StatesTaking people
  • IU Health North HospitalCarmel, United StatesNo longer taking part
  • Mercy Cancer Center - CarmichaelCarmichael, United StatesTaking people
  • Mercy San Juan Medical CenterCarmichael, United StatesTaking people
  • Caro Cancer CenterCaro, United StatesNo longer taking part
  • Saint Anthony Regional HospitalCarroll, United StatesTaking people
  • Carson Tahoe Regional Medical CenterCarson City, United StatesNo longer taking part
  • SIH Cancer InstituteCarterville, United StatesTaking people
  • Illinois CancerCare-CarthageCarthage, United StatesTaking people
  • Sandra L Maxwell Cancer CenterCedar City, United StatesNo longer taking part
  • Rocky Mountain Cancer Centers - CentennialCentennial, United StatesNo longer taking part
  • Miami Valley Hospital SouthCenterville, United StatesTaking people
  • Dayton Physicians LLC-Miami Valley SouthCenterville, United StatesNo longer taking part
  • Centralia Oncology ClinicCentralia, United StatesTaking people
  • Providence Regional Cancer System-CentraliaCentralia, United StatesTaking people
  • Saint Mary's HospitalCentralia, United StatesNo longer taking part
  • UNC Lineberger Comprehensive Cancer CenterChapel Hill, United StatesTaking people
  • Geauga HospitalChardon, United StatesTaking people
  • West Virginia University Charleston DivisionCharleston, United StatesTaking people
  • Medical University of South CarolinaCharleston, United StatesNo longer taking part
  • Carolinas Medical Center/Levine Cancer InstituteCharlotte, United StatesNo longer taking part
  • University of Virginia Cancer CenterCharlottesville, United StatesTaking people
  • Minnesota Oncology Hematology PA-ChaskaChaska, United StatesTaking people
  • Chelsea HospitalChelsea, United StatesTaking people
  • Trinity Health IHA Medical Group Hematology Oncology - Chelsea HospitalChelsea, United StatesTaking people
  • Saint Luke's HospitalChesterfield, United StatesTaking people
  • Memorial Hospital of Laramie CountyCheyenne, United StatesTaking people
  • Cheyenne Regional Medical Center-WestCheyenne, United StatesNo longer taking part
  • Advocate Illinois Masonic Medical CenterChicago, United StatesTaking people
  • Swedish Covenant HospitalChicago, United StatesTaking people
  • Adena Regional Medical CenterChillicothe, United StatesTaking people
  • Bethesda North HospitalCincinnati, United StatesTaking people
  • Good Samaritan Hospital - CincinnatiCincinnati, United StatesTaking people
  • Oncology Hematology Care Inc-KenwoodCincinnati, United StatesNo longer taking part
  • TriHealth Cancer Institute-AndersonCincinnati, United StatesNo longer taking part
  • TriHealth Cancer Institute-WestsideCincinnati, United StatesNo longer taking part
  • Siteman Cancer Center at Saint Peters HospitalCity of Saint Peters, United StatesTaking people
  • Clackamas Radiation Oncology CenterClackamas, United StatesTaking people
  • Providence Cancer Institute Clackamas ClinicClackamas, United StatesNo longer taking part
  • Hematology Oncology Consultants-ClarkstonClarkston, United StatesNo longer taking part
  • Newland Medical Associates-ClarkstonClarkston, United StatesNo longer taking part
  • Case Western Reserve UniversityCleveland, United StatesTaking people
  • Cleveland Clinic FoundationCleveland, United StatesTaking people
  • MetroHealth Medical CenterCleveland, United StatesTaking people
  • Henry Ford Macomb Hospital-Clinton TownshipClinton Township, United StatesTaking people
  • Mercy Cancer Center-West LakesClive, United StatesTaking people
  • UI Health Care Mission Cancer and Blood - West Des Moines ClinicClive, United StatesTaking people
  • Billings Clinic-CodyCody, United StatesNo longer taking part
  • Kootenai Health - Coeur d'AleneCoeur d'Alene, United StatesTaking people
  • Penrose-Saint Francis HealthcareColorado Springs, United StatesTaking people
  • Rocky Mountain Cancer Centers-PenroseColorado Springs, United StatesTaking people
  • Saint Francis Cancer CenterColorado Springs, United StatesTaking people
  • Doctors HospitalColumbus, United StatesTaking people
  • Grant Medical CenterColumbus, United StatesTaking people
  • John B Amos Cancer CenterColumbus, United StatesTaking people
  • Mount Carmel East HospitalColumbus, United StatesTaking people
  • Mount Carmel Health Center WestColumbus, United StatesTaking people
  • Riverside Methodist HospitalColumbus, United StatesTaking people
  • The Mark H Zangmeister CenterColumbus, United StatesTaking people
  • Columbus Oncology and Hematology Associates IncColumbus, United StatesNo longer taking part
  • UT MD Anderson - The WoodlandsConroe, United StatesTaking people
  • Mercy HospitalCoon Rapids, United StatesTaking people
  • Minnesota Oncology - Coon RapidsCoon Rapids, United StatesTaking people
  • Bay Area HospitalCoos Bay, United StatesTaking people
  • Commonwealth Cancer Center-CorbinCorbin, United StatesNo longer taking part
  • Alegent Health Mercy HospitalCouncil Bluffs, United StatesNo longer taking part
  • Greater Regional Medical CenterCreston, United StatesTaking people
  • Siteman Cancer Center at West County HospitalCreve Coeur, United StatesTaking people
  • AMG Crystal Lake - OncologyCrystal Lake, United StatesTaking people
  • Aurora Saint Luke's South ShoreCudahy, United StatesTaking people
  • UT Southwestern Simmons Cancer Center - RedBirdDallas, United StatesTaking people
  • UT Southwestern/Simmons Cancer Center-DallasDallas, United StatesTaking people
  • Carle at The RiverfrontDanville, United StatesTaking people
  • Geisinger Medical CenterDanville, United StatesTaking people
  • Dayton Physician LLC - EnglewoodDayton, United StatesTaking people
  • Miami Valley HospitalDayton, United StatesTaking people
  • Miami Valley Hospital NorthDayton, United StatesTaking people
  • Premier Blood and Cancer CenterDayton, United StatesTaking people
  • Dayton Veterans Affairs Medical CenterDayton, United StatesNo longer taking part
  • Good Samaritan Hospital - DaytonDayton, United StatesNo longer taking part
  • Henry Ford Medical Center-FairlaneDearborn, United StatesTaking people
  • Cancer Care Specialists of Illinois - DecaturDecatur, United StatesTaking people
  • Decatur Memorial HospitalDecatur, United StatesTaking people
  • Essentia Health - Deer River ClinicDeer River, United StatesTaking people
  • Northwestern Medicine Cancer Center KishwaukeeDeKalb, United StatesNo longer taking part
  • Delaware Health Center-Grady Cancer CenterDelaware, United StatesTaking people
  • Grady Memorial HospitalDelaware, United StatesTaking people
  • Presbyterian - Saint Lukes Medical Center - Health OneDenver, United StatesTaking people
  • AdventHealth PorterDenver, United StatesNo longer taking part
  • Cancer Center of Colorado at Sloan's LakeDenver, United StatesNo longer taking part
  • Colorado Blood Cancer InstituteDenver, United StatesNo longer taking part
  • National Jewish Health-Main CampusDenver, United StatesNo longer taking part
  • Rocky Mountain Cancer Centers-MidtownDenver, United StatesNo longer taking part
  • Rocky Mountain Cancer Centers-RoseDenver, United StatesNo longer taking part
  • Rose Medical CenterDenver, United StatesNo longer taking part
  • Saint Joseph Hospital - Cancer Centers of ColoradoDenver, United StatesNo longer taking part
  • The Women's Imaging CenterDenver, United StatesNo longer taking part
  • Western Surgical CareDenver, United StatesNo longer taking part
  • Smilow Cancer Hospital-Derby Care CenterDerby, United StatesTaking people
