Testing sleep-study guided breathing support in motor neurone disease
Tests a sleep study used to adjust breathing machines in adults with motor neurone disease.
Plain-language title generated from the registry record
Registry title: Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease
Key facts
- Where
- Adelaide, Brisbane, Canberra, Melbourne, Perth, and Sydney, AustraliaSee the 13 sites
Where in Australia
- Flinders Medical CentreAdelaide, AustraliaNot yet recruiting
- The Prince Charles HospitalBrisbane, AustraliaNot yet recruiting
- Motor Neurone Disease AustraliaCanberra, AustraliaNot yet recruiting
- Austin HealthMelbourne, AustraliaTaking people
- Australian MND RegistryMelbourne, AustraliaNot yet recruiting
- FightMNDMelbourne, AustraliaNot yet recruiting
- Institute for Breathing and SleepMelbourne, AustraliaNot yet recruiting
- Monash UniversityMelbourne, AustraliaNot yet recruiting
- University of MelbourneMelbourne, AustraliaNot yet recruiting
- Sir Charles Gairdner HospitalPerth, AustraliaNot yet recruiting
- Macquarie UniversitySydney, AustraliaNot yet recruiting
- Royal Prince Alfred HospitalSydney, AustraliaNot yet recruiting
- Westmead HospitalSydney, AustraliaNot yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Melbourne
- Trial code
- NCT05136222
- Record updated
- 23 June 2022
- Original description
A two-arm, individual participant randomised controlled, assessor-blinded trial in 7 MND care centres across Australia will be undertaken.Read full original descriptionShow less
A Multi-centre Randomised Controlled Trial of Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease (PSG4NIVinMND; 3, Three Letter Acronyms [3TLA])
A two-arm, individual participant randomised controlled, assessor-blinded trial in 7 MND care centres across Australia will be undertaken.
Inclusion: Age >18 years; Clinical indication to commence long term NIV; Confirmed clinical diagnosis of underlying condition.
Exclusion: Hypoventilation attributable to medications with sedative/respiratory depressant side- effects; Use of NIV for more than 1 month in the previous 3 months; Previous intolerance of NIV; Medically unstable; Inability to provide informed consent.