Frontlight ResearchEarly access
Taking people in United StatesNo phase
Myriad used in surgery to rebuild soft tissue after wounds and infections
Follows safety and outcomes of Myriad in adults having soft tissue reconstruction surgery.
Key facts
- Who runs it
- Aroa Biosurgery Limited
- Where
- Baltimore, Columbus, Fort Myers, Gainesville, Greensboro, Iowa City, Lancaster, Los Angeles, Milwaukee, New Orleans, Pensacola, Phoenix, Poughkeepsie, and West Reading, United StatesSee the 15 sites
- Trial code
- Registry title
- Myriad™ Augmented Soft Tissue Reconstruction Registry
- Status
- Recruiting
- People taking part
- 800 people, planned
- Started
- 10 Jan 2022
- Expected to end
- Jan 2029
- Type of study
- Observational
- Treatments tested
- Myriad Matrix™ and Myriad Morcells™
- Record updated
- 15 July 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults having surgery to rebuild soft tissue, where the surgeon uses Myriad Matrix and/or Myriad Morcells. It observes safety and results.
- Age
- 18 years or older
- Sex
- Male and female
- Disease stage
- Soft tissue wounds needing reconstruction surgery, such as wounds that reopened after abdominal surgery, severe soft tissue infection, leg wounds, pilonidal sinus, anal fistula, hidradenitis suppurativa or pressure injuries.
- Earlier treatment
- Matrix and/or Morcells must be used in the person's soft tissue reconstruction surgery.
Main reasons for not taking part
- Known sensitivity to material from sheep
- Full thickness (third degree) burns
- Wounds with infection that is not under control (CDC Contamination Grade=4)
- Taking part in another clinical study now or in the past 30 days
- Pregnant or breastfeeding women
The registry criteria, word for word
Show all 11 criteriaShow less
Who can take part
- Willing and able to provide written informed consent and to comply with the requirements of Clinical Investigational Plan
- Male or female patients aged 18 years or above
- Patients where Matrix and/or Morcells were used as part of their soft tissue reconstruction procedure
- Subject that are willing and able to comply with all aspects of the treatment and evaluation schedule
Who cannot take part
- Patient is currently participating or has participated in another clinical study within past 30 days prior to enrollment
- Patients with wounds with uncontrolled clinical infection (CDC Contamination Grade=4)
- Any medical condition or serious intercurrent illness that, in the opinion of the investigator, may make it undesirable for the patient to participate in the study
- Patients with known sensitivity to ovine (sheep) derived material
- Patients with full thickness ('third degree') burns
- Pregnant or lactating women
- Any subject who, at the discretion of the Investigator, is not suitable for inclusion in the study
Where in United States
- Sinai Hospital of BaltimoreBaltimore, United StatesContact: Research CoordinatorTaking people
- Ohio State University Wexner Medical CenterColumbus, United StatesContact: Barnaby May, PhDEnrolling by invitation
- Associates in Medicine & SurgeryFort Myers, United StatesContact: Barnaby May, PhDNo longer taking part
- Northeast Georgia Medical Center, Inc.Gainesville, United StatesContact: Emily MurdochTaking people
- Moses H Cone Memorial Hospital Operating CorporationGreensboro, United StatesContact: Barnaby May, PhDNo longer taking part
- University of Iowa Health CareIowa City, United StatesContact: Barnaby May, PhDEnrolling by invitation
- Lancaster General HospitalLancaster, United StatesContact: Medoza AmeenTaking people
- Surgery Group LALos Angeles, United StatesContact: Barnaby May, PhDNo longer taking part
- The Medical College of WisconsinMilwaukee, United StatesContact: Thomas Carver, MDTaking people
- Ochsner Baptist Medical CenterNew Orleans, United StatesContact: Barnaby May, PhDEnrolling by invitation
- University Medical CenterNew Orleans, United StatesContact: Alison Smith, MD, PhDTaking people
- Asencion Sacred HeartPensacola, United StatesContact: Kymberly PalmerTaking people
- The Diane & Bruce Halle Arizona Burn Center at Valleywise HealthPhoenix, United StatesContact: Barnaby May, PhDEnrolling by invitation
- Nuvance Health Vassar Brothers Medical CenterPoughkeepsie, United StatesContact: Barnaby May, PhDEnrolling by invitation
- Tower Health Reading HospitalWest Reading, United StatesContact: Barnaby May, PhDEnrolling by invitation
About the trial
What the trial wants to find out
This is an observational study designed to evaluate the safety and clinical outcomes of Myriad™ in soft tissue reconstruction procedures. The study will enroll participants who are undergoing a surgical procedure, where the attending physician will use Myriad™ as part of the surgical intervention.
The group in the trial
- Myriad™
Ovine forestomach matrix sheet graft and morselized extracellular matrix
Treatment: Myriad Matrix™ and Myriad Morcells™
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Registry of Myriad™ Utilization in Soft Tissue Reconstruction Procedures
- Plain-language title
- Myriad used in surgery to rebuild soft tissue after wounds and infectionsGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 14 November 2026.
- Publications
- Record updated
- 15 July 2026