Effect of Reparel Knee Sleeve With Knee Injection
Key facts
- Who runs it
- University of Alabama at Birmingham
- Where
- Birmingham, United StatesSee the site
- Trial code
- Status
- Completed
- People taking part
- 40 people enrolled
- Started
- 29 Jun 2022
- Ended
- 3 Dec 2025
- Type of study
- Interventional, 2 groupsOne group gets a placebo (a dummy treatment), for comparison.
- Treatments tested
- Reparel knee sleeve
- Corticosteroid injection
- Placebo knee sleeve
- Record updated
- 21 January 2026
Who can take part
- Age
- 18 years to 99 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- osteoarthritis visible on knee radiograph
- patient opting for non-surgical treatment
Who cannot take part
- prior surgery on the knee of interest
- malignancy in the knee of question
- bilateral symptomatic knee osteoarthritis
- hardware present on the knee of interest
- gross instability detected on physical exam
Where in United States
- UAB Hospital - HighlandsBirmingham, United StatesNo longer taking part
About the trial
What the trial wants to find out
The goals of treating knee osteoarthritis (OA) is to improve or maintain quality of life, mobility and function, pain relief, and improve inflammation. The different treatment options for knee OA have been extensively studied and implemented, but the optimum treatment is still undecided. There is a belief that anti-inflammatory sleeve technology may be beneficial in treating knee OA. The purpose of this study is to determine if the Reparel™ knee sleeve results in superior mobility, functionality, and pain outcomes as compared to a placebo knee sleeve in managing knee OA.
The 2 groups in the trial
- Reparel Sleeve GroupTreatment being tested
Reparel sleeve and corticosteroid injection
Treatment: Reparel knee sleeve and Corticosteroid injection
- Placebo Sleeve GroupPlacebo, for comparison
Placebo sleeve and corticosteroid injection
Treatment: Corticosteroid injection and Placebo knee sleeve
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Effects of Corticosteroid Injection Plus Reparel™ Knee Sleeve on Knee Osteoarthritis: A Randomized Clinical Trial
- Record updated
- 21 January 2026