Tests a near-infrared brain scanner to measure depression in adults
Tests a brain-imaging device to help measure depression in adults with major depression.
Plain-language title generated from the registry record
Registry title: Near Infrared Spectroscopy (NIRS) for Assessment of Depression
Key facts
- Where
- San Francisco, United StatesSee the site
Where in United States
- San Francisco Veterans Affairs Medical CenterSan Francisco, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of California, San Francisco
- Trial code
- NCT04061148
- Record updated
- 11 September 2026
- Original description
Develop a NIRSIT testing protocol that can be administered in the diagnostic setting and reliably distinguishes the symptoms and severity of depression, with the help of repeated measure (up to five visits per subject) comparison of patients being treated for Major Depressive Disorder with control, non-depressed subjects.Read full original descriptionShow less
Clinical Testing of Near Infrared Spectroscopy (NIRS) for Quantitative Assessment of Depression
Develop a NIRSIT testing protocol that can be administered in the diagnostic setting and reliably distinguishes the symptoms and severity of depression, with the help of repeated measure (up to five visits per subject) comparison of patients being treated for Major Depressive Disorder with control, non-depressed subjects.
Inclusion: All subjects who sign informed consent; Controls: Volunteers over 18 years of age who are not depressed; Patients over 18 years of age with a diagnosis of Major Depressive Disorder, receiving clinical therapy at SFVAMC.
Exclusion: Exclusion criteria for depressed patients: 1.Psychotic disorders like schizophrenia 2.Major neurocognitive disorders such as Alzheimer's disease and other dementias 3.Neurologic disorders with anatomic lesions including traumatic brain injury, stroke, tumor and arteriovenous malformation 4.Not receiving clinical therapy for depression at SFVAMC'; Exclusion criteria for control subjects: 1.Depression 2.Anxiety, psychotic, substance abuse, mood and personality disorders 3.Major neurocognitive disorders such as Alzheimer's disease and other dementias 4.Neurologic disorders with anatomic lesions including traumatic brain injury, stroke, tumor and arteriovenous malformation; Subjects who cannot sign informed consent.