Cocaine and methamphetamine use disorder trials in United States

In United States 45 Also abroad 65

45 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Continuum of Care in Hospitalized Patients With Opioid/Stimulant Use Disorder and Infectious Complications From Drug Use
Where
Atlanta, Baltimore, Morgantown, Washington D.C.
Age
18 years and over
People
304
Run by
Elana Rosenthal
See details and how to joinNCT06513156
Phase 1Not yet taking people in United States
Low Intensity Focused Ultrasound in Cocaine Use Disorder
Where
Philadelphia
Age
18 years to 65 years
People
20
Run by
University of Pennsylvania
See details and how to joinNCT07928648
Phase 2Taking people
Psilocybin Therapy for Methamphetamine Use Disorder and HIV
Where
San Francisco
Age
25 years to 64 years
People
30
Run by
Nicky Mehtani, MD, MPH
See details and how to joinNCT07756736
No phaseTaking people
Rehabilitation Program for People With Methamphetamine-Associated Cardiopulmonary Conditions
Where
Salt Lake City
Age
18 years and over
People
45
Run by
Michael Incze
See details and how to joinNCT07915882
No phaseTaking people
rTMS and Cognitive-behavioral Therapy for Cocaine Use Disorder
Where
New York
Age
22 years to 65 years
People
30
Run by
New York State Psychiatric Institute
See details and how to joinNCT05974202
No phaseNot yet taking people in United States
Remote Intervention to Prevent Overdose
Where
Birmingham
Age
18 years and over
People
100
Run by
University of Alabama at Birmingham
See details and how to joinNCT07128485
No phaseNot yet taking people in United States
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
Where
Richmond
Age
17 years to 99 years
People
1,000,000
Run by
Veterans Recovery Network Inc.
See details and how to joinNCT07661823
No phaseEnrolling by invitation
PATH to Reducing Burnout Among Peers Who Deliver Overdose Prevention Services (R33 Phase Clinical Trial)
Where
Chicago
Age
18 years and over
People
200
Run by
Chestnut Health Systems
See details and how to joinNCT07886944
Phase 2Taking people
Randomized Controlled Trial of Tirzepatide for Methamphetamine Use Disorder
Where
Dallas, Los Angeles, San Francisco, Tulsa
Age
18 years to 65 years
People
228
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT07825857
No phaseTaking people
Transcranial Direct Current Stimulation (tDCS) for Treatment of Substance Use Disorder
Where
New York
Age
18 years to 60 years
People
240
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT07318480
No phaseNot yet taking people in United States
Examination of Transcranial Focused Ultrasound on Brain Activity in Adults With Cocaine Use Disorder
Where
Pittsburgh
Age
18 years to 45 years
People
57
Run by
Mary Phillips, MD MD (Cantab)
See details and how to joinNCT07852923
No phaseTaking people
Open-label Feasibility Trial of HD-tDCS During Cognitive Behavioral Therapy for Cocaine Use Disorder
Where
Richmond
Age
18 years to 65 years
People
36
Run by
Virginia Commonwealth University
See details and how to joinNCT07829263
No phaseTaking people
rTMS for Craving in Methamphetamine Use Disorder
Where
Portland
Age
18 years to 65 years
People
50
Run by
Oregon Health and Science University
See details and how to joinNCT03470480
Phase 2Not yet taking people in United States
Psilocybin for Methamphetamine Use Disorder
Where
Birmingham
Age
18 years and over
People
42
Run by
Peter Hendricks
See details and how to joinNCT07774702
No phaseTaking people
Kentucky Women's Justice Community Overdose Innovation Network - Phase II
Where
Barbourville, Harlan, Hyden
Age
18 years and over
People
300
Run by
Michele Staton
See details and how to joinNCT07179614
Early phase 1Taking people
Imaging Mitochondrial Complex-I in Cocaine Use Disorder: a [F-18]BCPP-EF PET Study
Where
Pittsburgh
Age
18 years to 45 years
People
40
Run by
Rajesh Narendran
See details and how to joinNCT07773649
No phaseTaking people
Repetitive Transcranial Magnetic Stimulation Treatment of Stimulant Use Disorder
Where
Palo Alto
Age
18 years to 65 years
People
106
Run by
VA Office of Research and Development
See details and how to joinNCT07112105
Phase 1Taking people
Optimizing Transcranial Magnetic Stimulation for Stimulant Use Disorder
Where
Minneapolis
Age
18 years and over
People
50
Run by
University of Minnesota
See details and how to joinNCT06790576
Phase 1Taking people
Safety Study of a Disrupted Adenovirus (Ad) Serotype Cocaine Vaccine for Cocaine-dependent Individuals
Where
New York
Age
21 years to 69 years
People
150
Run by
Weill Medical College of Cornell University
See details and how to joinNCT02455479
No phaseTaking people
CHAMPION: Combining HIV And Meth Prevention and Treatment Interventions Optimized for HIV-Negative MSM
Where
San Francisco
Age
18 years to 40 years
People
100
Run by
University of California, San Diego
See details and how to joinNCT07213258
Phase 1/2Taking people
The Impact of Cobenfy Maintenance on Cocaine's Effects
Where
Lexington
Age
18 years to 60 years
People
32
Run by
Joshua A. Lile, Ph.D.
See details and how to joinNCT07624227
No phaseTaking people
reSET for the Treatment of Stimulant Use in HIV Clinics: Care Optimization Supporting Treatment Adherence (COSTA)
Where
Miami
Age
18 years to 90 years
People
260
Run by
University of Miami
See details and how to joinNCT05958017
No phaseNot yet taking people in United States
Culturally Adapted Contingency Management
Where
New Haven
Age
18 years to 65 years
People
70
Run by
Yale University
See details and how to joinNCT07443332
Early phase 1Taking people
Imaging CRF X NOP Interactions in CUD
Where
Pittsburgh
Age
18 years to 55 years
People
80
Run by
Rajesh Narendran
See details and how to joinNCT05008146
Early phase 1Taking people
[C-11]NPA PET-amphetamine in Cocaine Use Disorders
Where
Pittsburgh
Age
18 years to 55 years
People
30
Run by
Rajesh Narendran
See details and how to joinNCT05011760