Follow-up study of people with early blood changes linked to myelodysplastic syndromes
Observes how early blood changes linked to myelodysplastic syndromes develop over time in adults.
Plain-language title generated from the registry record
Registry title: Follow-up Study of ICUS and CCUS Patients
Key facts
- Where
- Suzhou, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with low blood counts that last at least 4 months and do not meet the minimal diagnostic criteria of myelodysplastic syndromes (MDS).
- Age
- 18 years or older
- Sex
- All sexes can join.
- Disease stage
- Low counts of red blood cells, neutrophils or platelets (one or more), lasting at least 4 months, without the minimal diagnostic criteria of MDS.
Main reasons for not taking part
- Low blood counts that another blood disease or non-blood disease can explain
Read by machine on 12 November 2026.
Where in China
- The First Affliated Hospital of Soochow UniversitySuzhou, ChinaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- The First Affiliated Hospital of Soochow University
- Trial code
- NCT04428489
- Record updated
- 29 December 2025
- Original description
The proposed minimal diagnostic criteria for myelodysplastic syndromes (MDS) and potential pre-MDS conditions has been released by an international consensus group. Based on the criteria, patients with persistent cytopenia could be diagnosed with MDS, CCUS and ICUS. However, the process and outcome of pre-MDS conditions (CCUS, ICUS) is still to be characterized in Chinese population. We design this prospective observational study to explore the disease process and outcome in ICUS and CCUS patients.Read full original descriptionShow less
A Follow-up Observational Study of ICUS and CCUS Patients
The proposed minimal diagnostic criteria for myelodysplastic syndromes (MDS) and potential pre-MDS conditions has been released by an international consensus group. Based on the criteria, patients with persistent cytopenia could be diagnosed with MDS, CCUS and ICUS. However, the process and outcome of pre-MDS conditions (CCUS, ICUS) is still to be characterized in Chinese population. We design this prospective observational study to explore the disease process and outcome in ICUS and CCUS patients.
Inclusion: Patients with cytopenia of any degree in one or more lineages: erythrocytes, neutrophils, or platelets. And the cytopenia has to be persistent (≥ 4 months) and lacking minimal diagnostic criteria of MDS.
Exclusion: Patients with cytopenia which could be explained by any other hematologic or non-hematologic disease.