Inhaled Versus Intravenous Milrinone in Severe Lung Artery Pressure During Heart Surgery
Compares inhaled and intravenous milrinone in adults with severe pulmonary hypertension having heart surgery.
Plain-language title generated from the registry record
Registry title: Inhaled and Intravenous Milrinone in Patients With Severe Pulmonary Hypertension
Key facts
- Where
- Zagazig, EgyptSee the site
- Phase
- Phase 4
Where in Egypt
- Zagazig UniversityZagazig, EgyptTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Zagazig University
- Trial code
- NCT04484675
- Record updated
- 30 April 2025
- Original description
The investigator compared difference between inhaled and intravenous milirinone in patiens with severe pulmonary hypertension undergoing cardiac surgeryRead full original descriptionShow less
Comparative Study Between Inhaled and Intravenous Milrinone in Patients With Severe Pulmonary Hypertension Undergoing Cardiac Surgery
The investigator compared difference between inhaled and intravenous milirinone in patiens with severe pulmonary hypertension undergoing cardiac surgery
Inclusion: Patients scheduled to undergo mitral valve surgery by cardiopulmonary bypass with estimated mean pulmonary artery pressure =>55 estimated by using preoperative Doppler echocardiography.
Exclusion: , coagulopathy, and thromboembolic disease treated with anticoagulants; Patients were excluded if they had surgery without CPB, preoperative hemodynamic instability (defined as acute requirement for vasoactive support or mechanical device),Patients with severe LV dysfunction (LV ejection fraction of less than 30% congenital heart disease, a contraindication to transesophageal echocardiography (TEE), emergency surgery or re-do surgeries severe renal or hepatic disease.