LIFT Intervention in Liver Transplant Candidates
Key facts
- Who runs it
- Northwestern University
- Where
- Chicago, United StatesSee the site
- Trial code
- Status
- Completed
- People taking part
- 81 people enrolled
- Started
- 1 Oct 2020
- Ended
- 1 Mar 2024
- Type of study
- Interventional
- Treatments tested
- "LIver FrailTy" intervention (LIFT)
- Record updated
- 15 May 2026
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- Patients with a diagnosis of liver cirrhosis being evaluated for liver transplantation in hepatology/transplant evaluation clinic
- English-speaking
- Patients with access to a smart phone (with videoconference capabilities)
- Vulnerable populations: We will include patients who are cognitively impaired due to hepatic encephalopathy and unable to consent for themselves
Who cannot take part
- Patients who require outpatient physical therapy
- Patients < 18 years of age
- Patients without the ability to consent for themselves or through a medical power of attorney
Where in United States
- Northwestern MedicineChicago, United StatesNo longer taking part
About the trial
What the trial wants to find out
Frailty is a significant problem in patients undergoing liver transplant and is associated with poor outcomes and survival. Hence, optimizing physical fitness and counteracting frailty is important. However, many interventions are very resource intensive and therefore not feasible.
Read full original descriptionShow less
In this study, the investigators aim to test the effectiveness of a newly designed intervention to improve frailty in liver transplant candidates. The "LIver FrailTy" intervention (LIFT) will consist of an evaluation by a physical therapist, an individualized home exercise prescription (HEP), exercise tracking using a smart phone application, daily text reminders to exercise and recurrent telephone check-ins.
The group in the trial
- LIFT subgroupTreatment being tested
Physical Therapy (PT) evaluation, an individualized home exercise prescription (HEP), daily text message reminders to exercise and weekly telephone check-ins with team members.
Treatment: "LIver FrailTy" intervention (LIFT)
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Home-based Physical Therapy Intervention to Decrease Frailty in Liver Transplant Candidates
- Record updated
- 15 May 2026