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Studying Blood and Tissue Samples in People With Thyroid Nodules or Thyroid Cancer

Collects blood and tissue samples from adults with thyroid nodules or thyroid cancer.

Plain-language title generated from the registry record
Registry title: Development of Liquid Biopsy Technologies for Noninvasive Cancer Diagnostics in Patients With Suspicious Thyroid Nodules or Thyroid Cancer

Key facts

Where
Los Angeles, United StatesSee the site

Where in United States

  • UCLA / Jonsson Comprehensive Cancer CenterLos Angeles, United StatesTaking people

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Trial details

Who runs it
Jonsson Comprehensive Cancer Center
Trial code
NCT04742608
Record updated
10 March 2026
Original description
This study is being done to help researchers learn more about and successfully diagnose cancer using blood samples and tissue samples from surgeries in patients with suspicious thyroid nodules or thyroid cancer. Diagnosing cancer in this way, as opposed to biopsies, may be less invasive to the patient. Analyzing blood and tissues samples may also help researchers to differentiate non-cancerous tumors from thyroid cancer and detect high-risk mutations to guide treatment.Read full original descriptionShow less

Isolation and Characterization of Extracellular Vesicles in Patients With Thyroid Nodules and Thyroid Cancer

This study is being done to help researchers learn more about and successfully diagnose cancer using blood samples and tissue samples from surgeries in patients with suspicious thyroid nodules or thyroid cancer. Diagnosing cancer in this way, as opposed to biopsies, may be less invasive to the patient. Analyzing blood and tissues samples may also help researchers to differentiate non-cancerous tumors from thyroid cancer and detect high-risk mutations to guide treatment.

Inclusion: Aged 18 and older; Consented for thyroid surgery for thyroid cancer or indeterminate thyroid nodule.

Exclusion: Patients with concurrent malignancy.

ClinicalTrials.gov NCT04742608