Studies teeth and gums in adults with Sjögren's syndrome
Looks at tooth wear and gum recession in adults with Sjögren's syndrome.
Plain-language title generated from the registry record
Registry title: Dental and Periodontal Status of Patients With Sjögren's Syndrome.
Key facts
- Where
- Ivry-sur-Seine, FranceSee the site
Where in France
- Service de Médecine bucco-dentaireIvry-sur-Seine, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Assistance Publique - Hôpitaux de Paris
- Trial code
- NCT04848870
- Record updated
- 30 December 2024
- Original description
Sjögren's syndrome (SS) is a rare chronic systemic autoimmune disease characterized by destruction of the exocrine glands, including the salivary glands.The lack of saliva exposes the patient to dental caries, and dental wear although this has rarely been shown in Sjögren's patients. Moreover, these patients seem to have more inflammation and gingival recession, although this has not been clearly identified in the literature.Read full original descriptionShow less
Prevalence and Characteristics of Dental and Periodontal Lesions in Patients With Sjögren's Syndrome. Establishment of a Biological Saliva Collection.
Sjögren's syndrome (SS) is a rare chronic systemic autoimmune disease characterized by destruction of the exocrine glands, including the salivary glands.The lack of saliva exposes the patient to dental caries, and dental wear although this has rarely been shown in Sjögren's patients. Moreover, these patients seem to have more inflammation and gingival recession, although this has not been clearly identified in the literature.
Our main objective is to assess the prevalence of dental wear and gingival recession in patients with Sjögren's syndrome by analyzing of the Basic Erosive Wear Examination (BEWE) score for erosions, Basic Erosive Wear Abrasion (BEWA) score for attrition and percentage of sites with periodontal recessions greater than 3 mm in relation to the total number of sites.
Our secondary objectives are to investigate a correlation between the prevalence of dental and gingival wear, gingival inflammation, Decayed, Missing, and Filled Teeth (DMFT) index and (1) salivary parameters and (2) oral quality of life.
The salivary samples will be kept in a biological collection within the URP2496 for later analysis (biological collection CB-SJO).
Inclusion: Patient with Sjögren Syndrome; Patient > 18 years old; Patient affiliated to a social security system, beneficiary or beneficiary of a right other than AME; Patient who speaks and understands French well enough to be able to read and understand the study information note; Patient who does not object to his participation in the study.
Exclusion: Patient having expressed his opposition to participate in the research.