Brain scans to predict outcomes of surgery for hard-to-treat epilepsy in children
Studies resting brain scans to predict outcome of surgery in children with drug-resistant epilepsy.
Plain-language title generated from the registry record
Registry title: RESting-state Functional MRI for Prediction of Post-surgical Prognosis In Pediatric Drug-Resistant Epilepsy
Key facts
- Where
- Paris, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 6 and 18 years old?
Source: NCT04451278, who can take part
Where in France
- Fondation A. de RothschildParis, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Fondation Ophtalmologique Adolphe de Rothschild
- Trial code
- NCT04451278
- Record updated
- 5 January 2026
- Original description
Resting-state functional MRI (r-fMRI) has emerged in recent years to analyze resting networks. It allows, without active participation of the patients, to identify and analyze the different functional brain networks. The analysis of r-fMRI can be done thanks to the graph theory, which is based on the based on the calculation of quantifiable parameters applied to the functional network studied, making it possible to assess its effectiveness.Read full original descriptionShow less
RESting-state Functional MRI for Prediction of Post-surgical Prognosis In Pediatric Drug-Resistant Epilepsy
Resting-state functional MRI (r-fMRI) has emerged in recent years to analyze resting networks. It allows, without active participation of the patients, to identify and analyze the different functional brain networks. The analysis of r-fMRI can be done thanks to the graph theory, which is based on the based on the calculation of quantifiable parameters applied to the functional network studied, making it possible to assess its effectiveness.
To the knowledge of the investigators, no study has used graph theory applied to r-fMRI data in order to obtain parameters useful for the useful parameters for the individual prognosis of children who have to be operation for drug-resistant lesional epilepsy.
Inclusion: Patient aged between 6 and 18 years; Receiving an MRI for lesional drug-resistant epilepsy; Affiliated or beneficiary of a social security plan; Whose parents or guardians have received information about the study and have given their express consent to participate in the study.
Exclusion: History of intracranial surgery; Contraindication to absolute or relative MRI (in particular, pregnant or breastfeeding women); MRI performed under general anesthesia.