Studies brain activity in epilepsy using implanted intracranial electrodes
Records brain electrical activity in adults with focal epilepsy undergoing pre-surgical investigation.
Key facts
- Who runs it
- Institut National de la Santé Et de la Recherche Médicale, France
- Where
- Paris, FranceSee the site
- Trial code
- Registry title
- Multi-level Approach of Brain Activity Using Intracranial Electrodes in Epileptic Patients
- Status
- Recruiting
- People taking part
- 80 people, planned
- Started
- 28 Feb 2021
- Expected to end
- 27 Feb 2031
- Type of study
- Interventional
- Treatments tested
- Intracranial macro-microelectrode recording
- Record updated
- 28 September 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with focal epilepsy that does not respond to drugs. They must be having surgery planning tests with electrodes placed in the brain at one hospital.
- Age
- 18 years and older
- Sex
- All sexes can join.
- Disease stage
- Focal epilepsy that does not respond to drugs (drug-resistant).
Main reasons for not taking part
- Cannot safely have electrodes placed in the brain: current infection, or serious uncontrolled heart, lung, kidney or liver disease
- Higher risk of infection, for example taking drugs that weaken the immune system
- Pregnant or in labour
- Breastfeeding
- Under 18 years old, or an adult under legal protection (guardianship)
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- Patients with focal drug-resistant epilepsy
- Patients who undergo a presurgical evaluation with intracranial electrodes in the videoEEG unit of the Neurology department at the Pitié-Salpêtrière hospital
- Patients who have been informed and provided written informed consent to take part in the study
Who cannot take part
- Contraindication for an intracranial investigation (with macro-electrodes) : intercurrent infectious syndrome, decompensated associated pathology (cardiac, pulmonary, renal, hepatic), patient with increased risk of infection (ex: under immunosuppressive therapy)
- Pregnant or parturient woman
- Breastfeeding woman
- Minor person or legally protected adult (tutelage, legal guardianship, maintenance of justice)
Where in France
- Hôpital de la SalpêtrièreParis, FranceContact: Vincent Navarro, PrTaking people
About the trial
What the trial wants to find out
The main goal of this project is to study the mechanisms of epileptic activities using intracranial macro and micro electrodes in epileptic patients undergoing pre-surgical investigation.
Read full original descriptionShow less
The recordings will also be used to study physiological mechanisms like sleep and different cognitive functions.
The group in the trial
- Macro-microelectrode implantationTreatment being tested
Implantation of macro-micro electrodes of the Adtech Benkhe-Fried type in epileptic patients who are undergoing evaluation with intracranial EEG electrodes
Treatment: Intracranial macro-microelectrode recording
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Multi-level Approach of Brain Activity Using Intracranial Electrodes in Epileptic Patients
- Plain-language title
- Studies brain activity in epilepsy using implanted intracranial electrodesGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 28 September 2026