Tests a diabetes prevention program adapted for underserved African Americans

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for Black or African American adults who are overweight and have prediabetes or a high risk of diabetes. It tests diabetes prevention programs.

Age

18 years or older

Sex

All sexes can join

Disease stage

Overweight (BMI above 24) and prediabetes, or earlier gestational diabetes, or a high-risk result on a prediabetes risk test

Earlier treatment

Cannot be in a weight loss program now, and cannot have had weight loss (bariatric) surgery in the last year

Main reasons for not taking part

• Diagnosed with diabetes
• Pregnant, planning pregnancy in the next year, breastfeeding, or gave birth in the last 6 months
• Not fluent in English
• Had heart failure
• Not willing to use a fitness tracker, wi-fi scale and the internet

The registry criteria, word for word

What the trial wants to find out

African Americans (AAs) have rates of diabetes mellitus (DM) twice that of Whites and are disproportionately affected by leading risk factors for DM - obesity and low-income. A critical strategy in the battle against DM is the Diabetes Prevention Program (DPP), an evidence-based intervention that significantly delays or prevents Type 2 diabetes through the promotion of diet change, exercise and modest weight loss. However, weight loss from the DPP among AAs is about half that of White participants, and suboptimal AA attendance is a critical contributor. The investigators propose to conduct a study that will address social determinants (SD) that challenge DPP attendance with underserved African Americans from a safety net hospital. The investigators will examine DPP attendance and weight loss with participants randomized to 3 groups: standard DPP, a culturally-tailored DPP to address acceptability, and a culturally-tailored DPP enhanced to address socioeconomic-related barriers to DPP participation. This novel study is the first to tailor the DPP to address SD cultural and socioeconomic barriers that limit DPP attendance and reduce its effectiveness on outcomes. The proposed multidimensional, SD tailored DPP has great potential to be a feasible and scalable model to reduce DM risks among urban, African Americans and ultimately reduce DM disparities.

The 3 groups in the trial

• StandardExisting treatment, for comparison

  Standard Diabetes Prevention Program (DPP)

  Treatment: Diabetes Prevention Program

• Culturally Tailored DPPTreatment being tested

  DPP culturally tailored for African Americans

  Treatment: Culturally Tailored Diabetes Prevention Program and Diabetes Prevention Program

• Culturally Tailored DPP Enhanced with Socioeconomic SupportsTreatment being tested

  Culturally tailored DPP plus promotions for class attendance, hybrid attendance (in-person and virtual), and linkage to care services provided by a community health worker

  Treatment: Culturally Tailored Diabetes Prevention Program, Culturally Tailored DPP Enhanced with Socioeconomic Supports, and Diabetes Prevention Program