How blood pressure medicines change heart and blood flow measures in early pregnancy

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for women in early pregnancy (before 15 weeks) who attend the Maternal Hypertension Center at Cabell Huntington Hospital. It studies how three blood pressure drugs affect the heart and blood flow.

Age

18 to 45 years old

Sex

Women only

Disease stage

Early pregnancy, before 15 weeks of gestation. The record lists high blood pressure and cardiac output problems as conditions.

Main reasons for not taking part

• Does not speak English
• Younger than 18 or older than 45 years
• Not willing or able to give consent
• Pregnancy longer than 15 weeks

This trial only enrols pregnant participants. The registry sentence this rests on: Gestational age prior to 15 weeks gestation

The registry criteria, word for word

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

• Are you between 18 and 45 years old?YesNo

What the trial wants to find out

The purpose of the research is to characterize the effect of labetalol, atenolol, and nifedipine on maternal hemodynamics early in pregnancy. Patients will be given medication based on their hemodynamics and asked to return for a repeat measurement.

The 2 groups in the trial

• Beta blockade

  Beta blocker (labetalol or atenolol) will be given for a cardiac output \>8 l/min.

  Treatment: Labetalol and Atenolol

• Nifedipine

  Nifedipine will be given for a mean arterial pressure \>100.