Hidradenitis suppurativa trials in United States

In United States 36 Also abroad 72

36 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Efficacy and Safety of Olatorepatide Versus Placebo in Adults With Moderate to Severe Hidradenitis Suppurativa Living With Overweight or Obesity
Where
The Bronx
Age
18 years and over
People
300
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07830329 · EU 2026-526375-39-00
Phase 1Taking people
A Study to Explore the Tissue Level Effects of Remibrutinib in Adults With Moderate to Severe HS
Where
Mayfield Heights, San Diego
Age
18 years to 65 years
People
30
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07855276 · EU 2025-524222-18-00
Phase 3Taking people
An Extension Study to Assess Safety and Efficacy of Remibrutinib in Participants With Moderate to Severe HS
Where
Birmingham, Boardman, Charleston, Fort Smith, Fremont, Glenview, Huntersville, Los Angeles, Mayfield Heights, Miami, New Albany, New York, North Little Rock, Omaha, Pittsburgh, Rochester, San Antonio, Sylmar, Tampa, Thousand Oaks, Troy, Vienna, Webster, West Dundee
Age
18 years to 100 years
People
710 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07665437 · EU 2025-523259-72-00
Phase 2Taking people
A Study to Investigate Efficacy and Safety of Duvakitug in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
Where
Birmingham, Miami
Age
18 years and over
People
156 worldwide
Run by
Sanofi
See details and how to joinNCT07812116
Phase 3Taking people
Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib
Where
Albuquerque, Ann Arbor, Auburn Hills, Baltimore, Baton Rouge, Bellaire, Bexley, Birmingham, Boca Raton, Boston, Brighton, Chapel Hill, Chicago, Cincinnati, Columbus, Coral Gables, Cumming, Dallas, Danville, Detroit, Dublin, East Syracuse, Fountain Valley, Fremont, Glenn Dale, Hialeah, Hollywood, Huntington Beach, Indianapolis, Irvine, Laguna Niguel, Los Angeles, Marietta, Miami, Miami Lakes, Mill Creek, Minneapolis, Missoula, Montgomery, New Orleans, New York, Norfolk, North Miami Beach, Northridge, Oakland, Ocala, Oklahoma City, Philadelphia, Phoenix, Plano, Plymouth Meeting, Portsmouth, Richmond, Rochester, Rockville, Saint Joseph, San Antonio, Sandy Springs, Santa Monica, Seattle, Sherman Oaks, Skokie, South Jordan, Spokane, St Louis, Stonecrest, Sunnyvale, Tampa, Troy, Tucson, Waterford, Webster, West Dundee, West Lafayette, West Palm Beach
Age
18 years and over
People
600 worldwide
Run by
Incyte Corporation
See details and how to joinNCT06855498 · EU 2024-520107-12-00
Phase 2Taking people
ORKA-002 Versus Placebo in Participants With Moderate-to-Severe Hidradenitis Suppurativa
Where
Baton Rouge, Birmingham, Canton, Chapel Hill, Chicago, Cromwell, Dallas, Fountain Valley, Los Angeles, Missouri City, New Brighton, New Orleans, New York, Omaha, Plainfield, Portland, San Antonio, Sandy Springs, Smyrna, St Louis
Age
18 years to 79 years
People
200 worldwide
Run by
Oruka Therapeutics, Inc.
See details and how to joinNCT07783542
Phase 2Taking people
A Study of SPY072 in Adults With Moderate to Severe Hidradenitis Suppurativa (The SKYLIGHT Trial)
Where
Atlanta, Baton Rouge, Birmingham, Boston, Bowling Green, Coral Gables, Detroit, Durham, Indianapolis, Irvine, Las Vegas, Mill Creek, Mt. Pleasant, Murray, Nashville, New York, Oklahoma City, Owensboro, Prosper, Rogers, Smyrna, The Bronx, Tyler
Age
18 years to 75 years
People
150 worldwide
Run by
Spyre Therapeutics, Inc.
See details and how to joinNCT07766005
Phase 2Taking people
A Study to Investigate Efficacy and Safety With SAR445399 in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
Where
Boston, Boynton Beach, Cumming, Evansville, Fayetteville, Fort Lauderdale, Fort Myers, Hollywood, Kansas City, Louisville, Miami, Norfolk, North Hollywood, Scottsdale, Skokie, Tampa, The Bronx, The Woodlands, Tulsa
Age
18 years and over
People
144 worldwide
Run by
Sanofi
See details and how to joinNCT07225569 · EU 2025-522695-83-00
Phase 1Taking people
Safety and Efficacy of Soquelitinib in Adults With Hidradenitis Suppurativa
Where
Boston, Bowling Green, Camp Hill, Fargo, Mayfield Heights, Nashville, New York, Owensboro, Philadelphia, The Bronx, West Lafayette
Age
18 years and over
People
25
Run by
Corvus Pharmaceuticals, Inc.