  • Broadlawns Medical CenterDes Moines, United StatesTaking people
  • Iowa Lutheran HospitalDes Moines, United StatesTaking people
  • Iowa Methodist Medical CenterDes Moines, United StatesTaking people
  • Mercy Medical Center - Des MoinesDes Moines, United StatesTaking people
  • UI Health Care Mission Cancer and Blood - Des Moines ClinicDes Moines, United StatesTaking people
  • UI Health Care Mission Cancer and Blood - Laurel ClinicDes Moines, United StatesTaking people
  • Henry Ford Health Saint John HospitalDetroit, United StatesTaking people
  • Henry Ford HospitalDetroit, United StatesTaking people
  • Essentia Health Saint Mary's - Detroit Lakes ClinicDetroit Lakes, United StatesTaking people
  • Illinois CancerCare-DixonDixon, United StatesNo longer taking part
  • Advocate Good Samaritan HospitalDowners Grove, United StatesTaking people
  • Dublin Methodist HospitalDublin, United StatesTaking people
  • Epic Care-DublinDublin, United StatesNo longer taking part
  • Essentia Health Cancer CenterDuluth, United StatesTaking people
  • Essentia Health Saint Mary's Medical CenterDuluth, United StatesTaking people
  • Miller-Dwan HospitalDuluth, United StatesTaking people
  • CommonSpirit Cancer Center MercyDurango, United StatesNo longer taking part
  • Mercy Medical CenterDurango, United StatesNo longer taking part
  • Prisma Health Cancer Institute - EasleyEasley, United StatesNo longer taking part
  • Henry Ford River District HospitalEast China Township, United StatesNo longer taking part
  • Pocono Medical CenterEast Stroudsburg, United StatesTaking people
  • Hematology Oncology Associates of Central New York-East SyracuseEast Syracuse, United StatesTaking people
  • Marshfield Medical Center-EC Cancer CenterEau Claire, United StatesTaking people
  • Mayo Clinic Health System-Eau Claire ClinicEau Claire, United StatesNo longer taking part
  • Fairview Southdale HospitalEdina, United StatesTaking people
  • Minnesota Oncology - EdinaEdina, United StatesTaking people
  • Swedish Cancer Institute-EdmondsEdmonds, United StatesTaking people
  • Carle Physician Group-EffinghamEffingham, United StatesTaking people
  • Crossroads Cancer CenterEffingham, United StatesTaking people
  • Advocate Sherman HospitalElgin, United StatesTaking people
  • Mercy Cancer Center - Elk GroveElk Grove, United StatesTaking people
  • Bay Area Breast Surgeons IncEmeryville, United StatesNo longer taking part
  • Epic Care Partners in Cancer CareEmeryville, United StatesNo longer taking part
  • Walter Knox Memorial HospitalEmmett, United StatesNo longer taking part
  • The Melanoma and Skin Cancer InstituteEnglewood, United StatesTaking people
  • Mountain Blue Cancer Care Center - SwedishEnglewood, United StatesNo longer taking part
  • Swedish Medical CenterEnglewood, United StatesNo longer taking part
  • Saint Elizabeth HospitalEnumclaw, United StatesNo longer taking part
  • Illinois CancerCare-EurekaEureka, United StatesTaking people
  • NorthShore University HealthSystem-Evanston HospitalEvanston, United StatesTaking people
  • Providence Regional Cancer PartnershipEverett, United StatesTaking people
  • Fairbanks Memorial HospitalFairbanks, United StatesNo longer taking part
  • Smilow Cancer Hospital Care Center-FairfieldFairfield, United StatesTaking people
  • Essentia Health Cancer Center-South University ClinicFargo, United StatesTaking people
  • Parkland Health Center - FarmingtonFarmington, United StatesTaking people
  • Saint Francis HospitalFederal Way, United StatesNo longer taking part
  • Lake Region Healthcare Corporation-Cancer CareFergus Falls, United StatesNo longer taking part
  • Armes Family Cancer CenterFindlay, United StatesTaking people
  • Blanchard Valley HospitalFindlay, United StatesTaking people
  • Orion Cancer CareFindlay, United StatesNo longer taking part
  • Genesys Hurley Cancer InstituteFlint, United StatesTaking people
  • Hurley Medical CenterFlint, United StatesTaking people
  • Cancer Hematology Centers - FlintFlint, United StatesNo longer taking part
  • Genesee Hematology Oncology PCFlint, United StatesNo longer taking part
  • Aurora Health Center-Fond du LacFond du Lac, United StatesTaking people
  • McFarland Clinic - Trinity Cancer CenterFort Dodge, United StatesNo longer taking part
  • UI Healthcare Mission Cancer and Blood - Fort DodgeFort Dodge, United StatesNo longer taking part
  • Holy Cross HospitalFort Lauderdale, United StatesTaking people
  • Mercy Hospital Fort SmithFort Smith, United StatesTaking people
  • UT Southwestern/Simmons Cancer Center-Fort WorthFort Worth, United StatesTaking people
  • Essentia Health - FosstonFosston, United StatesTaking people
  • Atrium Medical Center-Middletown Regional HospitalFranklin, United StatesTaking people
  • Dayton Physicians LLC-AtriumFranklin, United StatesTaking people
  • Unity HospitalFridley, United StatesNo longer taking part
  • Saint Luke's Cancer Institute - FruitlandFruitland, United StatesTaking people
  • Central Ohio Breast and Endocrine SurgeryGahanna, United StatesNo longer taking part
  • Illinois CancerCare-GalesburgGalesburg, United StatesTaking people
  • Western Illinois Cancer Treatment CenterGalesburg, United StatesNo longer taking part
  • Central Care Cancer Center - Garden CityGarden City, United StatesTaking people
  • Northwestern Medicine Cancer Center DelnorGeneva, United StatesNo longer taking part
  • Aurora Health Care Germantown Health CenterGermantown, United StatesTaking people
  • MultiCare Gig Harbor Medical ParkGig Harbor, United StatesNo longer taking part
  • Smilow Cancer Hospital Care Center at GlastonburyGlastonbury, United StatesTaking people
  • Glens Falls HospitalGlens Falls, United StatesNo longer taking part
  • NorthShore University HealthSystem-Glenbrook HospitalGlenview, United StatesTaking people
  • National Jewish Health-Western Hematology OncologyGolden, United StatesNo longer taking part
  • CTCA at Western Regional Medical CenterGoodyear, United StatesTaking people
  • Aurora Cancer Care-GraftonGrafton, United StatesTaking people
  • Nebraska Cancer Specialists/Oncology Hematology West PCGrand Island, United StatesNo longer taking part
  • Saint Mary's Hospital and Regional Medical CenterGrand Junction, United StatesNo longer taking part
  • Corewell Health Grand Rapids Hospitals - Butterworth HospitalGrand Rapids, United StatesTaking people
  • Corewell Health Grand Rapids Hospitals - Helen DeVos Children's HospitalGrand Rapids, United StatesTaking people
  • Trinity Health Grand Rapids HospitalGrand Rapids, United StatesNo longer taking part
  • Central Care Cancer Center - Great BendGreat Bend, United StatesNo longer taking part
  • Benefis Sletten Cancer InstituteGreat Falls, United StatesTaking people
  • Great Falls ClinicGreat Falls, United StatesTaking people
  • Banner North Colorado Medical CenterGreeley, United StatesNo longer taking part
  • Aurora BayCare Medical CenterGreen Bay, United StatesTaking people
  • Saint Vincent Hospital Cancer Center at Saint Mary'sGreen Bay, United StatesTaking people
  • Saint Vincent Hospital Cancer Center Green BayGreen Bay, United StatesTaking people
  • East Carolina UniversityGreenville, United StatesTaking people
  • Miami Valley Cancer Care and InfusionGreenville, United StatesTaking people
  • Prisma Health Cancer Institute - EastsideGreenville, United StatesTaking people
  • Prisma Health Cancer Institute - FarisGreenville, United StatesTaking people
  • Prisma Health Greenville Memorial HospitalGreenville, United StatesTaking people
