Studying Fluid Intake and Weight Gain Between Kidney Dialysis Sessions
Observes how fluid intake and weight gain change between dialysis sessions in adults.
Plain-language title generated from the registry record
Registry title: Fluid Intake After Hemodialysis
Key facts
- Where
- London, CanadaSee the 2 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who have hemodialysis three times a week and do not have diabetes. It studies fluid intake and weight gain between dialysis sessions.
- Age
- 18 years or older
- Sex
- Women and men can join.
- Disease stage
- Chronic kidney disease treated with maintenance hemodialysis three times a week.
Main reasons for not taking part
- Diabetes mellitus
- Urine volume of more than 500 ml/day
- Able to measure own body weight and blood pressure
This trial only enrols participants on dialysis. The registry sentence this rests on: Thrice weekly maintenance hemodialysis
Read by machine on 12 November 2026.
Where in Canada
- Adam Linton UnitLondon, CanadaContact: Christopher W McIntyre, MD/PhDTaking people
- Westmount Kidney Care CentreLondon, CanadaContact: Christopher W. McIntyre, MD, PhDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
- Trial code
- NCT04721652
- Record updated
- 4 May 2026
- Original description
Interdialytic weight gain determines how much fluid (ultrafiltration) has to be removed during each hemodialysis session. High ultrafiltration volumes stress the organism and lead to a higher risk of death. Thirst is the main driving factor of interdialytic weight gain, and thirst is mainly driven by salt intake, molecules that increase blood tonicity (such as sugar in diabetics) and fluid loss (such as in dehydration and blood loss). It has been speculated that fluid loss during hemodialysis could increase the sense of thirst immediately following dialysis, but this statement requires further evidence.Read full original descriptionShow less
Fluid Intake After Hemodialysis: Investigating the Relationship Between Time and Weight Gain During the Interdialytic Interval
Interdialytic weight gain determines how much fluid (ultrafiltration) has to be removed during each hemodialysis session. High ultrafiltration volumes stress the organism and lead to a higher risk of death. Thirst is the main driving factor of interdialytic weight gain, and thirst is mainly driven by salt intake, molecules that increase blood tonicity (such as sugar in diabetics) and fluid loss (such as in dehydration and blood loss). It has been speculated that fluid loss during hemodialysis could increase the sense of thirst immediately following dialysis, but this statement requires further evidence.
Inclusion: Age ≥ 18 years; Thrice weekly maintenance hemodialysis; Willing and able to provide written informed consent.
Exclusion: Diabetes Mellitus; Residual Urinary Volume > 500 ml/day; Being able to self-monitor one's body weight and blood pressure.