Collects blood and spinal fluid samples to study amyotrophic lateral sclerosis
Collects blood and spinal fluid samples from adults with ALS for future research.
Plain-language title generated from the registry record
Registry title: Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders
Key facts
- Where
- Jacksonville, United StatesSee the site
Where in United States
- Mayo Clinic in FloridaJacksonville, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mayo Clinic
- Trial code
- NCT05116943
- Record updated
- 16 December 2025
- Original description
The purpose of this study is to collect CSF and blood samples that can be used in future research studies to identify potential biomarkers in blood and cerebrospinal fluid (CSF) collected in Amyotrophic Lateral Sclerosis (ALS) patients.Read full original descriptionShow less
Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders
The purpose of this study is to collect CSF and blood samples that can be used in future research studies to identify potential biomarkers in blood and cerebrospinal fluid (CSF) collected in Amyotrophic Lateral Sclerosis (ALS) patients.
Inclusion: Clinical diagnosis of possible, laboratory-supported probable, probable or definite ALS according to modified eL Escorial criteria, suspected ALS according to original el Escorial criteria, or diagnosis of a similar neurodegenerative disorder; Willing to provide consent, or assent, if physically unable to consent owing to disease-related muscle weakness; No personal history of ALS, ALS-FTD or other motor neuron disease; Subjects with family history of ALS, ALS-FTD the affected family member needs to be a first, second, or third degree blood relative; Willing to provide consent.
Exclusion: History of medical disorder that leaves in question whether neurological signs and symptoms potentially related to a neurodegenerative disease may be caused by another unrelated disorder; For lumbar puncture, an increased risk of bleeding complications or allergy to local anesthetic administered or skin antiseptic used for lumbar puncture; For lumbar puncture, an increased risk of bleeding complications or allergy to local anesthetic administered or skin antiseptic used for lumbar puncture; Limited mental capacity rendering the subject unable to comply with lumbar puncture or standard phlebotomy procedures; Limited mental capacity rendering the subject unable to comply with lumbar puncture or standard phlebotomy procedures.