  • Wayne HospitalGreenville, United StatesTaking people
  • Dayton Physicians LLC-WayneGreenville, United StatesNo longer taking part
  • Prisma Health Cancer Institute - ButternutGreenville, United StatesNo longer taking part
  • Smilow Cancer Hospital Care Center at GreenwichGreenwich, United StatesTaking people
  • Self Regional HealthcareGreenwood, United StatesNo longer taking part
  • Prisma Health Cancer Institute - GreerGreer, United StatesTaking people
  • Henry Ford Saint John Hospital - Van ElslanderGrosse Pointe Woods, United StatesTaking people
  • Henry Ford Saint John Hospital - AcademicGrosse Pointe Woods, United StatesNo longer taking part
  • Henry Ford Saint John Hospital - BreastGrosse Pointe Woods, United StatesNo longer taking part
  • Mount Carmel Grove City HospitalGrove City, United StatesTaking people
  • Smilow Cancer Hospital Care Center - GuilfordGuilford, United StatesTaking people
  • Smilow Cancer Hospital Care Center at Saint FrancisHartford, United StatesTaking people
  • Ingalls Memorial HospitalHarvey, United StatesNo longer taking part
  • Hi-Line Sletten Cancer CenterHavre, United StatesTaking people
  • Essentia Health-Hayward ClinicHayward, United StatesTaking people
  • Advocate South Suburban HospitalHazel Crest, United StatesTaking people
  • Geisinger Medical Center-Cancer Center HazletonHazleton, United StatesTaking people
  • Lehigh Valley Hospital-HazletonHazleton, United StatesNo longer taking part
  • Comprehensive Cancer Centers of Nevada - HendersonHenderson, United StatesTaking people
  • Cancer and Blood Specialists-HendersonHenderson, United StatesNo longer taking part
  • Comprehensive Cancer Centers of Nevada-Horizon RidgeHenderson, United StatesNo longer taking part
  • Comprehensive Cancer Centers of Nevada-Southeast HendersonHenderson, United StatesNo longer taking part
  • Las Vegas Cancer Center-HendersonHenderson, United StatesNo longer taking part
  • Las Vegas Urology - Green ValleyHenderson, United StatesNo longer taking part
  • Las Vegas Urology - PebbleHenderson, United StatesNo longer taking part
  • Oncology Las Vegas - HendersonHenderson, United StatesNo longer taking part
  • Urology Specialists of Nevada - Green ValleyHenderson, United StatesNo longer taking part
  • Penn State Milton S. Hershey Medical CenterHershey, United StatesTaking people
  • Essentia Health Hibbing ClinicHibbing, United StatesTaking people
  • NorthShore University HealthSystem-Highland Park HospitalHighland Park, United StatesTaking people
  • University of North Carolina-Hillsborough CampusHillsborough, United StatesTaking people
  • Loyola Medicine Homer GlenHomer Glen, United StatesNo longer taking part
  • CHI Saint Vincent Cancer Center Hot SpringsHot Springs, United StatesNo longer taking part
  • Houston Methodist HospitalHouston, United StatesTaking people
  • Houston Methodist West HospitalHouston, United StatesTaking people
  • Methodist Willowbrook HospitalHouston, United StatesTaking people
  • UT MD Anderson - West HoustonHouston, United StatesTaking people
  • UT MD Anderson Cancer CenterHouston, United StatesTaking people
  • Indiana University/Melvin and Bren Simon Cancer CenterIndianapolis, United StatesNo longer taking part
  • IU Health Methodist HospitalIndianapolis, United StatesNo longer taking part
  • Sidney and Lois Eskenazi HospitalIndianapolis, United StatesNo longer taking part
  • Springmill Medical CenterIndianapolis, United StatesNo longer taking part
  • University of Iowa/Holden Comprehensive Cancer CenterIowa City, United StatesTaking people
  • Swedish Cancer Institute-IssaquahIssaquah, United StatesTaking people
  • Allegiance HealthJackson, United StatesTaking people
  • Essentia Health - Jamestown ClinicJamestown, United StatesTaking people
  • Mercyhealth Hospital and Cancer Center - JanesvilleJanesville, United StatesTaking people
  • McFarland Clinic - JeffersonJefferson, United StatesNo longer taking part
  • MU Health Care Goldschmidt Cancer CenterJefferson City, United StatesNo longer taking part
  • Emory Johns Creek HospitalJohns Creek, United StatesTaking people
  • University of Wisconsin Carbone Cancer Center - Johnson CreekJohnson Creek, United StatesTaking people
  • Duly Health and Care JolietJoliet, United StatesNo longer taking part
  • Freeman Health SystemJoplin, United StatesTaking people
  • Mercy Hospital JoplinJoplin, United StatesTaking people
  • Beacon KalamazooKalamazoo, United StatesTaking people
  • Bronson Methodist HospitalKalamazoo, United StatesTaking people
  • West Michigan Cancer CenterKalamazoo, United StatesTaking people
  • Logan Health Medical CenterKalispell, United StatesTaking people
  • Saint Luke's Hospital of Kansas CityKansas City, United StatesNo longer taking part
  • CHI Health Good SamaritanKearney, United StatesTaking people
  • ECU Health Oncology KenansvilleKenansville, United StatesTaking people
  • Kadlec Clinic Hematology and OncologyKennewick, United StatesTaking people
  • Aurora Cancer Care-Kenosha SouthKenosha, United StatesTaking people
  • Greater Dayton Cancer CenterKettering, United StatesTaking people
  • Kettering Medical CenterKettering, United StatesTaking people
  • First Dayton Cancer CareKettering, United StatesNo longer taking part
  • Illinois CancerCare-Kewanee ClinicKewanee, United StatesTaking people
  • Kingman Regional Medical CenterKingman, United StatesTaking people
  • ECU Health Oncology KinstonKinston, United StatesTaking people
  • FHCC at EvergreenHealthKirkland, United StatesTaking people
  • Gundersen Lutheran Medical CenterLa Crosse, United StatesTaking people
  • UC San Diego Moores Cancer CenterLa Jolla, United StatesNo longer taking part
  • Providence Regional Cancer System-LaceyLacey, United StatesTaking people
  • Good Samaritan Hospital - Cancer Centers of ColoradoLafayette, United StatesNo longer taking part
  • CommonSpirit Saint Anthony Hospital Cancer CenterLakewood, United StatesTaking people
  • Saint Clare HospitalLakewood, United StatesNo longer taking part
  • Fairfield Medical CenterLancaster, United StatesNo longer taking part
  • University of Michigan Health - Sparrow LansingLansing, United StatesTaking people
  • Alliance for Childhood Diseases/Cure 4 the Kids FoundationLas Vegas, United StatesTaking people
  • Comprehensive Cancer Centers of NevadaLas Vegas, United StatesTaking people
  • Comprehensive Cancer Centers of Nevada - Central ValleyLas Vegas, United StatesTaking people
  • Comprehensive Cancer Centers of Nevada - NorthwestLas Vegas, United StatesTaking people
  • Comprehensive Cancer Centers of Nevada - Town CenterLas Vegas, United StatesTaking people
  • Comprehensive Cancer Centers of Nevada-SummerlinLas Vegas, United StatesTaking people
  • OptumCare Cancer Care at CharlestonLas Vegas, United StatesTaking people
  • OptumCare Cancer Care at Fort ApacheLas Vegas, United StatesTaking people
  • OptumCare Cancer Care at MountainViewLas Vegas, United StatesTaking people
  • Radiation Oncology Centers of Nevada CentralLas Vegas, United StatesTaking people
  • Radiation Oncology Centers of Nevada SoutheastLas Vegas, United StatesTaking people
  • Summerlin Hospital Medical CenterLas Vegas, United StatesTaking people
  • Ann M Wierman MD LTDLas Vegas, United StatesNo longer taking part
  • Cancer and Blood Specialists-ShadowLas Vegas, United StatesNo longer taking part
  • Cancer and Blood Specialists-TenayaLas Vegas, United StatesNo longer taking part
  • Desert West SurgeryLas Vegas, United StatesNo longer taking part
