Atrial fibrillation trials in Spain

In Spain 48 Also abroad 724

48 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
Where
A Coruña, Barcelona, Caceres, L'hospitalet De Llobregat, Madrid, Málaga, Murcia, Oviedo, Sanlúcar de Barrameda, Sevilla, Valencia, Villamartín
Age
18 years and over
People
2,628 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07430956 · EU 2025-521618-25-00
No phaseTaking people
AI-Based Tools for Stroke Diagnosis, Treatment and Outcome Prediction: a Multicentre Prospective Observational Study
Where
Barcelona
Age
18 years and over
People
10,000 worldwide
Run by
Hospital Universitari Vall d'Hebron Research Institute
See details and how to joinNCT07924371
Phase 4Not yet taking people in Spain
iSGLT2 in permanent atrial fibrillation, heart failure with preserved ejection fraction and intermediate NT-proBNP values: randomized clinical trial
Where
Badalona, Barcelona, Gijón, Reus, Sabadell
Age
65 years and over
People
125
Run by
Institut D Investigacio Sanitaria Pere Virgili
See details and how to join2026-525968-18-00 · EU 2026-525968-18-00
No phaseTaking people
Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation Therapy
Where
Alicante, Barcelona, Madrid
Age
18 years and over
People
482 worldwide
Run by
Insel Gruppe AG, University Hospital Bern
See details and how to joinNCT05976685
Phase 3Taking people
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation
Where
A Coruña, Albacete, Barcelona, Caceres, Castilleja De La Cuesta, Jaén, L'hospitalet De Llobregat, Madrid, Majadahonda, Málaga, Murcia, Oviedo, Puerto Real, Sanlúcar de Barrameda, Santiago de Compostela, Sevilla, Valencia, Vigo, Villamartín
Age
18 years and over
People
15,364 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07626411 · EU 2025-521617-97-00
No phaseTaking people
OPTION-EMEA Clinical Trial
Where
Salamanca, Valencia, Vigo
Age
18 years and over
People
500 worldwide
Run by
Boston Scientific Corporation
See details and how to joinNCT07349121
No phaseTaking people
Comprehensive LEFt Atrial Appendage Occlusion With Rhythm Restoration
Where
Barcelona, Pamplona
Age
18 years and over
People
240 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT07523620
No phaseTaking people
Evaluation of the FARAFLEX Mapping and Pulsed Field Ablation System in Subjects With Atrial Fibrillation
Where
Pamplona
Age
18 years and over
People
571 worldwide
Run by
Boston Scientific Corporation
See details and how to joinNCT07575269
No phaseTaking people
Pericardiotomy in Cardiac Surgery
Where
Alicante, Madrid
Age
18 years and over
People
1,400 worldwide
Run by
Population Health Research Institute
See details and how to joinNCT06486636
No phaseTaking people
PulseSelect™ PFA Global Registry
Where
Córdoba, Málaga, Salamanca
Age
18 years and over
People
1,950 worldwide
Run by
Medtronic Cardiac Ablation Solutions
See details and how to joinNCT06393920
No phaseTaking people
Safety and Effectiveness of Short-Term Single AntiPlatelet Therapy After Left Atrial Appendage Closure With the LAmbre Device in Patients With Nonvalvular Atrial Fibrillation: A Multinational Real-world Registry
Where
A Coruña, Aravaca, Barcelona, Córdoba, Fuencarral-El Pardo, Gijón, Las Palmas de Gran Canaria, León, L'Hospitalet de Llobregat, Lleida, Madrid, Majadahonda, Málaga, Manises, Palma de Mallorca, Salamanca, Seville, Tarragona, Valencia
Age
18 years to 100 years
People
234
Run by
Fundación EPIC
See details and how to joinNCT06620757
Phase 3Taking people
ReVeRA-301: Etripamil in Atrial Fibrillation Phase 3
Where
Alicante, Barcelona, Gijón, Granada, L'hospitalet De Llobregat, Madrid, Santiago de Compostela, Sevilla, Valencia, Vigo, Zaragoza
Age
18 years and over
People
750 worldwide
Run by
Milestone Pharmaceuticals Inc.
