Speed of Processing (SoP) Training Plus α-tACS
Key facts
- Who runs it
- Portucalense University
- Where
- Portugal1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Terminated
- People taking part
- 40 people enrolled
- Started
- 19 Apr 2022
- Ended
- 5 Sept 2025
- Type of study
- Interventional, 3 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- alpha tACS
- Speed of Processing Training
- Record updated
- 12 September 2025
- Why it stopped
- The study was halted due to the COVID19, and then due to the lack of funding to continue the study
Who can take part
- Age
- 65 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 5 criteriaShow less
Who can take part
- Community-dwelling adults aged 65 years and older, with cognitive complains in memory or other functions, which have declined over time
Who cannot take part
- Diagnosis of Alzheimer´s Disease, any other medical condition that may predispose participants for a forthcoming decline in function, or that may increase their risk of mortality during the duration of the study
- Score in the mini mental examination less than 23 (or over 28)
- Any contra-indication to tACS, severe sensory losses or communication difficulties that will prevent them from successfully complete the training
- Had any cognitive training in the past
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The current proposal aims to assess if the combination of Speed of Processing (SoP) training with alpha tACS (α-tACS) is able to increase brain speed of processing as assessed by the Useful Field of View (UFOV) when comparing to SoP training plus sham α-tACS. Moreover, a second aim is to assess if those changes in speed of processing transfer to other cognitive domains, such as memory, language and executive functioning. Furthermore, the mechanisms underlying these interventions will be tested, namely to assess brain connectivity and coherence as assessed by EEG. To that purpose, the aim of the current proposal is to conduct a double-blind, parallel randomized trial assessing the effects of combining SoP with alpha endogenous tACS (either active or sham) in participants with Mild Cognitive impairment (MCI).
The 3 groups in the trial
- Active tACS plus active SoPExisting treatment, for comparison
Active alpha range tACS plus Speed of Processing Training
Treatment: alpha tACS and Speed of Processing Training
- Active tACS plus sham SoPExisting treatment, for comparison
Active alpha range tACS plus sham Speed of Processing Training
Treatment: alpha tACS
- Sham tACS plus active SoPExisting treatment, for comparison
Sham alpha range tACS plus Speed of Processing Training
Treatment: Speed of Processing Training
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Speed of Processing (SoP) Training Plus α-tACS in People With Mild Cognitive Impairment: a Double Blind, Parallel, Placebo Controlled Trial Study Protocol
- Record updated
- 12 September 2025