MOON Onsite MRI 10 Years After ACL Reconstruction
Key facts
- Who runs it
- The Cleveland Clinic
- Where
- Cleveland, United StatesSee the site
- Trial code
- Status
- Enrolling by invitation
- People taking part
- 219 people, planned
- Started
- 1 Jan 2020
- Expected to end
- 1 Jan 2030
- Type of study
- Observational, 2 groups
- Treatments tested
- No Intervention - Observational study with MRI
- Record updated
- 24 August 2026
Who can take part
- Age
- 22 years to 45 years
- Sex
- Women and men
- Healthy volunteers
- Can take part
The registry criteria, word for word
Show all 8 criteriaShow less
Who can take part
- Enrolled in MOON Onsite Study
- 12-33 years old at baseline (22-45 years for this study)
- ACL tear during a sport; no previous knee injury
- No graft rupture during follow-up
- No history of surgery on the contralateral knee
- No MRI contraindications
Who cannot take part
- History of surgery on contralateral knee
- Afraid of enclosed spaces
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 22 and 45 years old?
Where in United States
- Cleveland ClinicCleveland, United StatesNo longer taking part
About the trial
What the trial wants to find out
In this study, a total of 219 subjects from the MOON nested cohort will be studied at CCF, Vanderbilt and OSU, Table 1. Among them, some will have added MRI during their 10-year visit for the MOON study. Some subjects who finished their 10-year visit for the MOON Onsite study already will be called back to have MRI. PROMs and other information of these subjects will be collected through the MOON study.
The 2 groups in the trial
- Patients
Patients who had ACL reconstruction
Treatment: No Intervention - Observational study with MRI
- Controls
Controls who have no previous knee injury or surgery, no diagnosis of osteoarthritis
Treatment: No Intervention - Observational study with MRI
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Imaging Post-traumatic Osteoarthritis 10-years After ACL Reconstruction
- Fit questions
- Built from NCT04660955, who can take part
- Record updated
- 24 August 2026