  • HealthCare Partners Medical Group Oncology/Hematology-Centennial HillsLas Vegas, United StatesNo longer taking part
  • HealthCare Partners Medical Group Oncology/Hematology-Maryland ParkwayLas Vegas, United StatesNo longer taking part
  • HealthCare Partners Medical Group Oncology/Hematology-San MartinLas Vegas, United StatesNo longer taking part
  • HealthCare Partners Medical Group Oncology/Hematology-TenayaLas Vegas, United StatesNo longer taking part
  • Hope Cancer Care of NevadaLas Vegas, United StatesNo longer taking part
  • Las Vegas Cancer Center-Medical CenterLas Vegas, United StatesNo longer taking part
  • Las Vegas Prostate Cancer CenterLas Vegas, United StatesNo longer taking part
  • Las Vegas Urology - Cathedral RockLas Vegas, United StatesNo longer taking part
  • Las Vegas Urology - PecosLas Vegas, United StatesNo longer taking part
  • Las Vegas Urology - Smoke RanchLas Vegas, United StatesNo longer taking part
  • Las Vegas Urology - SunsetLas Vegas, United StatesNo longer taking part
  • Oncology Las Vegas - TenayaLas Vegas, United StatesNo longer taking part
  • Sunrise Hospital and Medical CenterLas Vegas, United StatesNo longer taking part
  • University Cancer CenterLas Vegas, United StatesNo longer taking part
  • University Medical Center of Southern NevadaLas Vegas, United StatesNo longer taking part
  • Urology Specialists of Nevada - CentralLas Vegas, United StatesNo longer taking part
  • Urology Specialists of Nevada - NorthwestLas Vegas, United StatesNo longer taking part
  • Urology Specialists of Nevada - SouthwestLas Vegas, United StatesNo longer taking part
  • UT MD Anderson - League CityLeague City, United StatesTaking people
  • Saint Luke's East - Lee's SummitLee's Summit, United StatesNo longer taking part
  • Geisinger Medical Oncology-LewisburgLewisburg, United StatesTaking people
  • Lewistown HospitalLewistown, United StatesTaking people
  • CommonSpirit Saint Joseph Hospital - LexingtonLexington, United StatesTaking people
  • CommonSpirit Saint Joseph Medical Center - East LexingtonLexington, United StatesTaking people
  • Saint Joseph Radiation Oncology Resource CenterLexington, United StatesTaking people
  • University of Kentucky/Markey Cancer CenterLexington, United StatesNo longer taking part
  • AMG Libertyville - OncologyLibertyville, United StatesTaking people
  • Condell Memorial HospitalLibertyville, United StatesTaking people
  • Saint Rita's Medical CenterLima, United StatesTaking people
  • Saint Elizabeth Regional Medical CenterLincoln, United StatesNo longer taking part
  • Rocky Mountain Cancer Centers-LittletonLittleton, United StatesTaking people
  • AdventHealth LittletonLittleton, United StatesNo longer taking part
  • Trinity Health Saint Mary Mercy Livonia HospitalLivonia, United StatesTaking people
  • Hope Cancer ClinicLivonia, United StatesNo longer taking part
  • Logan Regional HospitalLogan, United StatesNo longer taking part
  • CommonSpirit Saint Joseph Hospital LondonLondon, United StatesNo longer taking part
  • Rocky Mountain Cancer Centers-Sky RidgeLone Tree, United StatesNo longer taking part
  • Sky Ridge Medical CenterLone Tree, United StatesNo longer taking part
  • Longmont United HospitalLongmont, United StatesTaking people
  • Rocky Mountain Cancer Centers-LongmontLongmont, United StatesNo longer taking part
  • PeaceHealth Saint John Medical CenterLongview, United StatesTaking people
  • The James Graham Brown Cancer Center at University of LouisvilleLouisville, United StatesTaking people
  • UofL Health Medical Center NortheastLouisville, United StatesTaking people
  • Jewish HospitalLouisville, United StatesNo longer taking part
  • Saints Mary and Elizabeth HospitalLouisville, United StatesNo longer taking part
  • Banner North Colorado Medical Center - Loveland CampusLoveland, United StatesNo longer taking part
  • Henry Ford Saint John Hospital - Macomb MedicalMacomb, United StatesTaking people
  • Illinois CancerCare-MacombMacomb, United StatesTaking people
  • Henry Ford Warren Hospital - Breast MacombMacomb, United StatesNo longer taking part
  • University of Wisconsin Carbone Cancer Center - Eastpark Medical CenterMadison, United StatesTaking people
  • University of Wisconsin Carbone Cancer Center - University HospitalMadison, United StatesTaking people
  • OhioHealth Mansfield HospitalMansfield, United StatesTaking people
  • Fairview Clinics and Surgery Center Maple GroveMaple Grove, United StatesTaking people
  • Minnesota Oncology - Maple GroveMaple Grove, United StatesTaking people
  • Minnesota Oncology Hematology PA-MaplewoodMaplewood, United StatesTaking people
  • Saint John's Hospital - HealtheastMaplewood, United StatesTaking people
  • Marietta Memorial HospitalMarietta, United StatesTaking people
  • Aurora Bay Area Medical Group-MarinetteMarinette, United StatesTaking people
  • OhioHealth Marion General HospitalMarion, United StatesTaking people
  • Saint Mary's Oncology/Hematology Associates of MarletteMarlette, United StatesNo longer taking part
  • McFarland Clinic - MarshalltownMarshalltown, United StatesNo longer taking part
  • Marshfield Medical Center-MarshfieldMarshfield, United StatesTaking people
  • Contra Costa Regional Medical CenterMartinez, United StatesTaking people
  • WVUH-Berkely Medical CenterMartinsburg, United StatesNo longer taking part
  • Carle Physician Group-Mattoon/CharlestonMattoon, United StatesTaking people
  • UH Seidman Cancer Center at Landerbrook Health CenterMayfield Heights, United StatesNo longer taking part
  • Loyola University Medical CenterMaywood, United StatesTaking people
  • Marjorie Weinberg Cancer Center at Loyola-GottliebMelrose Park, United StatesNo longer taking part
  • UH Seidman Cancer Center at Lake Health Mentor CampusMentor, United StatesTaking people
  • Mercy Cancer CenterMerced, United StatesNo longer taking part
  • Idaho Urologic Institute-MeridianMeridian, United StatesTaking people
  • Saint Luke's Cancer Institute - MeridianMeridian, United StatesTaking people
  • UH Seidman Cancer Center at Southwest General HospitalMiddleburg Heights, United StatesTaking people
  • MyMichigan Medical Center MidlandMidland, United StatesTaking people
  • Aurora Cancer Care-MilwaukeeMilwaukee, United StatesTaking people
  • Aurora Saint Luke's Medical CenterMilwaukee, United StatesTaking people
  • Aurora Sinai Medical CenterMilwaukee, United StatesTaking people
  • Abbott-Northwestern HospitalMinneapolis, United StatesTaking people
  • Health Partners IncMinneapolis, United StatesTaking people
  • Hennepin County Medical CenterMinneapolis, United StatesTaking people
  • Marshfield Medical Center - MinocquaMinocqua, United StatesTaking people
  • Community Medical CenterMissoula, United StatesTaking people
  • Saint Patrick Hospital - Community HospitalMissoula, United StatesTaking people
  • Ochsner LSU Health Monroe Medical CenterMonroe, United StatesNo longer taking part
  • Toledo Clinic Cancer Centers-MonroeMonroe, United StatesNo longer taking part
  • Monticello Cancer CenterMonticello, United StatesTaking people
  • West Virginia University HealthcareMorgantown, United StatesTaking people
  • Morristown Medical CenterMorristown, United StatesTaking people
  • Skagit Regional Health Cancer Care CenterMount Vernon, United StatesTaking people
  • SSM Health Good SamaritanMount Vernon, United StatesTaking people
  • Knox Community HospitalMount Vernon, United StatesNo longer taking part
  • ProHealth D N Greenwald CenterMukwonago, United StatesTaking people
  • Intermountain Medical CenterMurray, United StatesNo longer taking part
