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Mild cognitive impairment

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Where research stands todayUpdated 15 Nov 2026
Trial-stage treatments you can join–open now
in United States
Studies published in the last 12 months00 in people · 0 in animals · 0 in the lab
Support organisations2organisations
in United States1 helpline
Offer tissue or dataGive a sample or your health data to research.Approved treatmentsMedicines approved for mild cognitive impairment around the world.“Miracle cure” fact checkerSaw a cure online? Check it before you pay.

Trial-stage treatments and research studies you can join

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Get notified of new trialsUnited States, all cities, all phases
Your ageShows only trials that take people your age.
Phase
  1. Trial-stage treatmentTaking people
    Clinical trial: Active tDCS and Cognitive Training Intervention
    Minneapolis, United StatesAlso San DiegoAge 18 to 60
  2. Trial-stage treatmentTaking people
    Brain stimulation plus talk therapy for insomnia in mild cognitive impairment

    Tests magnetic brain stimulation with sleep therapy in people with mild cognitive impairment and insomnia.

    Boston, United StatesAge 60+
  3. Trial-stage treatmentPhase 2Taking people
    Donanemab for early memory and thinking decline with Lewy body features

    Tests donanemab against placebo in people with early cognitive decline and Lewy body features.

    Atlantis, United StatesAlso Aventura, Beaumont, Bolivar, Carlsbad, Chandler, Charlestown, Dallas, Delray Beach, …Age 55 to 85
  4. Trial-stage treatmentPhase 1Taking people
    Tests LY3954068 safety in people with early Alzheimer's disease

    Tests LY3954068 injected into the spinal fluid in people with early Alzheimer's disease.

    Charlestown, United StatesAlso Decatur, Durham, Maitland, The Villages, Toms RiverAge 50 to 85
  5. Trial-stage treatmentTaking people
    Testing a sleep headband and exercise in adults with memory problems or Alzheimer's

    Tests a sleep headband and an exercise routine in adults aged 55 to 80.

    Miami, United StatesAge 55 to 80
  6. Trial-stage treatmentPhase 2Taking people
    Tests tau-directed treatments, alone or with donanemab, in people with early Alzheimer's

    Tests tau-directed drugs, alone or with donanemab, in adults aged 50-80 with early Alzheimer's.

    Boston, United StatesAlso Lexington, Nashville, Phoenix, Providence, San Francisco, SeattleAge 50 to 80
  7. Trial-stage treatmentPhase 2Soon in United States
    Phase 2 trial: Tadalafil 5 mg
    Santa Monica, United StatesAge 60 to 90
  8. Trial-stage treatmentTaking people
    Brain stimulation for mild memory and thinking problems in Parkinson's disease

    Tests magnetic brain stimulation for mild thinking problems in people with Parkinson's disease.

    Charleston, United StatesAge 50 to 85
  9. Trial-stage treatmentTaking people
    Tests light treatment for memory problems from Alzheimer's disease

    Tests forehead light treatment in adults with memory problems from Alzheimer's disease.

    Los Angeles, United StatesAge 55 to 89
  10. Trial-stage treatmentPhase 2Taking people
    NPC1, a parthenolide and ipriflavone combination, in people with Alzheimer's disease or memory decline

    Tests NPC1 in adults with Alzheimer's disease or early memory and thinking problems.

    Boston, United StatesAge 55+
  11. Trial-stage treatmentSoon in United States
    Clinical trial: Active tES
    Baltimore, United StatesAge 45 to 85
  12. Trial-stage treatmentTaking people
    Magnetic brain stimulation for memory problems in early Alzheimer's disease

    Tests magnetic stimulation of the cerebellum for short-term memory in early Alzheimer's disease.

    Houston, United StatesAge 55 to 90
  13. Trial-stage treatmentPhase 2Soon in United States
    Insulin or Empagliflozin Added to Anti-Amyloid Treatment in Early Alzheimer's Disease

    Tests intranasal insulin or empagliflozin in early Alzheimer's disease treated with anti-amyloid therapy.

    Winston-Salem, United StatesAge 55 to 85
  14. Trial-stage treatmentPhase 1/2Soon in United States
    Testing 2-HOBA in people with early Alzheimer's disease or mild memory decline

    Tests 2-HOBA against placebo in adults with early Alzheimer's or mild cognitive impairment.

    Nashville, United StatesAge 55 to 85
  15. Trial-stage treatmentSoon in United States
    Insole and Ankle Device for Monitoring Memory Decline Over Time

    Tests a worn insole and ankle device that tracks walking in people with memory problems.

    Saint Paul, United StatesAge 55+
  16. Trial-stage treatmentPhase 1/2Taking people
    Phase 1/2 trial: Pecan snack, Pretzel snack
    Lubbock, United StatesAge 50+
  17. Trial-stage treatmentPhase 1Taking people
    Tests psilocybin for depression in people with memory decline

    Tests psilocybin for depression in adults with mild cognitive impairment or early Alzheimer's.

    Baltimore, United StatesAge 18 to 85
  18. Trial-stage treatmentTaking people
    Testing Over-the-Counter Hearing Aids for Hearing Loss and Memory Problems

    Compares over-the-counter hearing aids with communication tips in older adults with hearing and memory loss.

    Evanston, United StatesAlso La Crosse, MadisonAge 60 to 90
  19. Trial-stage treatmentTaking people
    Brain Stimulation Guided by Brain Signals for Memory and Thinking Decline

    Tests magnetic brain stimulation timed by brain signals in older adults with memory problems.

    Austin, United StatesAge 18 to 90
  20. Trial-stage treatmentTaking people
    Clinical trial: Virtual Reality (VR) sessions
    Houston, United StatesAge 55 to 90

Support organisations

Patient organisations and helplines in United States, for you and your family.

We have no organisations for this disease listed in United States yet. General support there is below.

General support in United States

  • 988 Suicide & Crisis Lifeline

    US national 24/7 free and confidential lifeline for anyone in suicidal crisis or emotional distress, reachable by calling or texting 988 or by chat.

    988lifeline.org
  • MedlinePlus

    Free, easy-to-read health information service of the US National Library of Medicine (NIH) on diseases, conditions, drugs and wellness.

    medlineplus.gov

International organisations

Patient organisation umbrella bodies

Offer tissue or data

There are three ways to help research move faster.

Give tissue or bloodA biobank stores your sample so many research teams can use it.No open programme yet
Share your health dataA patient registry collects your health data, without your name, for research.How to join
Take part as a healthy volunteerStudies also need people without the disease, for comparison. Family and friends can help.Volunteer

“Miracle cure” fact checker

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  1. Is there a published study in people?
  2. Can I have the full price in writing?
  3. What does my doctor say?

“Cures” others already fact-checked

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