See details and how to joinNCT06716021 · EU 2024-516251-40-01
No phaseTaking people
Left Bundle Branch Area Pacing (LBBAP) PMCF Study
Where
Madrid
Age
18 years and over
People
200 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT07217392
No phaseTaking people
PLAI-AF Trial: Hybrid Endo-epicardial Partial Left Atrial Isolation vs. Endocardial Ablation in Patients With Persistent Atrial Fibrillation
Where
Barcelona
Age
18 years to 75 years
People
80
Run by
Hospital Clinic of Barcelona
See details and how to joinNCT05723536
No phaseTaking people
The Fourth Left Atrial Appendage Occlusion Study
Where
Alicante, Barcelona, Huelva, León, Madrid, Valladolid, Vigo
Age
18 years and over
People
4,000 worldwide
Run by
Hamilton Health Sciences Corporation
See details and how to joinNCT05963698
No phaseTaking people
Genetic Characterization of Patients With Arrhythmia-Induced Cardiomyopathy
Where
Albacete, Ciudad Real, Madrid
Age
18 years and over
People
109
Run by
Hospital Universitario 12 de Octubre
See details and how to joinNCT06896266
No phaseNot yet taking people in Spain
Lattice vs Pentaspline Comparative Evaluation in Persistent AF
Where
Madrid, Valencia
Age
18 years and over
People
250 worldwide
Run by
Mitera Hospital
See details and how to joinNCT07815171
Phase 2/3Taking people
Caffeine Consumption and Rate Control in Permanent Atrial FIBrillation: The CAFIB Trial
Where
Getafe
Age
18 years to 80 years
People
50
Run by
Hospital Universitario Getafe
See details and how to joinNCT07738523
No phaseTaking people
Risk Score of Embolism in Patients With AF Undergoing DOAC Therapy
Where
Barcelona
People
250
Run by
Hospital Universitari Vall d'Hebron Research Institute
See details and how to joinNCT07713537
Phase 3Taking people
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
Where
A Coruna, Almería, Barcelona, Cabra, Granada, Jaén, León, L'hospitalet De Llobregat, Madrid, Málaga, Murcia, Oviedo, Sabadell, Santiago de Compostela, Sevilla, Terrassa, Valencia, Vigo
Age
65 years and over
People
2,500 worldwide
Run by
Anthos Therapeutics, Inc.
See details and how to joinNCT05712200 · EU 2023-503224-66-00
No phaseTaking people
Non-invasive Mapping-Guided Atrial Fibrillation Ablation
Where
Barcelona
Age
18 years and over
People
30
Run by
Hospital Clinic of Barcelona
See details and how to joinNCT07358611
No phaseNot yet taking people in Spain
Pharmacy-based Opportunistic Atrial Fibrillation Screening Integrated With Emergency Services (NUMAPLUS-FA)
Where
Seville
Age
65 years and over
People
380
Run by
Centro de Emergencias Sanitarias 061 Andalucía
See details and how to joinNCT07598903
Phase 3Taking people
Early Treatment of Atrial Fibrillation for Stroke Prevention Trial in Acute STROKE
Where
Badalona, Barcelona, Majadahonda, Valencia, Valladolid, Zaragoza
Age
18 years and over
People
1,746 worldwide
Run by
Universitätsklinikum Hamburg-Eppendorf
See details and how to joinNCT05293080 · EU 2025-521260-35-00
Phase 4Taking people
Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation
Where
Santander
Age
18 years and over
People
3,010 worldwide
Run by
Insel Gruppe AG, University Hospital Bern
See details and how to joinNCT05955365
No phaseTaking people
Lesion Formation With Pulsed Field Versus Cryobaloon Ablation as Assessed by Cardiac Magnetic Resoncance
Where
Barcelona
Age
18 years and over
People
104
Run by
Hospital Clinic of Barcelona
See details and how to joinNCT06220006