  • Trinity Health Muskegon HospitalMuskegon, United StatesNo longer taking part
  • Saint Alphonsus Cancer Care Center-NampaNampa, United StatesTaking people
  • Saint Luke's Cancer Institute - NampaNampa, United StatesTaking people
  • Vanderbilt University/Ingram Cancer CenterNashville, United StatesTaking people
  • Houston Methodist Saint John HospitalNassau Bay, United StatesTaking people
  • Mount Carmel New Albany Surgical HospitalNew Albany, United StatesTaking people
  • Smilow Cancer Center/Yale-New Haven HospitalNew Haven, United StatesTaking people
  • Yale UniversityNew Haven, United StatesTaking people
  • Ochsner Medical Center JeffersonNew Orleans, United StatesTaking people
  • Tulane University School of MedicineNew Orleans, United StatesTaking people
  • Cancer Center of Western WisconsinNew Richmond, United StatesTaking people
  • New Ulm Medical CenterNew Ulm, United StatesNo longer taking part
  • Mount Sinai ChelseaNew York, United StatesTaking people
  • Mount Sinai HospitalNew York, United StatesTaking people
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer CenterNew York, United StatesTaking people
  • Licking Memorial HospitalNewark, United StatesTaking people
  • Newark Radiation OncologyNewark, United StatesTaking people
  • Providence Newberg Medical CenterNewberg, United StatesTaking people
  • Corewell Health Lakeland Hospitals - Niles HospitalNiles, United StatesTaking people
  • Illinois Cancer Specialists-NilesNiles, United StatesNo longer taking part
  • Carle BroMenn Medical CenterNormal, United StatesTaking people
  • Carle Cancer Institute NormalNormal, United StatesTaking people
  • Yale-New Haven Hospital North Haven Medical CenterNorth Haven, United StatesTaking people
  • Cancer and Hematology Centers of Western Michigan - Norton ShoresNorton Shores, United StatesNo longer taking part
  • Henry Ford Health Providence Novi HospitalNovi, United StatesTaking people
  • Henry Ford Medical Center-ColumbusNovi, United StatesTaking people
  • Cancer Care Center of O'FallonO'Fallon, United StatesTaking people
  • HSHS Saint Elizabeth's HospitalO'Fallon, United StatesTaking people
  • Advocate Christ Medical CenterOak Lawn, United StatesTaking people
  • Alta Bates Summit Medical Center - Summit CampusOakland, United StatesNo longer taking part
  • Bay Area Tumor InstituteOakland, United StatesNo longer taking part
  • ProHealth Oconomowoc Memorial HospitalOconomowoc, United StatesTaking people
  • Saint Vincent Hospital Cancer Center at Oconto FallsOconto Falls, United StatesTaking people
  • McKay-Dee Hospital CenterOgden, United StatesNo longer taking part
  • Mercy Hospital Oklahoma CityOklahoma City, United StatesTaking people
  • Alegent Health Bergan Mercy Medical CenterOmaha, United StatesTaking people
  • University of Nebraska Medical CenterOmaha, United StatesTaking people
  • Alegent Health Immanuel Medical CenterOmaha, United StatesNo longer taking part
  • Alegent Health Lakeside HospitalOmaha, United StatesNo longer taking part
  • Nebraska Medicine-Village PointeOmaha, United StatesNo longer taking part
  • Saint Alphonsus Cancer Care Center-OntarioOntario, United StatesNo longer taking part
  • Smilow Cancer Hospital-Orange Care CenterOrange, United StatesTaking people
  • Providence Willamette Falls Medical CenterOregon City, United StatesTaking people
  • Lake Regional HospitalOsage Beach, United StatesTaking people
  • Vince Lombardi Cancer Clinic - OshkoshOshkosh, United StatesTaking people
  • Upstate Cancer Center at OswegoOswego, United StatesNo longer taking part
  • Illinois CancerCare-Ottawa ClinicOttawa, United StatesTaking people
  • Saint Luke's South HospitalOverland Park, United StatesNo longer taking part
  • Hope Cancer Care of Nevada-PahrumpPahrump, United StatesNo longer taking part
  • Midlands Community HospitalPapillion, United StatesNo longer taking part
  • Essentia Health - Park RapidsPark Rapids, United StatesTaking people
  • Advocate Lutheran General HospitalPark Ridge, United StatesTaking people
  • AdventHealth ParkerParker, United StatesNo longer taking part
  • Camden Clark Medical CenterParkersburg, United StatesTaking people
  • Illinois CancerCare-PekinPekin, United StatesTaking people
  • Illinois CancerCare-PeoriaPeoria, United StatesTaking people
  • Methodist Medical Center of IllinoisPeoria, United StatesTaking people
  • Mercy Health - Perrysburg HospitalPerrysburg, United StatesTaking people
  • Illinois CancerCare-PeruPeru, United StatesTaking people
  • Valley Radiation OncologyPeru, United StatesNo longer taking part
  • Thomas Jefferson University HospitalPhiladelphia, United StatesNo longer taking part
  • Cancer Center at Saint Joseph'sPhoenix, United StatesTaking people
  • Mayo Clinic Hospital in ArizonaPhoenix, United StatesNo longer taking part
  • Mercy Hospital PittsburgPittsburg, United StatesTaking people
  • Allegheny General HospitalPittsburgh, United StatesTaking people
  • West Penn HospitalPittsburgh, United StatesTaking people
  • Michigan Healthcare Professionals PontiacPontiac, United StatesTaking people
  • Trinity Health Saint Joseph Mercy Oakland HospitalPontiac, United StatesTaking people
  • Hope Cancer CenterPontiac, United StatesNo longer taking part
  • Newland Medical Associates-PontiacPontiac, United StatesNo longer taking part
  • Huron Medical Center PCPort Huron, United StatesNo longer taking part
  • Lake Huron Medical CenterPort Huron, United StatesNo longer taking part
  • Jefferson HealthcarePort Townsend, United StatesNo longer taking part
  • Providence Portland Medical CenterPortland, United StatesTaking people
  • Providence Saint Vincent Medical CenterPortland, United StatesTaking people
  • Oregon Health and Science UniversityPortland, United StatesNo longer taking part
  • Southern Ohio Medical CenterPortsmouth, United StatesTaking people
  • Kootenai Clinic Cancer Services - Post FallsPost Falls, United StatesTaking people
  • Pottstown HospitalPottstown, United StatesNo longer taking part
  • Geisinger Cancer Services-PottsvillePottsville, United StatesTaking people
  • Harrison HealthPartners Hematology and Oncology-PoulsboPoulsbo, United StatesNo longer taking part
  • Illinois CancerCare-PrincetonPrinceton, United StatesTaking people
  • Fairview Northland Medical CenterPrinceton, United StatesNo longer taking part
  • Utah Valley Regional Medical CenterProvo, United StatesNo longer taking part
  • Saint Mary Corwin Medical CenterPueblo, United StatesTaking people
  • MultiCare Good Samaritan HospitalPuyallup, United StatesNo longer taking part
  • Aurora Cancer Care-RacineRacine, United StatesTaking people
  • Eisenhower Medical CenterRancho Mirage, United StatesNo longer taking part
  • Rapid City Regional HospitalRapid City, United StatesTaking people
  • Saint Charles Health System-RedmondRedmond, United StatesNo longer taking part
  • Corewell Health Reed City HospitalReed City, United StatesTaking people
  • Renown Regional Medical CenterReno, United StatesTaking people
  • Radiation Oncology AssociatesReno, United StatesNo longer taking part
  • Saint Mary's Regional Medical CenterReno, United StatesNo longer taking part
  • Valley Medical CenterRenton, United StatesTaking people
  • Marshfield Medical Center-Rice LakeRice Lake, United StatesTaking people
  • UT Southwestern Clinical Center at Richardson/PlanoRichardson, United StatesTaking people
  • ECU Health Oncology RichlandsRichlands, United StatesTaking people
  • Reid HealthRichmond, United StatesTaking people
