Testing mitoquinone for long-term effects of COVID-19 in adults
Tests the supplement mitoquinone against placebo in adults recovering from COVID-19.
Plain-language title generated from the registry record
Registry title: Long-term COVID and Rehabilitation
Key facts
- Where
- Salt Lake City, United StatesSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who had COVID-19 3 to 12 months ago, including people with long-COVID, to test rehabilitation and a supplement for blood vessel health.
- Age
- 18 years and older
- Sex
- All sexes can join.
- Disease stage
- Long-COVID, or recovered from COVID-19, 3 to 12 months after the first COVID-19 diagnosis.
- Earlier treatment
- People already taking Mito-Q, or unwilling to stop dietary supplements, cannot join.
- Biomarker or test result
- A positive SARS-CoV-19 test near the time of the COVID-19 diagnosis.
Main reasons for not taking part
- BMI above 45 kg/m2
- Severe or unstable heart, artery, brain blood vessel or lung disease, or uncontrolled high blood pressure
- Kidney disease needing dialysis or severe kidney problems
- Alzheimer's disease or dementia
- Current smokers, or people who stopped smoking in the last 10 years
Read by machine on 12 November 2026.
Where in United States
- VA Salt Lake City Health Care System, Salt Lake City, UTSalt Lake City, United StatesContact: P Jon White, MDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- VA Office of Research and Development
- Trial code
- NCT05373043
- Record updated
- 30 July 2026
- Original description
The proposed focuses on improving both morbidity and mortality in older Veterans and those recovering from COVID-19 by developing rehabilitation therapies to augment vascular endothelial function by combating the oxidative stress and inflammation associated with aging and further induced by COVID-19. The investigators expected outcomes will have an important positive impact because they will provide scientifically sound recommendations for rehabilitation to improve vascular endothelial function and minimize the long-term consequences of COVID-19.Read full original descriptionShow less
Evaluating the Long-term Health Consequences of COVID-19 and Rehabilitation Therapies to Speed Convalescence
The proposed focuses on improving both morbidity and mortality in older Veterans and those recovering from COVID-19 by developing rehabilitation therapies to augment vascular endothelial function by combating the oxidative stress and inflammation associated with aging and further induced by COVID-19. The investigators expected outcomes will have an important positive impact because they will provide scientifically sound recommendations for rehabilitation to improve vascular endothelial function and minimize the long-term consequences of COVID-19.
Inclusion: Long-COVID and COVID-recovered patients must have SARS-CoV-19 positive test near the time of COVID-19 diagnosis; Long-COVID and COVID-recovered patients must be 3-12 months post-initial COVID-19 diagnosis; Ability to sign informed consent.
Exclusion: Any other condition or event considered exclusionary by the PIs or a physician; Unstable (<6 months) or severe coronary artery disease (CAD-RADS score = 4A), peripheral artery disease (Ankle Brachial Index <0.40), cerebrovascular disease (identified by previous stroke in last 12 months), severe COPD (=Stage III), uncontrolled hypertension (>160/100 mmHg), chronic kidney disease requiring dialysis, severe renal insufficiency (creatinine clearance <30 by the Cockcroft-Gault formula), Alzheimer's disease, dementia; BMI >45 kg/m2; Orthopedic limitations that would prohibit exercise; Current smokers and individuals that stopped smoking in the last 10 years; Already taking Mito-Q or unwilling to cease dietary supplements for participation.