Compares two bowel cleansing methods before rectal surgery in adults with rectal growths
Compares Fleet enemas with Pico-Salax tablets to clean the bowel before surgery.
Plain-language title generated from the registry record
Registry title: TES RCT Fleet Enema vs Oral Mechanical Bowel Prep
Key facts
- Where
- Halifax, CanadaSee the site
- Phase
- Phase 4
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults having transanal endoscopic surgery for a rectal lesion at one hospital in Halifax. It compares two ways of cleaning the bowel before surgery: Fleet enemas and Pico Salax drink.
- Age
- 18 Years to 75 Years
- Sex
- All sexes can join.
- Disease stage
- People having transanal endoscopic surgery with one of the colorectal trained surgeons at the QEII Health Sciences Center in Halifax.
- Earlier treatment
- No previous pelvic radiation. No earlier transanal surgery for the same lesion.
Main reasons for not taking part
- Chronic constipation not well controlled with diet or stool softeners
- Inflammatory bowel disease
- Clear diagnosis of congestive heart failure
- Daily use of Lasix or a similar loop diuretic, or chronic steroid use
- Transanal endoscopic surgery combined with another surgical procedure
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Source: NCT05148494, who can take part
Where in Canada
- Victoria General HospitalHalifax, CanadaContact: Katerina NeumannTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Nova Scotia Health Authority
- Trial code
- NCT05148494
- Record updated
- 21 August 2026
- Original description
There is no consensus about the best bowel preparation prior to transanal endoscopic surgery TES). Cleanliness and visibility in the rectosigmoid and rectum are of utmost importance, possibly even more so than during colonoscopy, to facilitate safe, precise and efficient resection of the rectal lesion and potentially adequate closure of the defect. Both Fleet enemas and oral mechanical bowel preparation are considered standard of care in preparation for TES. This single center two arm single blinded randomized controlled trial will compare the effectiveness of Fleet enemas in comparison to Pico Salax oral mechanical bowel preparation in cleansing the rectum as measured by a modified version of the Ottawa Bowel Prep Scale.Read full original descriptionShow less
Transanal Endoscopic Surgery: a Randomized Controlled Trial Comparing Fleet Enema vs Oral Mechanical Bowel Prep (TESEO Trial)
There is no consensus about the best bowel preparation prior to transanal endoscopic surgery TES). Cleanliness and visibility in the rectosigmoid and rectum are of utmost importance, possibly even more so than during colonoscopy, to facilitate safe, precise and efficient resection of the rectal lesion and potentially adequate closure of the defect. Both Fleet enemas and oral mechanical bowel preparation are considered standard of care in preparation for TES. This single center two arm single blinded randomized controlled trial will compare the effectiveness of Fleet enemas in comparison to Pico Salax oral mechanical bowel preparation in cleansing the rectum as measured by a modified version of the Ottawa Bowel Prep Scale.
Inclusion: undergoing transanal endoscopic surgery at the QEII Health Sciences Center in Halifax by one of the colorectal trained surgeons.
Exclusion: previous pelvic radiation; repeat transanal surgery for the same lesion; chronic steroid use; Transanal Endoscopic Surgery combined with another surgical procedure; inflammatory bowel disease; clear diagnosis of congestive heart failure; age over 75; chronic constipation not well controlled with diet or stool softening agents; patient unable to self-administer enemas; patient unable to tolerate either of the 2 bowel preps due to medical reasons; daily use of Lasix or similar loop diuretic.