  • Riverton HospitalRiverton, United StatesNo longer taking part
  • North Memorial Medical Health CenterRobbinsdale, United StatesTaking people
  • Mayo Clinic in RochesterRochester, United StatesNo longer taking part
  • Henry Ford Rochester HospitalRochester Hills, United StatesNo longer taking part
  • Mercy Cancer Center - RocklinRocklin, United StatesTaking people
  • Mercy Clinic-Rolla-Cancer and HematologyRolla, United StatesTaking people
  • Phelps Health Delbert Day Cancer InstituteRolla, United StatesTaking people
  • Mercy Cancer Center - SacramentoSacramento, United StatesTaking people
  • MyMichigan Medical Center SaginawSaginaw, United StatesTaking people
  • Oncology Hematology Associates of Saginaw Valley PCSaginaw, United StatesNo longer taking part
  • Corewell Health Lakeland Hospitals - Marie Yeager Cancer CenterSaint Joseph, United StatesTaking people
  • Corewell Health Lakeland Hospitals - Saint Joseph HospitalSaint Joseph, United StatesTaking people
  • Heartland Regional Medical CenterSaint Joseph, United StatesTaking people
  • Park Nicollet Clinic - Saint Louis ParkSaint Louis Park, United StatesTaking people
  • Regions HospitalSaint Paul, United StatesTaking people
  • United HospitalSaint Paul, United StatesTaking people
  • Sainte Genevieve County Memorial HospitalSainte Genevieve, United StatesTaking people
  • Salinas Valley MemorialSalinas, United StatesNo longer taking part
  • Huntsman Cancer Institute/University of UtahSalt Lake City, United StatesTaking people
  • LDS HospitalSalt Lake City, United StatesNo longer taking part
  • Utah Cancer Specialists-Salt Lake CitySalt Lake City, United StatesNo longer taking part
  • Pacific Central Coast Health Center-San Luis ObispoSan Luis Obispo, United StatesTaking people
  • Kootenai Clinic Cancer Services - SandpointSandpoint, United StatesNo longer taking part
  • Essentia Health SandstoneSandstone, United StatesTaking people
  • UH Seidman Cancer Center at Firelands Regional Medical CenterSandusky, United StatesTaking people
  • Mission Hope Medical Oncology - Santa MariaSanta Maria, United StatesTaking people
  • Lewis Cancer and Research Pavilion at Saint Joseph's/CandlerSavannah, United StatesNo longer taking part
  • Mayo Clinic in ArizonaScottsdale, United StatesNo longer taking part
  • Community Medical CenterScranton, United StatesNo longer taking part
  • FHCC at Northwest HospitalSeattle, United StatesTaking people
  • Fred Hutchinson Cancer CenterSeattle, United StatesTaking people
  • Swedish Medical Center-Ballard CampusSeattle, United StatesTaking people
  • Swedish Medical Center-Cherry HillSeattle, United StatesTaking people
  • Swedish Medical Center-First HillSeattle, United StatesTaking people
  • University of Washington Medical Center - MontlakeSeattle, United StatesTaking people
  • Pacific Gynecology SpecialistsSeattle, United StatesNo longer taking part
  • PeaceHealth United General Medical CenterSedro-Woolley, United StatesTaking people
  • Geisinger Medical Oncology-SelinsgroveSelinsgrove, United StatesTaking people
  • Prisma Health Cancer Institute - SenecaSeneca, United StatesTaking people
  • Saint Francis Regional Medical CenterShakopee, United StatesTaking people
  • ThedaCare Cancer Care - ShawanoShawano, United StatesTaking people
  • Vince Lombardi Cancer Clinic-SheboyganSheboygan, United StatesTaking people
  • Henry Ford Macomb Health Center - Shelby TownshipShelby, United StatesNo longer taking part
  • Providence Regional Cancer System-SheltonShelton, United StatesNo longer taking part
  • Jewish Hospital Medical Center SouthShepherdsville, United StatesNo longer taking part
  • Welch Cancer CenterSheridan, United StatesNo longer taking part
  • LSU Health Sciences Center at ShreveportShreveport, United StatesTaking people
  • Saint Joseph Medical Center Hematology and Oncology - SilverdaleSilverdale, United StatesTaking people
  • Avera Cancer InstituteSioux Falls, United StatesNo longer taking part
  • North Shore Medical CenterSkokie, United StatesNo longer taking part
  • Henry Ford Health Providence Southfield HospitalSouthfield, United StatesTaking people
  • Cancer Care Northwest - Spokane SouthSpokane, United StatesTaking people
  • Cancer Care Northwest-North SpokaneSpokane, United StatesTaking people
  • MultiCare Deaconess Cancer and Blood Specialty Center - DowntownSpokane, United StatesNo longer taking part
  • MultiCare Deaconess Cancer and Blood Specialty Center - NorthSpokane, United StatesNo longer taking part
  • MultiCare Deaconess Cancer and Blood Specialty Center - ValleySpokane Valley, United StatesNo longer taking part
  • Essentia Health-Spooner ClinicSpooner, United StatesTaking people
  • CoxHealth South HospitalSpringfield, United StatesTaking people
  • Mercy Hospital SpringfieldSpringfield, United StatesTaking people
  • Southern Illinois University School of MedicineSpringfield, United StatesTaking people
  • Springfield ClinicSpringfield, United StatesTaking people
  • Springfield Memorial HospitalSpringfield, United StatesTaking people
  • Springfield Regional Cancer CenterSpringfield, United StatesTaking people
  • Springfield Regional Medical CenterSpringfield, United StatesTaking people
  • Mercy Medical CenterSpringfield, United StatesNo longer taking part
  • Mercy Hospital Saint LouisSt Louis, United StatesTaking people
  • Mercy Hospital SouthSt Louis, United StatesTaking people
  • Missouri Baptist Medical CenterSt Louis, United StatesTaking people
  • Siteman Cancer Center at Christian HospitalSt Louis, United StatesTaking people
  • Siteman Cancer Center-South CountySt Louis, United StatesTaking people
  • Washington University School of MedicineSt Louis, United StatesTaking people
  • Mercy Infusion Center - ChippewaSt Louis, United StatesNo longer taking part
  • Saint George Regional Medical CenterSt. George, United StatesNo longer taking part
  • Smilow Cancer Hospital Care Center at Long RidgeStamford, United StatesTaking people
  • Geisinger Medical GroupState College, United StatesNo longer taking part
  • Bhadresh Nayak MD PC-Sterling HeightsSterling Heights, United StatesNo longer taking part
  • Marshfield Medical Center-River Region at Stevens PointStevens Point, United StatesTaking people
  • Lakeview HospitalStillwater, United StatesTaking people
  • Saint Joseph's Medical CenterStockton, United StatesTaking people
  • Saint Vincent Hospital Cancer Center at Sturgeon BaySturgeon Bay, United StatesTaking people
  • Houston Methodist Sugar Land HospitalSugar Land, United StatesTaking people
  • UT MD Anderson - Sugar LandSugar Land, United StatesTaking people
  • Missouri Baptist Sullivan HospitalSullivan, United StatesTaking people
  • Aurora Medical Center in SummitSummit, United StatesTaking people
  • Overlook HospitalSummit, United StatesTaking people
  • Essentia Health Saint Mary's Hospital - SuperiorSuperior, United StatesTaking people
  • State University of New York Upstate Medical UniversitySyracuse, United StatesNo longer taking part
  • SUNY Upstate Medical Center-Community CampusSyracuse, United StatesNo longer taking part
  • Franciscan Research Center-Northwest Medical PlazaTacoma, United StatesNo longer taking part
  • Mary Bridge Children's Hospital and Health CenterTacoma, United StatesNo longer taking part
  • MultiCare Tacoma General HospitalTacoma, United StatesNo longer taking part
  • MyMichigan Medical Center TawasTawas City, United StatesTaking people
  • Houston Methodist The Woodlands HospitalThe Woodlands, United StatesTaking people
