Screening Young Children and Parents for Familial High Cholesterol
Checks cholesterol and genes in 1- to 3-year-olds and their parents for familial hypercholesterolemia.
Plain-language title generated from the registry record
Registry title: Child-Parent Familial Hypercholesterolemia Screening
Key facts
- Where
- Chongqing, Hefei, Qidong, Shanghai, Taiyuan, and Ürümqi, ChinaSee the 6 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 1 and 3 years old?
Source: NCT04529967, who can take part
Where in China
- Chongqin Medical University Affiliated Children's HospitalChongqing, ChinaTaking people
- Anhui Provincial Children's HospitalHefei, ChinaTaking people
- Qidong Women and Children HospitalQidong, ChinaTaking people
- Weili YanShanghai, ChinaTaking people
- Shanxi Provincial Children's HospitalTaiyuan, ChinaTaking people
- Urumqi Children's HospitalÜrümqi, ChinaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Children's Hospital of Fudan University
- Trial code
- NCT04529967
- Record updated
- 15 May 2026
- Original description
Child-parent screening for familial hypercholesterolemia has been proposed to identify children and their parent who are carrier of mutations and with high risk for inherited premature coronary artery disease. The investigators assessed the efficacy and feasibility of such screening in primary care practice.Read full original descriptionShow less
Child-Parent Screening of Familial Hypercholesterolemia in Children
Child-parent screening for familial hypercholesterolemia has been proposed to identify children and their parent who are carrier of mutations and with high risk for inherited premature coronary artery disease. The investigators assessed the efficacy and feasibility of such screening in primary care practice.
key scientific questions:
1. The 95th and 99th percentile of finger blood TC in children of 2 years old. 2. Mutations that contribute to high TC status ( serum TC >99th percentiles) compared with international FH48 panel for FH genetic screening.
Inclusion: Receive routine child care; aged 1 - 3 years old ( date of investigate minus date of birth).
Exclusion: It is up to the researcher to decide whether it is suitable to participate in this research.