Atrial fibrillation trials in Germany

In Germany 61 Also abroad 724

61 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable
Where
Berlin, Dresden, Halle (saale), Tuebingen, Wermsdorf
Age
18 years and over
People
2,628 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07430956 · EU 2025-521618-25-00
No phaseTaking people
AI-Based Tools for Stroke Diagnosis, Treatment and Outcome Prediction: a Multicentre Prospective Observational Study
Where
Hamburg
Age
18 years and over
People
10,000 worldwide
Run by
Hospital Universitari Vall d'Hebron Research Institute
See details and how to joinNCT07924371
No phaseTaking people
Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation Therapy
Where
Berlin, Bonn, Göttingen, Hamburg, Heidelberg, Leipzig, Lübeck, Mannheim, Tübingen
Age
18 years and over
People
482 worldwide
Run by
Insel Gruppe AG, University Hospital Bern
See details and how to joinNCT05976685
Phase 3Taking people
Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation
Where
Altenburg, Bonn, Dresden, Essen, Hagen, Halle (saale), Kaiserslautern, Minden, Tuebingen, Wermsdorf
Age
18 years and over
People
15,364 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07626411 · EU 2025-521617-97-00
No phaseTaking people
Structured Treatment and Resource Efficiency Assessment With Lean Six Sigma Integration for Pulmonary Vein Isolation
Where
Wiesbaden
Age
18 years and over
People
94
Run by
St. Josefs-Hospital Wiesbaden GmbH
See details and how to joinNCT07910370
Phase 2Taking people
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
Where
Bad Homburg, Berlin, Hamburg
Age
18 years and over
People
165 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07217067
No phaseTaking people
Comprehensive LEFt Atrial Appendage Occlusion With Rhythm Restoration
Where
Berlin, Frankfurt am Main, Lübeck
Age
18 years and over
People
240 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT07523620
No phaseTaking people
Reliability of Multiple-Repetition-Maximum Tests in Patients With Cardiovascular Disease or Risk Factors
Where
München
Age
50 years and over
People
50
Run by
Technical University of Munich
See details and how to joinNCT06796582
Phase 2Taking people
A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial Fibrillation
Where
Altenburg, Bad Oeynhausen, Bonn, Hanover
Age
18 years to 85 years
People
360 worldwide
Run by
Bayer
See details and how to joinNCT07625215 · EU 2025-523807-31-00
No phaseTaking people
PulseSelect™ PFA Global Registry
Where
Frankfurt, Heidelberg, Ludwigshafen am Rhein, Paderborn
Age
18 years and over
People
1,950 worldwide
Run by
Medtronic Cardiac Ablation Solutions
See details and how to joinNCT06393920
Phase 2Taking people
A study to investigate the efficacy, safety, tolerability and pharmacokinetics of PKN605 in participants with atrial fibrillation
Where
Bad Homburg, Berlin, Hamburg
Age
18 years and over
People
41 worldwide
Run by
Novartis Pharma AG
See details and how to join2025-520518-79-00 · EU 2025-520518-79-00
No phaseTaking people
PULSed Field Ablation for Atrial Fibrillation Using a Balloon for Early Intervention - Study
Where
Bad Oeynhausen, Cologne, Düsseldorf, Frankfurt, Giessen, Hamburg, Herne, Leipzig, Neuss, Nuremberg
Age
18 years and over
People
264
Run by
Asklepios proresearch
See details and how to joinNCT07621003
No phaseTaking people
Left-atrial Fibrosis in Persistent Atrial Fibrillation and Its Comorbidities
Where
Augsburg
Age
18 years and over
People
200
Run by
Christina Berr. MD
See details and how to joinNCT07857044
Phase 2Taking people
Clinical Phase 2 Trial of AP31969 Versus Placebo for Rhythm Control of Atrial Fibrillation
