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Taking peoplePhase 1

Tests a CCR8 antibody alone and with PD-1 therapy in advanced solid tumors

Tests denikitug, alone or with anti-PD-1 therapy, in adults with advanced solid tumors.

Plain-language title generated from the registry record
Registry title: A Phase 1 Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Denikitug (GS-1811), an Afucosylated Anti-CCR8 Monoclonal Antibody, as Monotherapy and in Combination With an Anti–PD-1 Monoclonal Antibody in Adults With Advanced Solid Tumors

Key facts

Where
Edegem, Hasselt, and Leuven, BelgiumSee the 3 sites
Phase
Phase 1

Where in Belgium

  • Antwerp University HospitalEdegem, BelgiumNo longer taking part
  • JESSA ZiekenhuisHasselt, BelgiumNo longer taking part
  • UZ LeuvenLeuven, BelgiumNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Gilead Sciences Inc.
Trial code
NCT05007782EU 2022-501684-40-00
Record updated
21 September 2026