Type 1 diabetes trials in Canada

In Canada 51 Also abroad 537

51 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
Where
Calgary, Guelph, Hamilton, Joliette, Montreal, Stouffville, Surrey, Toronto, Vancouver
Age
18 years and over
People
500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07776509 · EU 2025-523295-23-00
Phase 3Taking people
A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults
Where
Calgary, Edmonton, Vancouver
Age
1 year to 35 years
People
150 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07222137 · EU 2025-521797-34-00
Phase 3Taking people
A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)
Where
Calgary, Chicoutimi, Edmonton, London, Ottawa, Québec, Vancouver
Age
1 year to 35 years
People
300 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07222332 · EU 2025-522170-36-00
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
Where
Brampton, Calgary, Guelph, Hamilton, Mississauga, Moncton, Montreal, New Westminster, North York, Québec, Saint-Charles-Borromée, Scarborough Village, Sherbrooke, Stoney Creek, Stouffville, Surrey, Toronto, Truro, Victoria
Age
18 years and over
People
2,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07784725 · EU 2025-523379-41-00
Phase 2/3Taking people
Lean Mass Changes With Semaglutide in Adults With Type 1 Diabetes and Overweight/Obesity.
Where
Montreal
Age
18 years to 65 years
People
40
Run by
McGill University Health Centre/Research Institute of the McGill University Health Centre
See details and how to joinNCT07891156
Phase 3Taking people
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes
Where
Calgary, Halifax, Ottawa, Vancouver
Age
1 year to 25 years
People
723 worldwide
Run by
Sanofi
See details and how to joinNCT07088068
No phaseTaking people
The diabEAT Study: Insulin dElivery Technologies And eaTing Behaviours in People With Type 1 Diabetes
Where
Montreal
Age
12 years and over
People
106
Run by
McGill University
See details and how to joinNCT07348432
Phase 1/2Taking people
VV-14300 for the Treatment of Type 1 Diabetes
Where
Toronto
Age
18 years to 65 years
People
29 worldwide
Run by
Kriya Therapeutics, Inc.
See details and how to joinNCT07831798
No phaseNot yet taking people in Canada
Functional Mobility and Resistance Exercise for Postmenopausal Females With Type 1 Diabetes
Where
Edmonton, Hamilton, Montreal
Age
50 years and over
People
63
Run by
Institut de Recherches Cliniques de Montreal
See details and how to joinNCT07851662
Phase 3Taking people
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Where
Brampton, Calgary, Guelph, Halifax, Hamilton, Kelowna, London, Moncton, Montreal, Pointe-Claire, Québec, Sarnia, Surrey, Sydney, Toronto, Victoria
Age
18 years and over
People
2,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07564414 · EU 2025-522488-14-00
Phase 2Taking people
Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus
Where
Vancouver
Age
8 years to 45 years
People
66 worldwide
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT07142252
Phase 3Taking people
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
Where
Edmonton, Montreal, Toronto, Vancouver
Age
18 years to 65 years
People
57 worldwide
Run by
Vertex Pharmaceuticals Incorporated
See details and how to joinNCT04786262 · EU 2024-513929-23-00
Phase 3Taking people
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
Where
Calgary, Edmonton, Kelowna, Red Deer, Sarnia, Stouffville, Sydney, Terrebonne, Toronto
Age
45 years and over
People
1,778 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07797335
Phase 1Not yet taking people in Canada
ENCRT-103-hPI: Evaluation of an Immune-protected ENCRT-103-hPI Containing Primary Human Islets in Adults With Type 1 Diabetes, With and Without Standard-of-care Portal Vein Islet Infusion.
Where
Toronto, Vancouver
Age
18 years to 75 years
People
10
Run by
Encellin
See details and how to joinNCT07680673
No phaseNot yet taking people in Canada
NO-Meal Announcement in Automated Insulin Delivery (Open-source and Commercial) Systems
Where
Montreal
Age
18 years and over
People
33
Run by
Institut de Recherches Cliniques de Montreal
See details and how to joinNCT07758647
No phaseEnrolling by invitation
Intelligent Care Platform - Quasi-Experimental Trial
Where
Vancouver
Age
3 years to 18 years
People
80
Run by
University of British Columbia
See details and how to joinNCT07712809
No phaseTaking people
Exercise and the Menstrual Cycle in Type 1 Diabetes
Where
Edmonton
Age
18 years to 50 years
People
15
Run by
University of Alberta
See details and how to joinNCT05188014
Early phase 1Taking people
Simultaneous Measurement and Responsive Treatment - Part 2
Where
Toronto
Age
18 years and over
People
40
Run by
ClinSurge Research
See details and how to joinNCT07655076
Phase 2Taking people
Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes
Where
Toronto
Age
18 years and over
People
60 worldwide
Run by
University of Washington
See details and how to joinNCT05822609
No phaseTaking people
Type 1 Diabetes, Exercise and Mentoring Trial
Where
Mississauga, Winnipeg
Age
13 years to 17 years
People
60
Run by
University of Manitoba
See details and how to joinNCT06296992
Phase 2/3Taking people
A Clinical Trial Using Tirzepatide to Help Adults With Type 1 Diabetes Automatically Control Their Blood Sugar
Where
Montreal
Age
18 years and over
People
105 worldwide
Run by
McGill University Health Centre/Research Institute of the McGill University Health Centre
See details and how to joinNCT07284511
No phaseTaking people
Fasted Exercise Training in Type 1 Diabetes (FED-T1D)
Where
Edmonton
Age
18 years to 55 years
People
20
Run by
University of Alberta
See details and how to joinNCT06748963
No phaseTaking people
Prebiotics in Patients With Type 1 Diabetes
Where
Calgary, Edmonton, Saskatoon
Age
7 years and over
People
144
Run by
University of Calgary
See details and how to joinNCT04963777
Phase 2Taking people
The Efficacy, Mechanism & Safety of Sodium Glucose Co-Transporter-2 Inhibitor & Glucagon-Like Peptide 1 Receptor Agonist Combination Therapy in Kidney Transplant Recipients
Where
Toronto
Age
18 years and over
People
20
Run by
University Health Network, Toronto
See details and how to joinNCT05938712
No phaseEnrolling by invitation
Diabetes Transition Coordinator Study
Where
Calgary
Age
17 years to 18 years
People
324
Run by
University of Calgary
See details and how to joinNCT06300047