See details and how to joinNCT07828860
Phase 2Taking people
Brivekimig for the Treatment of Moderate to Severe Hidradenitis Suppurativa
Where
Atlanta, Baton Rouge, Chapel Hill, Dallas, Fort Myers, Johnston, Las Vegas, Miami, Miramar, Myrtle Beach, New York, Northridge, Phoenix, Savannah, Scottsdale, St Louis, West Des Moines
Age
18 years and over
People
208 worldwide
Run by
Sanofi
See details and how to joinNCT07170917 · EU 2025-522333-61-00
Phase 2Taking people
Safety and Efficacy of Roflumilast Foam 0.3% in Adolescent and Adult Subjects With Hidradenitis Suppurativa
Where
Missouri City
Age
12 years and over
People
10
Run by
Harrison Dermatology
See details and how to joinNCT07689188
Phase 1Taking people
Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa
Where
Baton Rouge, Bolivar, Bowling Green, Castle Rock, Columbus, Fargo, Fountain Valley, New York, Northridge, Oklahoma City, Orange, Philadelphia, Phoenix, Sanford, Sweetwater, Tampa, Thousand Oaks, Troy, West Lafayette
Age
12 years to 75 years
People
24
Run by
Incyte Corporation
See details and how to joinNCT07049575
Phase 2Taking people
Pharmacokinetics, Safety, and Efficacy of Povorcitinib in Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa
Where
Albuquerque, Auburn Hills, Baltimore, Bellaire, Birmingham, Boston, Bowling Green, Dallas, Danville, Detroit, El Paso, Farmington, Gambrills, Kansas City, Leawood, Miami, Missoula, Phoenix, Sandy Springs, Skokie, South Jordan, St Louis, Tampa, Troy
Age
12 years to 17 years
People
40 worldwide
Run by
Incyte Corporation
See details and how to joinNCT07213973
No phaseTaking people
Regulation of Inflammatory Genes in Hidradenitis Suppurativa
Where
Birmingham
Age
18 years to 89 years
People
200
Run by
University of Alabama at Birmingham
See details and how to joinNCT05507125
Phase 1Taking people
A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)
Where
Boston, Chapel Hill, Durham, Milwaukee, Santa Monica, South Miami
Age
18 years and over
People
20 worldwide
Run by
UCB Biopharma SRL
See details and how to joinNCT06888193 · EU 2024-518689-29-00
No phaseTaking people
Targeting Nociceptors in Hidradenitis Suppurativa
Where
Worcester
Age
18 years to 75 years
People
20
Run by
University of Massachusetts, Worcester
See details and how to joinNCT05403710
No phaseNot yet taking people in United States
An Observational Study of Patients With Dermatologic Disease
Where
New York
People
2,000,000
Run by
Target PharmaSolutions, Inc.
See details and how to joinNCT07748169
Phase 2Not yet taking people in United States
Botulinum Toxin Blockade of Neuronal Signals to Immune Cells as a Novel Treatment for Hidradenitis Suppurativa
Where
Worcester
Age
13 years to 75 years
People
40
Run by
University of Massachusetts, Worcester
See details and how to joinNCT07756346
Early phase 1Taking people
Capsule Microbiota Transplant Therapy for Hidradenitis Suppurativa
Where
Minneapolis
Age
18 years and over
People
16
Run by
University of Minnesota
See details and how to joinNCT06058520
No phaseNot yet taking people in United States
Mediterranean Dietary Intervention for HS
Where
Chapel Hill
Age
18 years and over
People
30
Run by
University of North Carolina, Chapel Hill
See details and how to joinNCT07800416
Early phase 1Taking people
Evaluate the Safety and Efficacy of Subcutaneous Siplizumab in the Treatment of Hidradenitis Suppurativa.
Where
Birmingham
Age
18 years and over
People
12
Run by
University of Alabama at Birmingham
See details and how to joinNCT06326476
Phase 2Taking people
A Study to Assess NAV-240 in Adult Participants With Hidradenitis Suppurativa
Where
Boston, Maitland, Miami, Murray, North Miami Beach, Phoenix, Portsmouth, Ridgeland, Scottsdale, Tamarac, Tampa, The Bronx
Age
18 years to 70 years
People
150 worldwide
Run by
Navigator Medicines, Inc.
See details and how to joinNCT07384975 · EU 2025-523557-33-00
No phaseTaking people
Myriad™ Augmented Soft Tissue Reconstruction Registry
Where
Baltimore, Columbus, Fort Myers, Gainesville, Greensboro, Iowa City, Lancaster, Los Angeles, Milwaukee, New Orleans, Pensacola, Phoenix, Poughkeepsie, West Reading
Age
18 years and over
People
800
Run by
Aroa Biosurgery Limited
See details and how to joinNCT05243966
Phase 2Taking people
The Safety and Efficacy of Roflumilast Foam in HS
Where
Boston
Age
18 years and over
People
20
Run by
Beth Israel Deaconess Medical Center
See details and how to joinNCT07263230
Phase 3Enrolling by invitation
A Study to Evaluate the Long-term Safety, Tolerability, and Efficacy of Subcutaneous Sonelokimab in Participants With Moderate to Severe Hidradenitis Suppurativa
Where
Ann Arbor, Aventura, Birmingham, Boardman, Boston, Canton, Clarkston, Columbus, Coral Gables, Dallas, Dayton, Fargo, Hialeah, Hollywood, Houston, Las Vegas, Los Angeles, Louisville, Macon, Metairie, Miami, Mill Creek, Morgantown, Murfreesboro, Murray, New Albany, New Brighton, New York, North Little Rock, Northridge, Ocala, Oklahoma City, Omaha, Plainfield, San Antonio, Sandy Springs, Skokie, South Jordan, Tampa, The Bronx, Waterford, West Dundee
Age
12 years and over
People
835 worldwide
Run by
MoonLake Immunotherapeutics AG
See details and how to joinNCT07007637