Qualitative Exploratory Study Among Reunionese Women and Their Partners Who Have a Child With Trisomy 21
Key facts
- Who runs it
- Centre Hospitalier Universitaire de la Réunion
- Where
- Réunion2 sites in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 28 people enrolled
- Started
- 28 Feb 2022
- Ended
- 30 Apr 2024
- Type of study
- Observational
- Treatments tested
- Interview
- Record updated
- 18 March 2026
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Can take part
The registry criteria, word for word
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Who can take part
- Parents:
- of a child born alive with Down Syndrome as of January 1, 2019 and registered within REMACOR
- living on the island of Reunion at the time of birth
- having a good understanding of French and/or Creole
- having given their written consent to the study
Who cannot take part
- Parents:
- with normal/negative prenatal screening (False positive)
- minors at the time of inclusion
- under guardianship or legal protection
- with a pathology preventing the interviews from taking place
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
According to data from French congenital malformation registries, the prevalence of Down Syndrome (DS) in 2017 (live births and medical termination of pregnancy (MToP)) in Reunion Island was the lowest in France (23.04 per 10,000 births), notably in relation to a young maternal age. However, if we look at live births, Reunion Island has the highest prevalence of DS in France (12.24 vs. 5.81 per 10,000 births), despite a well organized prenatal diagnosis (PND). In fact, the use of MToP in this context is the lowest in France (10.8 vs 26.3 per 10 000 births).
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Local specificities may have an impact on the choice of patients to undergo or not undergo a MToP in the context of PND of DS and explain why the rate of recourse to MToP is the lowest in France. To date, no qualitative study exploring the reasons why women and their partners do not undergo a MToP in the context of DS has been conducted in Reunion Island.
Thus, the main hypothesis is that the low recourse to MToP following PND of DS in Reunion Island could be explained by the beliefs, values or choices of Reunion Island women and their partners during pregnancy in relation to a specific family, socio-cultural and economic context.
Treatments tested
- Interview
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Record updated
- 18 March 2026