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Testing New Brain Electrodes to Locate Seizure Origins in Drug-Resistant Epilepsy

Tests tiny brain electrodes to find the area causing seizures in people with hard-to-treat epilepsy.

Plain-language title generated from the registry record
Registry title: Using Micro-filaments to Detect "fast Ripples" and Improve the Identification of the Epileptogenic Zone

Key facts

Where
Montreal, CanadaSee the site

Where in Canada

  • McGill UniversityMontreal, CanadaTaking people

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Trial details

Who runs it
Adrien Peyrache
Trial code
NCT05254730
Record updated
20 November 2024
Original description
record fast ripples with novel intracranial electrodes with micro-tetrodes to improve the identification of epileptogenic zone (EZ) and investigate the neuronal circuits underlying brain dynamics associated with epilepsyRead full original descriptionShow less

Using Micro-filaments to Detect "fast Ripples" and Improve the Identification of the Epileptogenic Zone

record fast ripples with novel intracranial electrodes with micro-tetrodes to improve the identification of epileptogenic zone (EZ) and investigate the neuronal circuits underlying brain dynamics associated with epilepsy

Inclusion: inclusion criteria is determined based on the clinical diagnosis of the refractory epilepsy and the admissibility of the patient for the stereoelectroencephalography (sEEG) procedure.

Exclusion: severe psychiatric disorders,; contraindication for performing an MRI: claustrophobia, a cardiac or neural stimulator, ferromagnetic surgical clips, cochlear implants, intraocular metallic foreign body or in the nervous system,; contraindication to intracerebral investigation (macro-electrodes): ongoing infection, severe associated pathology (cardiac, pulmonary, renal, hepatic), pregnant or nursing women,; severe agitation during their crisis; anti thrombotic ongoing treatment.

ClinicalTrials.gov NCT05254730