Epilepsy trials in Canada

In Canada 22 Also abroad 452

22 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures
Where
Lethbridge, London, Montreal, Vancouver
Age
12 years and over
People
160 worldwide
Run by
Xenon Pharmaceuticals Inc.
See details and how to joinNCT05667142 · EU 2022-502286-16-00
Phase 3Enrolling by invitation
An Open-label Study of XEN1101 in Epilepsy
Where
Lethbridge, London, Montreal
Age
12 years and over
People
880 worldwide
Run by
Xenon Pharmaceuticals Inc.
See details and how to joinNCT05718817 · EU 2022-502282-24-00
Phase 1/2Taking people
ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet Syndrome
Where
Montreal
Age
2 years to 12 years
People
32 worldwide
Run by
Ionis Pharmaceuticals, Inc.
See details and how to joinNCT07531745
Phase 3Taking people
A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome
Where
Ottawa, Toronto, Vancouver
Age
2 years and over
People
150 worldwide
Run by
Epygenix
See details and how to joinNCT04462770 · EU 2024-518628-57-00
No phaseTaking people
Artificial Intelligence for Brain MRI Analysis in Epilepsy
Where
Montreal
People
2,000 worldwide
Run by
Istituto Giannina Gaslini
See details and how to joinNCT07881185
Phase 3Enrolling by invitation
A Study to Investigate LP352 in Children and Adults With Developmental and Epileptic Encephalopathy (DEE)
Where
Toronto
Age
2 years to 66 years
People
324 worldwide
Run by
Longboard Pharmaceuticals
See details and how to joinNCT06908226 · EU 2024-514974-39-00
Phase 2Not yet taking people in Canada
Safety and Efficacy of AV078 in Participants With Tuberous Sclerosis Complex (TSC) Refractory Epilepsy (RESTOR-1)
Where
London
Age
12 years and over
People
42
Run by
Aeovian Pharmaceuticals, Inc.
See details and how to joinNCT07680322
Phase 4Not yet taking people in Canada
A Study to Investigate the Transition of Children From 'Artisanal" Cannabidiol (CBD) to Epidiolex
Where
Toronto
Age
2 years to 18 years
People
25
Run by
Elizabeth Donner
See details and how to joinNCT06924827
Phase 3Not yet taking people in Canada
COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE"
Where
London, Toronto
Age
2 years and over
People
438 worldwide
Run by
Yale University
See details and how to joinNCT07281027
No phaseTaking people
LIFUS For Neurological Disorders
Where
Toronto
Age
18 years to 85 years
People
50
Run by
University Health Network, Toronto
See details and how to joinNCT07417280
No phaseTaking people
Real-World Evidence in Patient-Reported Outcomes for Medical Cannabis (MC-RWE)
Where
Toronto
Age
19 years and over
People
1,000
Run by
University Health Network, Toronto
See details and how to joinNCT04526093
No phaseTaking people
The Genetics Navigator: Evaluating a Digital Platform for Genomics Health Services
Where
Toronto
Age
18 years and over
People
170
Run by
Unity Health Toronto
See details and how to joinNCT06455384
No phaseEnrolling by invitation
5-SENSE Score Validation Study
Where
Dalhousie, London
Age
15 years and over
People
400 worldwide
Run by
Duke University
See details and how to joinNCT06138808
Phase 2Taking people
Enhanced MRI Imaging in Healthy Participants and Participants With Epilepsy
Where
Edmonton
Age
18 years to 64 years
People
50
Run by
University of Alberta
See details and how to joinNCT06483061
No phaseTaking people
Clinical Outcomes of Pregnant Individuals With Epilepsy - Prospective Study
Where
Toronto
People
80
Run by
University Health Network, Toronto
See details and how to joinNCT05485649
No phaseTaking people
The Lullaby Project as a Musical Intervention for Pregnant Individuals With Epilepsy
Where
Toronto
Age
18 years and over
People
30
Run by
University Health Network, Toronto
See details and how to joinNCT05503290
No phaseTaking people
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
Where
Hamilton
People
1,000 worldwide
Run by
Columbia University
See details and how to joinNCT01694940
No phaseTaking people
Biology of Juvenile Myoclonic Epilepsy
Where
Toronto
Age
10 years to 40 years
People
1,000 worldwide
Run by
King's College London
See details and how to joinNCT03400371
No phaseNot yet taking people in Canada
Deep Brain Stimulation vs. Vagus Nerve Stimulation for Epileptic Spasms
Where
Toronto
Age
5 years to 17 years
People
20
Run by
The Hospital for Sick Children
See details and how to joinNCT07010276
Phase 3Taking people
Lemborexant Treatment of Insomnia Linked to Epilepsy
Where
Winnipeg
Age
18 years and over
People
26 worldwide
Run by
University of Manitoba
See details and how to joinNCT06262594
No phaseTaking people
Using Micro-filaments to Detect "fast Ripples" and Improve the Identification of the Epileptogenic Zone
Where
Montreal
People
45
Run by
Adrien Peyrache
See details and how to joinNCT05254730
No phaseTaking people
Real World Evidence on the Use of Medical Cannabis in Pediatrics
Where
Winnipeg
Age
3 years to 17 years
People
500
Run by
University of Manitoba
See details and how to joinNCT05863910