Frontlight ResearchEarly access
TerminatedPhase 1
Study of the Safety and Feasibility of Psilocybin in Adults With Methamphetamine Use Disorder
Key facts
- Who runs it
- University of Wisconsin, Madison
- Where
- Madison, United StatesSee the site
- Trial code
- Status
- Terminated
- Phase
- Phase 1
- People taking part
- 5 people enrolled
- Started
- 3 Mar 2023
- Ended
- 7 Mar 2024
- Type of study
- Interventional
- Treatments tested
- Psilocybin
- Record updated
- 12 May 2026
- Why it stopped
- due to sponsor financial constraints
Who can take part
- Age
- 25 years to 65 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- Diagnosis of methamphetamine use disorder
Who cannot take part
- Current use of and inability or unwillingness to taper off of medications that may interact with psilocybin
- Inadequately treated hypertension, defined as 2 blood pressure readings, 10 minutes apart, of greater than 140/90 mmHg systolic/diastolic
- Current acute coronary syndrome or angina
- History of heart transplant or stroke
- Current insulin dependence, due to Type I or Type II diabetes
- Positive urine pregnancy at any time point during screening or study participation
Where in United States
- University of WisconsinMadison, United States
About the trial
What the trial wants to find out
The purpose of this research study is to investigate the safety and feasibility of two (2) oral doses of psilocybin when combined with behavioral support for methamphetamine use disorder (MUD). Participants have a diagnosis of methamphetamine use disorder (MUD). Participants can expect to be actively engaged in the study for up to 26 weeks.
The group in the trial
- Oral PsilocybinTreatment being tested
Psilocybin with psychological support: Psilocybin will be administered in the form of capsules, taken orally with water. Each participant will receive 2 doses, approximately 4 weeks apart.
Treatment: Psilocybin
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Safety and Feasibility of Psilocybin in Methamphetamine Use Disorder in a Community-Based Sample
- Record updated
- 12 May 2026