Type 2 diabetes trials in Canada

In Canada 80 Also abroad 1196

80 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Where
Brampton, Calgary, Hamilton, Québec, Sarnia, Surrey, Trois-Rivières
Age
18 years and over
People
2,000 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351045 · EU 2025-523104-71-00
Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Where
Brampton, Calgary, Greater Sudbury, Montreal, Québec, Sherbrooke, Toronto, Vancouver
Age
18 years and over
People
1,600 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351058 · EU 2025-523106-32-00
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
Where
Calgary, Guelph, Hamilton, Joliette, Montreal, Stouffville, Surrey, Toronto, Vancouver
Age
18 years and over
People
500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07776509 · EU 2025-523295-23-00
Phase 3Taking people
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
Where
Hamilton, Moncton, Surrey, Toronto
Age
18 years and over
People
954 worldwide
Run by
Pfizer
See details and how to joinNCT07595549 · EU 2026-525318-75-00
Phase 3Taking people
Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 Diabetes
Where
Vancouver
Age
18 years and over
People
1,300 worldwide
Run by
Amgen
See details and how to joinNCT07866066 · EU 2025-523772-22-00
Phase 2Taking people
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Where
Brampton, Chicoutimi, Hamilton, Longueuil, Moncton, Sarnia, Toronto, Waterloo
Age
18 years to 75 years
People
200 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06897475 · EU 2024-520328-27-00
No phaseTaking people
OBEDIAM: Therapeutic Patient Education in Adults Living With Obesity, Diabetes, and Metabolic Disorders
Where
Québec
Age
18 years to 80 years
People
42
Run by
CHU de Quebec-Universite Laval
See details and how to joinNCT07668661
Phase 3Not yet taking people in Canada
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular Risk
Where
Brampton, Calgary, Halifax, Kelowna, Montreal, Pointe-Claire, Québec, St. John's, Terrebonne, Waterloo
Age
45 years to 64 years
People
3,000 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07900633 · EU 2026-525919-14-00
No phaseTaking people
6-Weeks of Blood Flow Restriction Training on Immune Cell Function and Bioenergetics
Where
Kelowna
Age
19 years to 64 years
People
20
Run by
University of British Columbia
See details and how to joinNCT07676305
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
Where
Brampton, Calgary, Guelph, Hamilton, Mississauga, Moncton, Montreal, New Westminster, North York, Québec, Saint-Charles-Borromée, Scarborough Village, Sherbrooke, Stoney Creek, Stouffville, Surrey, Toronto, Truro, Victoria
Age
18 years and over
People
2,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07784725 · EU 2025-523379-41-00
Phase 3Taking people
A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar
Where
Brampton, Concord, Montreal, Nepean, New Westminster, Québec, Toronto
Age
18 years and over
People
600 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07754461
Phase 2Not yet taking people in Canada
Adding Acetazolamide on Top of SGLT2 Inhibition in Persons With Type 2 Diabetes
Where
Toronto
Age
18 years and over
People
20
Run by
University Health Network, Toronto
See details and how to joinNCT07902726
Phase 3Taking people
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Where
Calgary, Cambridge, Chicoutimi, Courtice, Halifax, Joliette, Kelowna, Laval, London, Mississauga, Moncton, Montreal, Newmarket, New Westminster, North Vancouver, Oshawa, Ottawa, Penticton, Peterborough, Québec, Red Deer, Saint-Lambert, Sarnia, Scarborough Village, Sherbrooke, Stoney Creek, Stouffville, Surrey, Terrebonne, Toronto, Trois-Rivières
Age
18 years and over
People
11,800 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07064473 · EU 2025-521188-11-00
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight
Where
Calgary, Hamilton, Joliette, Markham, Moncton, Montreal, North York, Québec, Sarnia, Scarborough Village, Stoney Creek, Stouffville, Toronto, Trois-Rivières, Truro, Vancouver
Age
18 years and over
People
1,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07784270
Phase 3Taking people
A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus
Where
Guelph, Montreal, Saint-Charles-Borromée, Sarnia, Scarborough Village, Stouffville, Toronto, Vancouver
Age
18 years and over
People
1,200 worldwide
Run by
AstraZeneca
See details and how to joinNCT07662213 · EU 2025-523933-24-00
No phaseTaking people
Technology-Enabled Collaborative Care for Diabetes and Mental Health
Where
Hamilton, Toronto
Age
18 years and over
People
160
Run by
McMaster University
See details and how to joinNCT07181863
Phase 3Taking people
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
Where
Brampton, Calgary, Hamilton, Joliette, Moncton, Montreal, Niagara Falls, North York, Saint-Lambert, Sarnia, Scarborough Village, Stouffville, Terrebonne, Toronto, Truro, Vancouver, Victoria
Age
18 years and over
People
4,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07667803
Phase 2Taking people
Effects of Different Fish Oil Types on Type 2 Diabetes Risk Factors in High-Risk Adults
Where
Montreal
Age
40 years to 70 years
People
84
Run by
May Faraj, PDt, PhD
See details and how to joinNCT07575438
No phaseTaking people
Visceral Adipose Tissue and Liver Changes Associated With Semaglutide in CKD
Where
Edmonton
Age
18 years and over
People
52
Run by
University of Alberta
See details and how to joinNCT07187830
Phase 3Taking people
COLchicine and Non-enteric Coated Aspirin in the Cardiovascular Outcomes Trial of Patients With Type 2 Diabetes
Where
Montreal, Toronto
Age
55 years to 80 years
People
10,000 worldwide
Run by
Montreal Heart Institute
See details and how to joinNCT05633810 · EU 2024-516646-19-00
Phase 3Taking people
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)
Where
Hamilton
Age
18 years to 99 years
People
950 worldwide
Run by
Amgen
See details and how to joinNCT07684144 · EU 2025-524788-19-00
Phase 1/2Taking people
VV-14300 for the Treatment of Type 1 Diabetes
Where
Toronto
Age
18 years to 65 years
People
29 worldwide
Run by
Kriya Therapeutics, Inc.
See details and how to joinNCT07831798
No phaseTaking people
Peel Family Diabetes Prevention Program
Where
Brampton
Age
14 years and over
People
140
Run by
Trillium Health Partners
See details and how to joinNCT07675551
Phase 3Taking people
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Where
Brampton, Calgary, Guelph, Halifax, Hamilton, Kelowna, London, Moncton, Montreal, Pointe-Claire, Québec, Sarnia, Surrey, Sydney, Toronto, Victoria
Age
18 years and over
People
2,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07564414 · EU 2025-522488-14-00
Phase 3Taking people
A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes
Where
Brampton, Courtice, Guelph, Hamilton, Québec, Sarnia, Stoney Creek, Trois-Rivières
Age
18 years and over
People
1,980 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07321886 · EU 2025-523657-34-00