Compares two bowel cleansing methods before rectal surgery in adults with rectal growths
Compares Fleet enemas with Pico-Salax tablets to clean the bowel before surgery.
Plain-language title generated from the registry record
Registry title: TES RCT Fleet Enema vs Oral Mechanical Bowel Prep
Key facts
- Where
- Halifax, CanadaSee the site
- Phase
- Phase 4
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT05148494, who can take part
Where in Canada
- Victoria General HospitalHalifax, CanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Nova Scotia Health Authority
- Trial code
- NCT05148494
- Record updated
- 21 August 2026
- Original description
There is no consensus about the best bowel preparation prior to transanal endoscopic surgery TES). Cleanliness and visibility in the rectosigmoid and rectum are of utmost importance, possibly even more so than during colonoscopy, to facilitate safe, precise and efficient resection of the rectal lesion and potentially adequate closure of the defect. Both Fleet enemas and oral mechanical bowel preparation are considered standard of care in preparation for TES. This single center two arm single blinded randomized controlled trial will compare the effectiveness of Fleet enemas in comparison to Pico Salax oral mechanical bowel preparation in cleansing the rectum as measured by a modified version of the Ottawa Bowel Prep Scale.Read full original descriptionShow less
Transanal Endoscopic Surgery: a Randomized Controlled Trial Comparing Fleet Enema vs Oral Mechanical Bowel Prep (TESEO Trial)
There is no consensus about the best bowel preparation prior to transanal endoscopic surgery TES). Cleanliness and visibility in the rectosigmoid and rectum are of utmost importance, possibly even more so than during colonoscopy, to facilitate safe, precise and efficient resection of the rectal lesion and potentially adequate closure of the defect. Both Fleet enemas and oral mechanical bowel preparation are considered standard of care in preparation for TES. This single center two arm single blinded randomized controlled trial will compare the effectiveness of Fleet enemas in comparison to Pico Salax oral mechanical bowel preparation in cleansing the rectum as measured by a modified version of the Ottawa Bowel Prep Scale.
Inclusion: undergoing transanal endoscopic surgery at the QEII Health Sciences Center in Halifax by one of the colorectal trained surgeons.
Exclusion: previous pelvic radiation; repeat transanal surgery for the same lesion; chronic steroid use; Transanal Endoscopic Surgery combined with another surgical procedure; inflammatory bowel disease; clear diagnosis of congestive heart failure; age over 75; chronic constipation not well controlled with diet or stool softening agents; patient unable to self-administer enemas; patient unable to tolerate either of the 2 bowel preps due to medical reasons; daily use of Lasix or similar loop diuretic.