A Pilot Randomized Controlled Trial for Hand Osteoarthritis

Trial details

Who runs it

Baylor College of Medicine

Trial code

NCT04784065

Record updated

28 August 2025

Original description

This is a study involving people receiving care at the Michael E. DeBakey VA Medical Center, Houston Texas. We are studying people who have hand osteoarthritis (the most common form of arthritis that involves the hand) and testing treatments for the condition with the hope that we can help to improve hand pain as well as limit the damage that occurs related to the arthritis. People who choose to participate, are randomly assigned to one of two treatments, both expected to be helpful.Read full original descriptionShow less

This is a study involving people receiving care at the Michael E. DeBakey VA Medical Center, Houston Texas. We are studying people who have hand osteoarthritis (the most common form of arthritis that involves the hand) and testing treatments for the condition with the hope that we can help to improve hand pain as well as limit the damage that occurs related to the arthritis. People who choose to participate, are randomly assigned to one of two treatments, both expected to be helpful.

Inclusion: Enrolled to receive medical care at the Michael E. DeBakey VA Medical Center; At least 3 joints affected by distal interphalangeal (DIP) nodal hand OA; DIP nodal hand OA will be defined as Heberden's nodes on physical exam; Sufficiently severe frequent pain of at least one DIP; Frequent pain: pain on most days of the month for at least one month in the last year; Minimum VAS pain severity of 40 on a 0 - 100 scale.

Exclusion: Prior surgery on the DIP joints; Planned surgery for the DIP joints; History or current inflammatory arthritides (examples: gout, psoriatic arthritis, and rheumatoid arthritis); Pregnancy.

ClinicalTrials.gov NCT04784065