Checking whether some type 1 diabetes diagnoses are actually inherited diabetes
Studies young people diagnosed with type 1 diabetes to find missed inherited forms.
Plain-language title generated from the registry record
Registry title: Monogenic Diabetes Misdiagnosed as Type 1
Key facts
- Where
- Montreal, CanadaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people diagnosed with diabetes before age 25, labelled as type 1 or an undetermined type. It checks for a single-gene (monogenic) form of diabetes.
- Age
- From 1 Day to 25 Years
- Sex
- All sexes can join.
- Disease stage
- Diabetes diagnosed under the age of 25, as type 1 or undetermined type.
- Biomarker or test result
- People who already had a positive type 1 diabetes autoantibody test cannot join.
Main reasons for not taking part
- Existing type 1 diabetes autoantibody test with a positive result
Read by machine on 9 November 2026.
Where in Canada
- The Montreal Children's HospitalMontreal, CanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- McGill University Health Centre/Research Institute of the McGill University Health Centre
- Trial code
- NCT03988764
- Record updated
- 10 December 2024
- Original description
The study has two aims:Read full original descriptionShow less
Accurate Diagnosis of Diabetes for Appropriate Management
The study has two aims:
1. To (1a) determine the frequency of monogenic diabetes misdiagnosed as type 1 diabetes (T1D) and (2) to define an algorithm for case selection. 2. To discover novel genes whose mutations cause monogenic diabetes misdiagnosed as T1D.
Inclusion: Diagnosis of diabetes under the age of 25 as either type 1 or undetermined type.
Exclusion: Existing T1D autoantibody testing with a positive result.