Osteoarthritis trials in Italy

In Italy 49 Also abroad 827

49 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Analysis of the Loss of Muscle Force, Power and Motor Control to Predict the Risk of Falls in Patients With Knee OA
Where
Bologna
Age
65 years to 80 years
People
50
Run by
Istituto Ortopedico Rizzoli
See details and how to joinNCT06611618
No phaseTaking people
The Medacta International SMS Post-Marketing Surveillance Study
Where
Milan
Age
18 years to 75 years
People
550 worldwide
Run by
Medacta International SA
See details and how to joinNCT02748408
No phaseTaking people
MaioRegen Prime Study for the Treatment of Deep Osteochondral Lesion of the Knee
Where
Bologna
Age
18 years to 60 years
People
400 worldwide
Run by
Fin-Ceramica Faenza Spa
See details and how to joinNCT07332182
No phaseTaking people
Exactech Shoulder Post Market Clinical Follow-up Study
Where
Catania, Eboli
Age
21 years and over
People
20,000 worldwide
Run by
Exactech
See details and how to joinNCT05603728
Phase 3Taking people
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Where
Milan, Rome, San Donato Milanese, Udine, Verona
Age
18 years and over
People
400 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07509307 · EU 2024-520445-23-00
Phase 2Not yet taking people in Italy
Denosumab or Zoledronic acid for erosive hand osteoarthritis (EHOA) in patients with osteoporosis a randomized controlled trial (ZODIAC trial)
Where
Padova, Verona
Age
18 years and over
People
150
Run by
Azienda Ospedaliera Universitaria Integrata Verona
See details and how to join2026-526828-41-00
Phase 3Taking people
RANDOMISED, MULTICENTRE, DOUBLE-BLIND CLINICAL TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF MONTELUKAST VS. PLACEBO IN PATIENTS WITH EROSIVE/INFLAMMATORY OSTEOARTHRITIS OF THE HANDS. MOTHER Study.
Where
Florence, Rome, Turin, Velletri RM
Age
18 years and over
People
160 worldwide
Run by
Farmalider S.A.
See details and how to join2025-521802-17-00
Phase 3Taking people
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
Where
Milan, Modena, Naples, Rome, San Donato Milanese, Udine, Verona
Age
18 years and over
People
400 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07481630 · EU 2024-520444-42-00
No phaseTaking people
Analysis of the Pathophysiological and Functional State of the Knee Joint
Where
Bologna
Age
18 years to 60 years
People
25
Run by
Istituto Ortopedico Rizzoli
See details and how to joinNCT06490770
No phaseNot yet taking people in Italy
Intra-Articular Adelmidrol 2%/Hyaluronic Acid 1% With or Without m/umPEA, in Knee Pain Due to Joint Degeneration.
Where
Verona
Age
40 years and over
People
80
Run by
Universita di Verona
See details and how to joinNCT07680101
No phaseTaking people
Total Knee Arthroplasty: Fast Track Protocol is the Future?
Where
Bologna
Age
18 years to 78 years
People
64
Run by
Istituto Ortopedico Rizzoli
See details and how to joinNCT03869996
No phaseTaking people
Study of Parameters of Osteosarcopenia in Patients With Hip Fracture
Where
Bologna
Age
65 years and over
People
100
Run by
Istituto Ortopedico Rizzoli
See details and how to joinNCT04730622
No phaseTaking people
High-Energy Laser in the Conservative Treatment of Rhizarthrosis
Where
Bari
Age
18 years and over
People
42
Run by
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
See details and how to joinNCT07566507
No phaseTaking people
Outcomes of Surgical Treatment Using a Custom-made Device for Total Ankle and Talar Replacement in the Management of Severe Cases of Bone Loss or Bone Compromise: a Pilot Study.
Where
Bologna
Age
35 years to 75 years
People
26
Run by
Istituto Ortopedico Rizzoli
See details and how to joinNCT07569848
No phaseTaking people
Comparison of Custom and Standard Total Knee Replacements
Where
Bologna
Age
40 years to 70 years
People
20
Run by
Istituto Ortopedico Rizzoli
See details and how to joinNCT06122727
Phase 2/3Taking people
Adaptative, multicenter, randomized, double-blind, parallel-group, placebo controlled, clinical trial, on the efficacy and tolerability of different escalating doses of intra-articular clodronate in patients with painful knee osteoarthritis
Where
Alexandria, Andria, Brescia, Castel Goffredo, Castiglione delle Stiviere (MN), Florence, Genoa, Genova-Sampierdarena, Milan, Orbassano, Rome, Siena, Verona
Age
18 years and over
People
278
Run by
Spa Societa Prodotti Antibiotici S.p.A.
See details and how to joinNCT06263517 · EU 2024-511961-12-00
No phaseTaking people
"Transarterial Microembolization (TAME) in Inflammatory Knee Pathology"
Where
Bologna
Age
40 years and over
People
43
Run by
Istituto Ortopedico Rizzoli
See details and how to joinNCT07140367
No phaseTaking people
The Orienting Study
Where
Milan
Age
18 years and over
People
450
Run by
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
See details and how to joinNCT07504146
No phaseNot yet taking people in Italy
Surgeon Physiologic Stress During Unicompartmental Knee Arthroplasty: Manual vs Computer-Assisted Technique
Where
Forte dei Marmi
Age
18 years to 95 years
People
80
Run by
ASL Lecce
See details and how to joinNCT07495618
Phase 2Taking people
Implantation of Engineered Cartilage Grafts for Treatment of Patellofemoral Osteoarthritis Versus Surgical Comparators.
Where
Milan, Rome
Age
18 years to 70 years
People
150 worldwide
Run by
University Hospital, Basel, Switzerland
See details and how to joinNCT06576583 · EU 2024-513683-25-00
No phaseTaking people
An Artificial Intelligence-based Approach in Total Knee Arthroplasty: From Inflammatory Responses to Personalized Medicine
Where
Rome
Age
18 years and over
People
197
Run by
Fondazione Policlinico Universitario Campus Bio-Medico
See details and how to joinNCT06634654
No phaseTaking people
Long Term Evaluation of Clinical and Radiologic Results on Femoro-patellar Joint After High Tibial Osteotomy
Where
Bologna
Age
18 years to 65 years
People
50
Run by
Istituto Ortopedico Rizzoli
See details and how to joinNCT06251752
No phaseTaking people
Innovative Technologies for Salvage Procedures of Failed Treatments of Osteoarthritis: Biomimetics Solutions (CustomPN)
Where
Bologna
Age
18 years and over
People
15
Run by
Istituto Ortopedico Rizzoli
See details and how to joinNCT06527664
No phaseTaking people
Bone Marrow Versus Adipose Tissue as a Cell Source for Infiltrative Treatment of Knee Osteoarthritis
Where
Bologna
Age
40 years to 75 years
People
204
Run by
Istituto Ortopedico Rizzoli
See details and how to joinNCT06040957
No phaseNot yet taking people in Italy
Validation and Cultural Adaptation of the KOOS-ACL Scale for the Italian Population
Where
Milan
Age
18 years and over
People
120
Run by
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
See details and how to joinNCT07386405