Checks bone and muscle weakness in older adults having hip fracture surgery
Tests checkups for weak bones and muscles in adults 65 and older with hip fracture.
Plain-language title generated from the registry record
Registry title: Study of Parameters of Osteosarcopenia in Patients With Hip Fracture
Key facts
- Where
- Bologna, ItalySee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people aged 65 or older who broke the neck of the thigh bone, possibly from weak bones, and will get a hip replacement. People having a hip replacement for osteoarthritis make up the comparison group.
- Age
- 65 years or older
- Sex
- All sexes can join.
- Disease stage
- Broken femoral neck (the neck of the thigh bone) that may be caused by osteoporosis, with little or no injury, to be treated with a hip replacement (endoprosthesis or hip arthroplasty).
- Earlier treatment
- People with a previous hip or other prosthetic surgery for bone or joint disease, or on long-term treatment with anti-osteoporotic drugs, immunosuppressive drugs or insulin, cannot join.
Main reasons for not taking part
- Earlier fractures caused by osteoporosis
- Earlier prosthetic surgery for orthopedic diseases
- Conditions that cause permanent inability to move
- Cancer, autoimmune diseases or severe muscle diseases
- Long-term viral infections (HBV, HCV, HIV)
Read by machine on 12 November 2026.
Where in Italy
- Istituto Ortopedico RizzoliBologna, ItalyContact: Nicola Baldini, M.D.Taking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Istituto Ortopedico Rizzoli
- Trial code
- NCT04730622
- Record updated
- 22 May 2026
- Original description
The study aims to assess the adequacy of a set of clinical and laboratory investigations for identifying the osteosarcopenia status in patients undergoing a hip replacement for a fragility fracture of the femoral neck. The control group will consist of patients undergoing a hip replacement for osteoarthritis, as the decrease in muscle function and bone quality is less severe in this condition than in osteoporosis.Read full original descriptionShow less
Study of Parameters of Bone Fragility and Sarcopenia in Patients Undergoing Surgery for Fracture of the Femoral Neck
The study aims to assess the adequacy of a set of clinical and laboratory investigations for identifying the osteosarcopenia status in patients undergoing a hip replacement for a fragility fracture of the femoral neck. The control group will consist of patients undergoing a hip replacement for osteoarthritis, as the decrease in muscle function and bone quality is less severe in this condition than in osteoporosis.
Inclusion: Patients who came to observation with femoral neck fracture of possible osteoporotic nature (no or minimal trauma) to be treated with endoprosthesis or hip arthroplasty; Competent patients who have signed consent to participate in the study (see Informed Consent section of this protocol).
Exclusion: Previous osteoporotic fractures; Previous prosthetic surgery for orthopedic diseases; Chronic treatment with anti-osteoporotic drugs, immunosuppressive drugs, and insulin; Pre-existing clinical conditions that led to permanent immobility; Neoplastic diseases; Autoimmune diseases; Chronic viral infections (HBV, HCV, HIV); Paget's disease; Severe myopathies.