Testing spinal cord stimulation to activate fat tissue in adults with obesity
Tests a spinal electrode device in adults with obesity or diabetes.
Plain-language title generated from the registry record
Registry title: Brown Adipose Tissue Activation by Spinal Cord Stimulation
Key facts
- Where
- Portland, United StatesSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 21-70 with long-lasting nerve pain in the leg and back who already plan to have spinal cord stimulation for pain. Their BMI must be 25-45.
- Age
- 21-70 years
- Sex
- All sexes can join.
- Disease stage
- Persistent neuropathic (nerve) leg and back pain. BMI of 25-45.
- Earlier treatment
- Must already be planning spinal cord stimulation (SCS) for pain. Must not have had an SCS trial for pain before.
Main reasons for not taking part
- Not considering SCS for pain
- Taking beta blockers
- Weight change of more than 5% in the last 3 months
- Habitual tobacco use or habitual excessive alcohol use
- Pregnancy
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 21 and 70 years old?
Source: NCT04326192, who can take part
Where in United States
- Oregon Health Science UniversityPortland, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Oregon Health and Science University
- Trial code
- NCT04326192
- Record updated
- 25 August 2026
- Original description
The objective of this study is to investigate and utilize spinal cord stimulation (SCS) as an effective approach to eliciting weight loss and potentially alleviating Type 2 diabetes mellitus (DM), as evidenced by increasing metabolism of adipose tissue.Read full original descriptionShow less
Brown Adipose Tissue Activation by Spinal Cord Stimulation
The objective of this study is to investigate and utilize spinal cord stimulation (SCS) as an effective approach to eliciting weight loss and potentially alleviating Type 2 diabetes mellitus (DM), as evidenced by increasing metabolism of adipose tissue.
Inclusion: Age: 21-70 years; Persistent neuropathic leg and back pain; Subjects who are already planning to undergo SCS for pain; Subjects who have not received a prior SCS trial for pain; Subjects with a BMI of 25-45, using formula; weight (lb) / [height (in)]2 x 703.
Exclusion: Not considering SCS for pain; Forensic patient; Taking beta blockers; Weight change > 5% within last 3 months; Habitual tobacco use; Habitual excessive alcohol use; Pregnancy; Decisionally impaired adults; Children; Neonates; Subjects with a BMI of <25 or >45.