Exercise study of fitness and lungs in young people with childhood illness
Studies fitness and lung function in young people after leukemia, heart transplant, or lung disease.
Plain-language title generated from the registry record
Registry title: Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise
Key facts
- Where
- Minneapolis, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 8 and 25 years old?
Source: NCT05025774, who can take part
Where in United States
- Masonic Cancer CenterMinneapolis, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Masonic Cancer Center, University of Minnesota
- Trial code
- NCT05025774
- Record updated
- 24 November 2025
- Original description
This study aims to more accurately assess cardiac function, ventilation and exercise capacity in a non-invasive fashion, and to better characterize exercise intolerance in the setting of three populations of individuals with chronic diseases of childhood (acute lymphoblastic leukemia (ALL), chronic lung disease (CLD) of prematurity, and post-heart transplant (HT))Read full original descriptionShow less
Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant Bronchopulmonary Dysplasia (BPD, Also Known as Chronic Lung Disease of Prematurity) Through Exercise (FLASHLITE)
This study aims to more accurately assess cardiac function, ventilation and exercise capacity in a non-invasive fashion, and to better characterize exercise intolerance in the setting of three populations of individuals with chronic diseases of childhood (acute lymphoblastic leukemia (ALL), chronic lung disease (CLD) of prematurity, and post-heart transplant (HT))
Inclusion: Cases:; Acute lymphoblastic leukemia survivor, OR living with chronic lung disease of prematurity, OR living with heart transplant; 8-25 years old; Height: ≥ 48 inches; Ambulatory without assistance; English speaking; Normotensive (<95th percentile for age; okay if managed with antihypertensive medication); SpO2 >92%; Not pregnant; ALL survivor specific: must have completed therapy ≥ 3 months prior to study entry; Controls; 8-25 years old; Height: ≥ 48 inches; Ambulatory without assistance; English speaking; No history of arrhythmia or known cardiac dysfunction at baseline; Normotensive (<95th percentile for age; okay if managed with antihypertensive medication); SpO2 >95%; Not pregnant.
Exclusion: Cases:; ALL specific: received cranial radiation, bone marrow transplant recipients; Investigator or patient's primary physician deems the patient unsuitable for the study; Controls:; History of malignancy, CLD or HT or any other diagnosis which may reduce cardiorespiratory function; Investigator deems the patient unsuitable for the study.