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Speech Therapy Study for People With Progressive Language Loss

Tests semantic speech therapy in adults with mild to moderate progressive semantic aphasia.

Plain-language title generated from the registry record
Registry title: Semantic Rehabilitation for Patients With Primary Progressive Semantic Aphasia

Key facts

Where
Toulouse, FranceSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 100 years old?

Source: NCT04957537, who can take part

Where in France

  • CHU ToulouseToulouse, FranceTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
University Hospital, Toulouse
Trial code
NCT04957537
Record updated
11 August 2026
Original description
This project aims to measure the effect of a semantic rehabilitation protocol for patients with primary progressive semantic aphasia and using the SCED methodology.Read full original descriptionShow less

Evaluation of the Effect of a Semantic Rehabilitation in Patients in the Mild to Moderate Stage of Primary Progressive Semantic Aphasia : a SCED Study

This project aims to measure the effect of a semantic rehabilitation protocol for patients with primary progressive semantic aphasia and using the SCED methodology.

Inclusion: Have a diagnosis of primary progressive semantic aphasia according to the criteria of Gorno-Tempini et al (2011) (Appendix A); Being in the mild to moderate stage of dementia (MMSE score between 10 and 28) (Crum et al., 1993; Derouesné et al., 1999); Common French; Being affiliated to a social security scheme; Being over the age of 18 years old.

Exclusion: Chronical use of drugs and/or alcohol; Have significant uncorrected visual and/or hearing impairment; Have a history of brain injuries, major head trauma; Have untreated psychiatric disorders; Have significant motor and/or comprehension problems that make it impossible to take part in the study; Under guardians or curators; Severe depression (Beck's depression scale score > 9) (Beck \& al., 1961).

ClinicalTrials.gov NCT04957537