Obesity trials in United States

In United States 744 Also abroad 1939

744 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Gut Microbiota in Metabolic Surgery
Where
Nashville
Age
21 years to 65 years
People
300
Run by
Vanderbilt University Medical Center
See details and how to joinNCT05000996
Phase 2Not yet taking people in United States
Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity
Where
Bethesda
Age
18 years to 65 years
People
60
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT05713799
No phaseNot yet taking people in United States
Assessing the Impact of Perceptions of Unpredictability on Objective Measures of Food Consumption and Metabolism
Where
Phoenix
Age
18 years to 60 years
People
110
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT06690294
No phaseTaking people
Adapting and Assessing the Feasibility of a Telehealth Diabetes Prevention Program for Hispanic Adolescents
Where
Houston
Age
14 years to 16 years
People
40
Run by
Baylor College of Medicine
See details and how to joinNCT06943001
No phaseTaking people
PATHS-UP Health Behavior Self-monitoring Mobile App for Adolescents
Where
Houston
Age
12 years to 18 years
People
30
Run by
Baylor College of Medicine
See details and how to joinNCT06959901
Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Where
Anniston, Baltimore, Bellaire, Birmingham, Boston, Brownsville, Buffalo, Clarksville, Corpus Christi, Dallas, Dayton, Gulfport, Gurnee, Honolulu, Houston, Irvine, Louisville, McAllen, Milwaukee, Minneapolis, Myrtle Beach, Nashville, Needham, New Haven, New Orleans, Portland, Salt Lake City, San Antonio, San Diego, Schaumburg, Shavano Park, Sioux Falls, Skokie, Southlake, Springfield, Tucson, Tulsa, Union City, Walnut Creek, West Chester
Age
18 years and over
People
2,000 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351045 · EU 2025-523104-71-00
Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Where
Blackfoot, Brownsville, Clearwater, Columbia, Columbus, Dallas, Decatur, Edinburg, Guntersville, Houston, Irvine, Kansas City, Lake Charles, Lake Forest, Long Beach, Manassas, Metairie, Montclair, Morehead City, New Orleans, Norco, Norman, North Charleston, Oklahoma City, Olive Branch, Pasadena, Pembroke Pines, Pittsburgh, Port Orange, Rancho Cucamonga, Redmond, San Antonio, Sioux Falls, Springfield, Spring Valley, St. Petersburg, Suffolk, Tomball, Tucson, Tulsa, Union City, Washington D.C., Winston-Salem
Age
18 years and over
People
1,600 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351058 · EU 2025-523106-32-00
No phaseNot yet taking people in United States
Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and Adults
Where
Bethesda
Age
8 years to 65 years
People
1,000
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT07388537
No phaseNot yet taking people in United States
A Natural History of Genetic and Environmental Predictors of Pubertal Timing Among Youth With Obesity
Where
Research Triangle Park
Age
5 years to 12 years
People
400
Run by
National Institute of Environmental Health Sciences (NIEHS)
See details and how to joinNCT07437976
Phase 1Taking people
A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.
