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Testing sleep apnea treatment before heart rhythm ablation in atrial fibrillation

Tests screening and treating sleep apnea in adults with atrial fibrillation considered for ablation.

Key facts

Who runs it
Hospital San Carlos, Madrid
Where
Madrid, SpainSee the site
Trial code
Registry title
Value of Screening and Treatment of SAHS in the Management of AF Ablation Candidates
Status
Recruiting
People taking part
50 people, planned
Started
5 Nov 2020
Expected to end
31 Dec 2026
Type of study
Interventional, 2 groupsOne group gets no study treatment, for comparison.
Treatments tested
  • Treatment of SAHS
Record updated
15 September 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with paroxysmal or persistent atrial fibrillation that keeps coming back despite heart rhythm medicine, and who have not been diagnosed with sleep apnea-hypopnea syndrome.

Age
18 years or older
Sex
All sexes can join
Disease stage
Paroxysmal or persistent atrial fibrillation that returns despite treatment
Earlier treatment
Must have had at least one class I or III antiarrhythmic drug, with atrial fibrillation coming back anyway

Main reasons for not taking part

  • Younger than 18 years
  • Pregnant women
  • Doubts about being able to do a home respiratory polygraphy
  • Doubts about being able to record heart rhythm with the Kardia system (smartphone needed)
  • Cannot be followed up at the center for at least 1 year

The registry criteria, word for word

Show all 8 criteriaShow less

Who can take part

  • Patients with paroxysmal or persistent atrial fibrillation
  • Recurrent atrial fibrillation despite treatment with at least one class I or III antiarrhythmic
  • No previous diagnosis of apnea-hypopnea syndrome

Who cannot take part

  • Patients <18 years
  • Pregnant women
  • Doubts about the patient's ability to perform a home respiratory polygraphy
  • Doubts about the patient's ability to acquire rhythm records with the Kardia system (smartphone required)
  • Unavailability for follow-up at our center for at least 1 year

Where in Spain

  • Hospital Clínico San CarlosMadrid, SpainContact: Nicasio Pérez-Castellano, MDhPhDTaking people

About the trial

What the trial wants to find out

The present prospective cohort study (not randomized) analyses the value of screening and treatment of SAHS in the management of patients with AF refractory to antiarrhythmics drugs, potentially candidates for ablation.

Read full original descriptionShow less

Patients at low risk of suffering from SAHS will follow conventional management of their AF, according to the usual criteria of the Arrhythmia Unit. Patients with high or intermediate risk of SAHS, will undergo respiratory polygraphy. If the result is positive, they will be treated as standard for this syndrome and their heart rate will be monitored for 3 months. After this, the patient's arrhythmic load will be reevaluated differentiating patients into two groups, those that must be ablated from those that have improved their condition and the clinical criteria is no longer ablation but follow-up.

The 2 groups in the trial

  • Patients with negative diagnosis of SAHSNo study treatment, for comparison

    Patients with low risk or negative diagnosis of SAHS will follow conventional management of their AF, according to the usual criteria of the Arrhythmia Unit

  • Patients with positive diagnosis of SAHSOther group

    Patients with intermediate or high risk of SAHS and positive diagnosis

    Treatment: Treatment of SAHS

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Value of Screening and Treatment of Sleep Apnea-Hypopnea Syndrome in the Management of Atrial Fibrillation Ablation Candidates
Plain-language title
Testing sleep apnea treatment before heart rhythm ablation in atrial fibrillationGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 12 November 2026.
Record updated
15 September 2025