Follows adults with prediabetes or type 2 diabetes to study mood and thinking
Observes adults with prediabetes or type 2 diabetes over time for mood and thinking changes.
Plain-language title generated from the registry record
Registry title: The Sunnybrook Type 2 Diabetes Study
Key facts
- Where
- Toronto, CanadaSee the site
Where in Canada
- Sunnybrook Research InstituteToronto, CanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Sunnybrook Health Sciences Centre
- Trial code
- NCT04455867
- Record updated
- 12 April 2023
- Original description
The Sunnybrook Type 2 Diabetes Study (S2DS) is a prospective observational study of people with prediabetes or Type 2 Diabetes Mellitus (T2DM), that aims to understand the aetiologies, manifestations, and clinical consequences of mood and cognitive complications. The study recruits from the services at Sunnybrook Health Sciences Centre and from the neighbouring University Health Network Toronto Rehabilitation Institute Cardiac Rehabilitation Program.Read full original descriptionShow less
The Sunnybrook Type 2 Diabetes Study
The Sunnybrook Type 2 Diabetes Study (S2DS) is a prospective observational study of people with prediabetes or Type 2 Diabetes Mellitus (T2DM), that aims to understand the aetiologies, manifestations, and clinical consequences of mood and cognitive complications. The study recruits from the services at Sunnybrook Health Sciences Centre and from the neighbouring University Health Network Toronto Rehabilitation Institute Cardiac Rehabilitation Program.
Inclusion: Have at least one of the following: high HbA1c, impaired fasting glucose (IFG), impaired glucose tolerance (IGT), but not yet diagnosed with Type 2 diabetes or have a diagnosis of Type 2 diabetes; Be able to communicate in English; Be 18 years of age or older.
Exclusion: Have a prior diagnosis of bipolar disorder or schizophrenia; Have a prior diagnosis of a neurological and/or neurodegenerative disorder; Have a current substance use disorder or a previous substance use disorder diagnosed within the last 5 years (excluding nicotine); Participants that have a medical device that would interfere with placement of portable sleep monitor equipment i.e. Participant requires O2 therapy and uses nasal prongs; Current cancer diagnosis; Significant pulmonary disease (e.g. asthma, pulmonary fibrosis, emphysema, chronic obstructive pulmonary disease, pulmonary vascular disease, pleural disorders, pneumonia); Participants that have a condition that may compromise accuracy of the HSAT results i.e. moderate-severe pulmonary disease or congestive heart failure; Pregnancy; Inability to give informed consent; Poor score on the Mini Mental State Examination (MMSE); Contraindications to SHSC's MRI safety protocol; Participants that do not meet the inclusion/exclusion criteria of the main study; Use of medical equipment that would interfere with the placement of the CVR mask; Participants that do not meet the criteria for the MRI sub-study; Participants that do not meet the inclusion/exclusion criteria of the main study.