Where
Coburg, Frankfurt Am Main, Hamburg
Age
18 years and over
People
200 worldwide
Run by
Acesion Pharma
See details and how to joinNCT07267949 · EU 2025-521377-14-00
No phaseTaking people
Left Bundle Branch Area Pacing (LBBAP) PMCF Study
Where
Bad Nauheim
Age
18 years and over
People
200 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT07217392
No phaseTaking people
The Fourth Left Atrial Appendage Occlusion Study
Where
Bad Oeynhausen, Berlin, Cologne, Darmstadt, Erfurt, Frankfurt am Main, Frankfurt Am Main, Hamburg, Heidelberg, Kaiserslautern, Karlsruhe, Leipzig, Lübeck, Rostock, Zwickau
Age
18 years and over
People
4,000 worldwide
Run by
Hamilton Health Sciences Corporation
See details and how to joinNCT05963698
No phaseTaking people
AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure
Where
Munich
Age
18 years to 99 years
People
40
Run by
Technical University of Munich
See details and how to joinNCT06650995
Phase 3Taking people
The Direct Oral Anticoagulation versus Vitamin K Antagonist after Cardiac Surgery (DANCE) Trial
Where
Bonn, Essen, Freiburg, Hamburg, Jena, Leipzig
Age
18 years and over
People
1,000
Run by
Hamilton Health Sciences Corporation
See details and how to joinNCT04284839 · EU 2023-504504-28-00
No phaseNot yet taking people in Germany
Catheter Ablation for AF in Patients With Severe Mitral Regurgitation After Successful Transcatheter Mitral-Valve Repair
Where
Cologne, Frankfurt, Hamburg, Münster
Age
18 years and over
People
956
Run by
Atrial Fibrillation Network
See details and how to joinNCT07380932
No phaseNot yet taking people in Germany
Single-Shot Versus Focal Dual-Energy Pulsed Field-Based Ablation for Atrial Fibrillation
Where
Herne
Age
18 years and over
People
268
Run by
Marien Hospital Herne
See details and how to joinNCT07783919
No phaseNot yet taking people in Germany
Augmented Reality Aided Remote Access and Technical Support for Complex Ablation Procedures
Where
Lübeck
Age
18 years and over
People
60
Run by
University of Luebeck
See details and how to joinNCT07777042
No phaseTaking people
Comparison of LAA-Closure vs Oral Anticoagulation in Patients With NVAF and Status Post Intracranial Bleeding.
Where
Bad Neustadt an der Saale, Berlin, Bielefeld, Brandenburg an der Havel, Burgau, Chemnitz, Coburg, Dortmund, Dresden, Erfurt, Erlangen, Frankfurt am Main, Halle, Hamburg, Ingolstadt, Jena, Kaiserslautern, Koblenz, Leipzig, Lübeck, Magdeburg, Mannheim, Pirna, Recklinghausen, Rosenheim, Rotenburg an der Fulda, Rüsselsheim am Main, Zwickau
Age
18 years and over
People
530 worldwide
Run by
Jena University Hospital
See details and how to joinNCT04298723
No phaseTaking people
The DefiPace Study
Where
Dresden, Erlangen, Freiburg im Breisgau, Hanover, Jena, Nuremberg, Oldenburg, Ulm, Würzburg
Age
18 years and over
People
450 worldwide
Run by
Institut für Pharmakologie und Präventive Medizin
See details and how to joinNCT04804748
Phase 3Taking people
Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)
Where
Altenburg, Berlin, Dresden, Hamburg, Hanover, Konstanz, Ludwigshafen am Rhein, Ludwigshafen Am Rhein, Mainz, Markkleeberg, Paderborn, Schwerin
Age
65 years and over
People
2,500 worldwide
Run by
Anthos Therapeutics, Inc.
See details and how to joinNCT05712200 · EU 2023-503224-66-00
Phase 2Taking people
Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients
Where
Augsburg, Berlin, Bonn, Göttingen, Hamburg, Kiel, Mainz, Münster, Rostock, Stuttgart
Age
18 years and over
People
550
Run by
GCP-Service International West GmbH
See details and how to joinNCT06279793