  • Lewis Hall Singletary Oncology CenterThomasville, United StatesTaking people
  • Rocky Mountain Cancer Centers-ThorntonThornton, United StatesTaking people
  • National Jewish Health-Northern Hematology OncologyThornton, United StatesNo longer taking part
  • Mercy Health - Saint Anne HospitalToledo, United StatesNo longer taking part
  • Mercy Health - Saint Vincent HospitalToledo, United StatesNo longer taking part
  • Mercy Health Sylvania Radiation Oncology CenterToledo, United StatesNo longer taking part
  • Toledo Clinic Cancer Centers-ToledoToledo, United StatesNo longer taking part
  • Cotton O'Neil Cancer Center / Stormont Vail HealthTopeka, United StatesTaking people
  • Smilow Cancer Hospital-Torrington Care CenterTorrington, United StatesTaking people
  • Munson Medical CenterTraverse City, United StatesTaking people
  • Upper Valley Medical CenterTroy, United StatesTaking people
  • Dayton Physicians LLC - TroyTroy, United StatesNo longer taking part
  • Smilow Cancer Hospital Care Center-TrumbullTrumbull, United StatesTaking people
  • Banner University Medical Center - TucsonTucson, United StatesNo longer taking part
  • University of Arizona Cancer Center-North CampusTucson, United StatesNo longer taking part
  • Oklahoma Cancer Specialists and Research Institute-TulsaTulsa, United StatesTaking people
  • Saint Luke's Cancer Institute - Twin FallsTwin Falls, United StatesTaking people
  • Vince Lombardi Cancer Clinic-Two RiversTwo Rivers, United StatesTaking people
  • Carle Cancer CenterUrbana, United StatesTaking people
  • The Carle Foundation HospitalUrbana, United StatesTaking people
  • South Georgia Medical Center/Pearlman Cancer CenterValdosta, United StatesTaking people
  • PeaceHealth Southwest Medical CenterVancouver, United StatesTaking people
  • Upstate Cancer Center at VeronaVerona, United StatesNo longer taking part
  • Essentia Health Virginia ClinicVirginia, United StatesTaking people
  • MD Anderson Cancer Center at Cooper-VoorheesVoorhees Township, United StatesTaking people
  • Ridgeview Medical CenterWaconia, United StatesTaking people
  • Providence Saint Mary Regional Cancer CenterWalla Walla, United StatesTaking people
  • BASS Medical Group - LennonWalnut Creek, United StatesTaking people
  • Epic Care Cyberknife CenterWalnut Creek, United StatesNo longer taking part
  • Henry Ford Health Warren HospitalWarren, United StatesTaking people
  • Saint Joseph Warren HospitalWarren, United StatesTaking people
  • Advanced Breast Care Center PLLCWarren, United StatesNo longer taking part
  • Henry Ford Madison Heights Hospital - BreastWarren, United StatesNo longer taking part
  • Henry Ford Warren Hospital - GLCMSWarren, United StatesNo longer taking part
  • Macomb Hematology Oncology PCWarren, United StatesNo longer taking part
  • Northwestern Medicine Cancer Center WarrenvilleWarrenville, United StatesNo longer taking part
  • Illinois CancerCare - WashingtonWashington, United StatesTaking people
  • Marion L Shepard Cancer Center - ECU Health Beaufort HospitalWashington, United StatesTaking people
  • Mercy Hospital WashingtonWashington, United StatesNo longer taking part
  • Smilow Cancer Hospital-Waterbury Care CenterWaterbury, United StatesTaking people
  • Smilow Cancer Hospital Care Center - WaterfordWaterford, United StatesTaking people
  • UI Health Care Mission Cancer and Blood - Waukee ClinicWaukee, United StatesTaking people
  • UW Cancer Center at ProHealth CareWaukesha, United StatesTaking people
  • ProHealth Waukesha Memorial HospitalWaukesha, United StatesNo longer taking part
  • Aurora Cancer Care-Milwaukee WestWauwatosa, United StatesTaking people
  • Aurora West Allis Medical CenterWest Allis, United StatesTaking people
  • Henry Ford West Bloomfield HospitalWest Bloomfield, United StatesTaking people
  • Saint Mary's Oncology/Hematology Associates of West BranchWest Branch, United StatesNo longer taking part
  • Mercy Medical Center-West LakesWest Des Moines, United StatesTaking people
  • Methodist West HospitalWest Des Moines, United StatesTaking people
  • Reading HospitalWest Reading, United StatesTaking people
  • Smilow Cancer Hospital Care Center - WesterlyWesterly, United StatesTaking people
  • OhioHealth Westerville Medical Campus/Westerville Cancer CenterWesterville, United StatesTaking people
  • Saint Ann's HospitalWesterville, United StatesTaking people
  • UH Seidman Cancer Center at Saint John Medical CenterWestlake, United StatesTaking people
  • Saint Anthony North HospitalWestminster, United StatesTaking people
  • Cleveland Clinic-WestonWeston, United StatesTaking people
  • Marshfield Medical Center - WestonWeston, United StatesTaking people
  • Intermountain Health Lutheran HospitalWheat Ridge, United StatesNo longer taking part
  • Wheeling Hospital/Schiffler Cancer CenterWheeling, United StatesTaking people
  • Geisinger Wyoming Valley/Henry Cancer CenterWilkes-Barre, United StatesTaking people
  • Rice Memorial HospitalWillmar, United StatesTaking people
  • Minnesota Oncology Hematology PA-WoodburyWoodbury, United StatesTaking people
  • Woodland Memorial HospitalWoodland, United StatesTaking people
  • Cleveland Clinic Wooster Family Health and Surgery CenterWooster, United StatesTaking people
  • Henry Ford Wyandotte HospitalWyandotte, United StatesTaking people
  • University of Michigan Health - WestWyoming, United StatesTaking people
  • Fairview Lakes Medical CenterWyoming, United StatesNo longer taking part
  • North Star Lodge Cancer Center at Yakima Valley Memorial HospitalYakima, United StatesTaking people
  • Providence Regional Cancer System-YelmYelm, United StatesNo longer taking part
  • York HospitalYork Village, United StatesTaking people
  • Rush-Copley Healthcare CenterYorkville, United StatesNo longer taking part
  • Saint Elizabeth Youngstown HospitalYoungstown, United StatesTaking people
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor CampusYpsilanti, United StatesTaking people
  • Huron Gastroenterology PCYpsilanti, United StatesNo longer taking part
  • Genesis Healthcare System Cancer Care CenterZanesville, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
ECOG-ACRIN Cancer Research Group
Trial code
NCT03937635
Record updated
19 August 2026
Original description
This phase III trial studies how well lenalidomide and dexamethasone works with or without daratumumab in treating patients with high-risk smoldering myeloma. Drugs used in chemotherapy, such as lenalidomide and dexamethasone, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Immunotherapy with monoclonal antibodies, such as daratumumab, may induce changes in the body's immune system and may interfere with the ability of tumor cells to grow and spread. Giving lenalidomide and dexamethasone with daratumumab may work better in treating patients with smoldering myeloma.Read full original descriptionShow less

Daratumumab to Enhance Therapeutic Effectiveness of Revlimid in Smoldering Myeloma (DETER-SMM)

This phase III trial studies how well lenalidomide and dexamethasone works with or without daratumumab in treating patients with high-risk smoldering myeloma. Drugs used in chemotherapy, such as lenalidomide and dexamethasone, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Immunotherapy with monoclonal antibodies, such as daratumumab, may induce changes in the body's immune system and may interfere with the ability of tumor cells to grow and spread. Giving lenalidomide and dexamethasone with daratumumab may work better in treating patients with smoldering myeloma.

