ALS (motor neurone disease) trials in Australia

In Australia 7 Also abroad 225

7 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 2/3Taking people
Trial on the Biological and Clinical Effects of Acetyl-L-carnitine in ALS
Where
Sydney
Age
18 years and over
People
246 worldwide
Run by
Mario Negri Institute for Pharmacological Research
See details and how to joinNCT06126315 · EU 2023-509853-29-00
Phase 1/2Taking people
A Clinical Trial to Evaluate NB-4746 in Participants With Amyotrophic Lateral Sclerosis.
Where
Bedford Park, Brisbane, Caulfield South, Concord, Nedlands, Randwick
Age
18 years to 80 years
People
80 worldwide
Run by
Nura Bio
See details and how to joinNCT07369076
Phase 1/2Taking people
First in Human (FIH) Study of ALN-SOD in Adult Participants With Amyotrophic Lateral Sclerosis Associated With Mutation in the SOD1 Gene (SOD1-ALS)
Where
Birtinya, Concord, Sydney
Age
18 years and over
People
54 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT06351592 · EU 2023-510344-20-00
Phase 2Taking people
Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis
Where
Caulfield South, Southport, Sydney
Age
18 years and over
People
240 worldwide
Run by
Zydus Therapeutics Inc.
See details and how to joinNCT07023835 · EU 2025-522580-15-00
Phase 1Taking people
Safety and Tolerability Study of CTx1000 In Participants With Amyotrophic Lateral Sclerosis
Where
Sydney
Age
18 years to 80 years
People
15
Run by
Celosia Therapeutics Pty Ltd
See details and how to joinNCT07401121
Phase 1Not yet taking people in Australia
Safety of Intrathecal Riluzole in Patients With Amyotrophic Lateral Sclerosis
Where
Bedford Park, Birtinya
Age
18 years and over
People
10
Run by
Brain Trust Bio
See details and how to joinNCT07093268
No phaseTaking people
Polysomnographic Titration of Non-invasive Ventilation in Motor Neurone Disease
Where
Adelaide, Brisbane, Canberra, Melbourne, Perth, Sydney
Age
18 years and over
People
244
Run by
University of Melbourne
See details and how to joinNCT05136222