Where
Brooklyn, Glendale
Age
18 years to 65 years
People
104 worldwide
Run by
AstraZeneca
See details and how to joinNCT07511205
Phase 4Taking people
Semaglutide in Youth With Autism Spectrum Disorder
Where
Cincinnati
Age
12 years to 18 years
People
42
Run by
Children's Hospital Medical Center, Cincinnati
See details and how to joinNCT07770152
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
Where
Beltsville, Champaign, Chicago, Columbus, Escondido, Fargo, Franklin, Houston, Jacksonville, Kansas City, Las Vegas, Lincoln, Manassas, Oxon Hill, Portland, Renton, Smithfield, Somerset, Statesville, Stockbridge, Walnut Creek, Woodstock
Age
18 years and over
People
500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07776509 · EU 2025-523295-23-00
Phase 3Taking people
Home Self-administration of Maridebart Cafraglutide With Autoinjector in Adults Living With Obesity or Overweight
Where
Bowie, Chickasha, Columbus, Dallas, Denison, DeSoto, Greenville, Houston, Johns Creek, McKinney, Meridian, Miami, Morehead City, North Richland Hills, Oak Brook, Orlando, Rochester, San Diego, The Villages, Woodstock
Age
18 years to 99 years
People
230 worldwide
Run by
Amgen
See details and how to joinNCT07871409
Phase 1Not yet taking people in United States
A Study to Investigate the Effect of Injection Site and Ethnicity on KAI-4729 Pharmacokinetics in Non-Asian and Asian Participants Living With Obesity or Overweight
Where
Anaheim
Age
18 years to 55 years
People
60
Run by
Kailera
See details and how to joinNCT07924761
No phaseNot yet taking people in United States
Improving Labor Management for Patients With Severe Obesity Using Abdominal Pannus Retraction
Where
Milwaukee
Age
18 years and over
People
100
Run by
Medical College of Wisconsin
See details and how to joinNCT07924800
No phaseTaking people
PM2.5 Exposure, Obesity, and Cardiovascular Health
Where
East Lansing
Age
21 years and over
People
20
Run by
Michigan State University
See details and how to joinNCT07924839
No phaseTaking people
Scalable TELeheaLth Cancer CARe: The STELLAR Program to Treat Cancer Risk Behaviors
Where
Chicago
Age
18 years and over
People
1,500
Run by
Northwestern University
See details and how to joinNCT05687604
No phaseTaking people
Metabolic Health, Bones and Nuts During Weight Loss in Adults
Where
New Brunswick
Age
50 years to 75 years
People
44
Run by
Rutgers, The State University of New Jersey
See details and how to joinNCT06949280
Phase 3Taking people
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
Where
Austin, Baton Rouge, Beaver, Canton, Chandler, Chickasha, Chula Vista, DeSoto, Duncansville, Edinburg, Gainesville, Hialeah, Houston, Johns Creek, Kapolei, Las Vegas, Lenexa, Margate, McAllen, McKinney, Meridian, Miami, Missoula, Morehead City, Mt. Dora, New York, North Richland Hills, Oklahoma City, Orlando, Palm Springs, Pelham, Port Orange, Raleigh, Redmond, Rialto, Ridgeland, Rochester, San Antonio, San Diego, Santa Ana, Skokie, Southfield, Springfield, Sun City, Sun City West, The Villages, Tomball, Troy, Union City, Wilmington, Woodstock
Age
18 years to 99 years
People
300 worldwide
Run by
Amgen
See details and how to joinNCT07575399
Phase 2Taking people
Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes
Where
Chicago, Doral, Fort Myers, Greenville, Hialeah, Inverness, Jacksonville, Lexington, Maitland, Mobile, New York, Oak Brook, Omaha, Rochester, St. Petersburg, The Villages, Walnut Creek, Waterbury, Wichita, Winter Park
Age
18 years and over
People
360
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07685808
Phase 2Not yet taking people in United States
Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving Leukemia and Lymphoma
Where
Memphis
Age
12 years to 24 years
People
100
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT07790913
No phaseTaking people
An Online Intuitive Eating Program for Pregnant Women With Obesity to Support Well-Being
Where
San Diego
Age
18 years and over
People
80
Run by
San Diego State University
See details and how to joinNCT07792837
Phase 1Taking people
A Study to Learn How Different Forms of the Study Medicine Called Berobenatide is Taken up Into the Blood in Adults With Overweight or Obesity
Where
Anaheim
Age
18 years and over
People
144
Run by
Pfizer
See details and how to joinNCT07876531 · EU 2025-524803-65-00
Phase 3Taking people
A Study to Learn About the Monthly Dosing Study Medicine Called Berobenatide in Adults With Breathing Problems During Sleep and Overweight or Obesity Who Do Not Use a Breathing Machine (PAP) (VESPER-OSA 2)
Where
Bradenton, Cullman, Maplewood, Tomball
Age
18 years and over
People
258
Run by
Pfizer
See details and how to joinNCT07881757
No phaseEnrolling by invitation
Bariatric Surgery Registry
Where
Richmond
Age
12 years to 75 years
People
8,000
Run by
Virginia Commonwealth University
See details and how to joinNCT01055054