Chronic kidney disease trials in Canada

In Canada 43 Also abroad 798

43 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
Where
Edmonton, Etobicoke, Halifax, Laval, London, Montreal, Oshawa, Québec, Saint John, Sarnia, Surrey, Toronto, Vancouver, Waterloo, Winnipeg
Age
18 years and over
People
5,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT06742723 · EU 2023-506460-14-00
Phase 3Taking people
A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)
Where
Brampton, Cambridge, Chicoutimi, Hamilton, Laval, Moncton, Montreal, Québec, Sarnia, Scarborough, Surrey, Trois-Rivières, Waterloo, Winchester, Windsor, Winnipeg
Age
50 years and over
People
7,140 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07241390 · EU 2025-523123-22-00
No phaseEnrolling by invitation
Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates 2.0
Where
Calgary, Edmonton, Hamilton, Montreal, Toronto, Vancouver
Age
0 Minutes to 2 weeks
People
8,000 worldwide
Run by
Indiana University
See details and how to joinNCT06823115
No phaseTaking people
Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)
Where
Toronto, Winnipeg
Age
21 years and over
People
125 worldwide
Run by
Bodyport Inc.
See details and how to joinNCT07059962
No phaseTaking people
Visceral Adipose Tissue and Liver Changes Associated With Semaglutide in CKD
Where
Edmonton
Age
18 years and over
People
52
Run by
University of Alberta
See details and how to joinNCT07187830
Phase 3Taking people
A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy
Where
Oshawa
Age
18 years to 100 years
People
540 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT04557462 · EU 2023-508690-92-00
Phase 4Not yet taking people in Canada
Patient-centred Intervention With Virtual Support for Obesity and Kidney Transplant Access
Where
London
Age
18 years and over
People
880
Run by
Kristin Clemens
See details and how to joinNCT07858331
No phaseTaking people
Telemonitoring of Hypertensive Patients With Chronic Kidney Disease
Where
Edmonton
Age
18 years and over
People
146
Run by
University of Alberta
See details and how to joinNCT04098354
Phase 3Taking people
A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria
Where
Calgary, Montreal
Age
1 year to 18 years
People
100 worldwide
Run by
Bayer
See details and how to joinNCT05457283 · EU 2023-504885-50-00
No phaseTaking people
DIALysis With EXpanded Solute Removal
Where
London, Orillia, Ottawa
Age
45 years and over
People
4,800
Run by
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
See details and how to joinNCT06660277
Phase 3Taking people
A Phase III Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With CKD Stage 3b and 4 (BalanceD-CKD)
Where
Brampton, Calgary, Edmonton, Greater Sudbury, Halifax, London, Mississauga, Montreal, Oakville, Québec, Toronto, Waterloo, Winnipeg
Age
18 years to 99 years
People
2,800 worldwide
Run by
AstraZeneca
See details and how to joinNCT07624305 · EU 2026-526114-90-00
Phase 2/3Taking people
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
Where
Edmonton, Halifax, Hamilton, Kingston, London, Longueuil, Montreal, Oshawa, Ottawa, Sherbrooke, Toronto, Vancouver, Winnipeg
Age
18 years and over
People
3,110 worldwide
Run by
CSL Behring
See details and how to joinNCT05485961 · EU 2022-500273-14-00
No phaseTaking people
CKD Specific Telemonitoring Platform to Minimize Adverse Outcomes in High Risk CKD Patients
Where
London, Scarborough Village, Winnipeg
Age
18 years and over
People
340
Run by
University of Manitoba
See details and how to joinNCT05726526
Phase 3Taking people
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
Where
Calgary, Edmonton, London, Montreal, Saint John, Scarborough Village, Sherbrooke, Toronto, Vancouver, Waterloo, Winnipeg
Age
18 years and over
People
7,000 worldwide
Run by
AstraZeneca
See details and how to joinNCT07753993 · EU 2025-523994-41-00
No phaseTaking people
Goal-Directed Therapy to Reduce Kidney and Cardiovascular Risk in Diabetic Kidney Disease (GOLD-STANDARD)
Where
Toronto
Age
18 years and over
People
100
Run by
Sunnybrook Health Sciences Centre
See details and how to joinNCT07434791
No phaseTaking people
Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease (PHOSPHATE)
Where
Calgary, Edmonton, Halifax, Kingston, London, Longueuil, Montreal, North York, Oakville, Orillia, Oshawa, Ottawa, Québec, Red Deer, Regina, Richmond Hill, Scarborough Village, Sherbrooke, Toronto, Vancouver, Winnipeg
Age
18 years and over
People
3,600 worldwide
Run by
The University of Queensland
See details and how to joinNCT03573089
No phaseNot yet taking people in Canada
Finerenone for AKI: a Multicenter, Randomized, Placebo-Controlled Feasibility Pilot Trial
Where
Montreal
Age
18 years and over
People
72
Run by
Jean-Maxime Côté
See details and how to joinNCT07775482
No phaseNot yet taking people in Canada
Liberalizing Potassium Restrictions in Patients Receiving Hemodialysis
Where
Toronto
Age
18 years and over
People
148
Run by
University of Ontario Institute of Technology
See details and how to joinNCT07772856
No phaseNot yet taking people in Canada
Designing and Implementing a Safety Net Surveillance Program for High Risk CKD
Where
Winnipeg
Age
18 years and over
People
972
Run by
University of Manitoba
See details and how to joinNCT07724288
No phaseNot yet taking people in Canada
Dialysis Less Frequently in the Elderly
Where
Halifax, Kingston, Montreal, Québec, St. John's, Vancouver
Age
70 years and over
People
210
Run by
Queen's University
See details and how to joinNCT07738731
Phase 4Taking people
Obesity Management for Kidney TRANSPLANTation: OK-TRANSPLANT 2
Where
London
Age
18 years and over
People
60
Run by
Western University, Canada
See details and how to joinNCT06396416
Phase 4Taking people
Glucagon-like-peptide-1 Receptor Agonists in Patients Receiving Maintenance Dialysis
Where
Toronto
Age
18 years and over
People
100
Run by
Unity Health Toronto
See details and how to joinNCT07017270
Phase 2Taking people
Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes
Where
Toronto
Age
18 years and over
People
60 worldwide
Run by
University of Washington
See details and how to joinNCT05822609
Phase 3Taking people
Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial
Where
London, Montreal
Age
18 years and over
People
100
Run by
Hamilton Health Sciences Corporation
See details and how to joinNCT06337838
No phaseTaking people
Feasibility and Pilot Testing of "My Heart and CKD" Online Shared Decision Aid
Where
Calgary, Edmonton
Age
18 years and over
People
220
Run by
University of Calgary
See details and how to joinNCT06920927