Inclusion: Patients must be diagnosed with asymptomatic high-risk smoldering multiple myeloma (SMM) within the past 12 months. High-risk is defined by the presence of 2 or more of the following factors:; Abnormal serum free light chain ratio of involved to uninvolved >20, but less than 100 if the involved FLC is >= 10 mg/dL by serum free light chain (FLC) assay; Serum M-protein level >= 2 gm/dL; Presence of t(4;14) or del 17p, del 13q or 1q gain by conventional cytogenetics or fluorescence in situ hybridization (FISH) studies; >20% plasma cells on biopsy or aspirate; Bone marrow aspirate and/or biopsy is required to be performed within 42 days prior to randomization and must demonstrate 10-59% clonal plasma cells; >= 1 g/dL on serum protein electrophoresis (within 28 days prior to randomization); >= 200 mg of monoclonal protein on a 24 hour urine protein electrophoresis (within 28 days prior to randomization); NOTE: In the rare situation where the serum protein electrophoresis (SPEP) is felt to be unreliable, then quantitative immunoglobulin levels on nephelometry or turbidometry can be accepted; SPEP, urine protein electrophoresis (UPEP), and serum FLC are required to be performed within 28 days prior to randomization; NOTE: UPEP (on a 24-hour collection) is required; no substitute method is acceptable. Urine must be followed monthly if the baseline urine M-spike is >= 200 mg/24 hour (hr), and urine in addition to serum must be followed in order to confirm a very good partial response (VGPR) or higher response; Patients must have no lytic lesions, no known plasmacytoma, and no unexplained hypercalcemia (i.e., > 11 mg/dL or 1mg/dL above upper limit of normal [ULN]); Hemoglobin >= 11 g/dL (within 28 days prior to randomization); Platelet count >= 100,000 cells/mm\^3 (within 28 days prior to randomization); Absolute neutrophil count >= 1500 cells/mm\^3 (within 28 days prior to randomization); Calculated creatinine clearance >= 30 mL/min (within 28 days prior to randomization); Bilirubin =< 1.5 mg/dL (within 28 days prior to randomization); Serum glutamate pyruvate transaminase (SGPT) (alanine aminotransferase [ALT]) and serum glutamic oxaloacetic transaminase (SGOT) (aspartate aminotransferase [AST]) =< 2.5 times the upper limit of normal (within 28 days prior to randomization); Patients must not have any prior or concurrent systemic or radiation therapy for the treatment of myeloma. Patients must also not have contraindication to deep vein thrombosis (DVT) prophylaxis/aspirin; Patients must not have more than one focal marrow lesion on magnetic resonance imaging (MRI) of either pelvis or spine. Patients with indwelling pacemakers and/or ICD (implantable cardioverter-defibrillator) that is known or suspected to be MRI incompatible will be excused from this test; Concurrent use of erythropoietin is not allowed while on study therapy; Prior or glucocorticosteroid therapy for the treatment of multiple myeloma is not permitted. Prior systemic glucocorticosteroid use for the treatment of non-malignant disorders is permitted; concurrent use after registration on the study should be restricted to the equivalent of prednisone 10 mg per day. Prior or concurrent topical or localized glucocorticosteroid therapy to treat non-malignant comorbid disorders is permitted; Patients must not have active, uncontrolled seizure disorder. Patients must not have had a seizure in the last 6 months; Patients must not have uncontrolled intercurrent illness including uncontrolled hypertension, symptomatic congestive heart failure, unstable angina, uncontrolled cardiac arrhythmia, uncontrolled psychiatric illness or social situation that would limit compliance with the study, or a prior history of Stevens Johnson syndrome; Patient must have an Eastern Cooperative Oncology Group (ECOG) performance status 0, 1, or 2; Patients with monoclonal gammopathy of undetermined significance are not eligible; Patients must not have grade 2 or higher peripheral neuropathy per CTCAE; Patients must not have active, uncontrolled infection; Patients may have a history of current or previous deep vein thrombosis or pulmonary embolism but are required to take some form of anti-coagulation as prophylaxis if they are not currently on full-dose anticoagulation; Patients should not have New York Heart Association classification III or IV heart failure at baseline; Patients with a history of prior malignancy are eligible provided they were treated with curative intent and have been free of disease for the time period considered appropriate for cure of the specific cancer. For most diseases this time frame is 5 years; Patients must agree to register into the mandatory Risk Evaluation and Mitigation Strategy (REMS) program and be willing and able to comply with the requirements of REMS; Women must not be pregnant due to potential harm to the fetus from daratumumab and lenalidomide. All females of childbearing potential (FCBP) must have a blood test or urine study with a sensitivity of at least 25 mIU/mL within 10-14 days prior to the first dose of lenalidomide and again within 24 hours prior to the first dose of lenalidomide. FCBP must also agree to ongoing pregnancy testing while on treatment. A female of childbearing potential is any woman, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has achieved menarche at some point, 2) has not undergone a hysterectomy or bilateral oophorectomy, or 3) has not been naturally postmenopausal (amenorrhea following cancer therapy does not rule out childbearing potential) for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months); Females of childbearing potential (FCBP) must either abstain from sexual intercourse for the duration of their participation in the study or agree to use TWO acceptable methods of birth control, one highly effective method and one additional effective method AT THE SAME TIME for 1) at least 28 days before starting study treatment; 2) while participating in the study; 3) during dose interruptions; and 4) for at least 28 days after the last dose of protocol treatment (FCBP who are assigned to Arm A and receive daratumumab must extend this contraception requirement to 3 months after the last dose of protocol treatment). Women must also agree to not breastfeed during this same time period. Men must agree to either abstain from sexual intercourse for the duration of their participation in the study or use a latex condom during sexual contact with a FCBP while participating in the study and for 28 days after the last dose of protocol treatment even if they have had a successful vasectomy. Men must also agree to abstain from donating sperm while on study treatment and for 28 days after the last dose of protocol treatment even if they have had a successful vasectomy. Both women and men must both agree to abstain from donating blood during study participation and for at least 28 days after the last dose of protocol treatment; Human immunodeficiency virus (HIV)+ patients with undetectable HIV viral loads tested within 6 months are eligible; Patients should not have a history of allergic reactions attributed to compounds of similar chemical or biologic composition to daratumumab, lenalidomide, or dexamethasone; Patients must not have known chronic obstructive pulmonary disease (COPD) with a forced expiratory volume in 1 second (FEV1) <50% of predicted normal or known moderate or severe persistent asthma within 2 years prior to randomization.

ClinicalTrials.gov NCT03937635