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Taking people in GermanyNo phase

Testing two catheter ablation approaches for recurring atrial tachycardia after prior heart procedures

Compares standard and minimal catheter ablation for atrial tachycardia in adults after prior heart procedures.

Plain-language title generated from the registry record
Registry title: Ablation of Consecutive Atrial Tachycardia

Key facts

Where
Berlin, Düsseldorf, Hagen, Hamburg, Karlsruhe, and Kiel, GermanySee the 6 sites

Where in Germany

  • Vivantes Klinikum am Urban BerlinBerlin, GermanyTaking people
  • Evangelic Hospital DüsseldorfDüsseldorf, GermanyTaking people
  • Evangelic Hospital Hagen-HaspeHagen, GermanyTaking people
  • Asklepios St. GeorgHamburg, GermanyTaking people
  • Städtisches Klinikum KarlsruheKarlsruhe, GermanyTaking people
  • Universitatsklinikum Schleswig-HolsteinKiel, GermanyTaking people

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Trial details

Who runs it
Evangelical Hospital Düsseldorf
Trial code
NCT05239364
Record updated
30 April 2026
Original description
Ablation of consecutive atrial tachycardia (AT) after ablation of atrial fibrillation (AF) or cardiac surgery can be challenging due to complex substrate and AT mechanisms. A substantial portion of patients is known to show various tachycardias and recurrences occur in a noticeable number of cases. With the availability of novel ultra-high-density mapping techniques characterization and understanding of AT mechanisms and underlying substrate can be improved. Aim of this prospective, multi-center, randomized study is to compare a standard AT ablation approach versus minimalized ablation of the clinical AT in regards to arrhythmia free survival.Read full original descriptionShow less

Ablation of CONseCutive atriaL Tachycardia gUided by Ultra-high-DEnsity Mapping

Ablation of consecutive atrial tachycardia (AT) after ablation of atrial fibrillation (AF) or cardiac surgery can be challenging due to complex substrate and AT mechanisms. A substantial portion of patients is known to show various tachycardias and recurrences occur in a noticeable number of cases. With the availability of novel ultra-high-density mapping techniques characterization and understanding of AT mechanisms and underlying substrate can be improved. Aim of this prospective, multi-center, randomized study is to compare a standard AT ablation approach versus minimalized ablation of the clinical AT in regards to arrhythmia free survival.

Inclusion: Consecutive AT subsequent to prior AF ablation procedure or cardiac surgery; Surface ECG-documentation of AT as primary clinical arrhythmia; ECG indicating stable, map-able AT (stable activation sequence, and CL stability) with cycle length ≥ 200ms.

Exclusion: No previous atrial fibrillation ablation procedure or cardiac surgery; Pregnant women or women of childbearing potential without a negative pregnancy test within 48 hours prior to treatment; History of hemorrhagic diathesis or other coagulopathies; Has any condition that would make participation not be in the best interest of the subject; < 18 years; Contraindications for oral anticoagulation; Hyper- or hypothyroidism.

ClinicalTrials.gov NCT05239364