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Studies why some people develop heart failure with preserved ejection fraction

Collects information on adults with heart failure with preserved ejection fraction attending a clinic.

Plain-language title generated from the registry record
Registry title: Characteristics, Phenotypes, and TRAITS of Heart Failure With Preserved Ejection Fraction (TRAITS-HFpEF)

Key facts

Where
Manchester, United KingdomSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with heart failure with preserved ejection fraction (HFpEF) who attend the HFpEF clinic at MFT. Information from their clinic visits is collected routinely.

Age
18 years or older
Sex
All sexes can join
Disease stage
Heart failure with preserved ejection fraction (HFpEF), seen at the HFpEF clinic at MFT

Main reasons for not taking part

  • Under 18 years old
  • Imprisonment
  • Cannot give full written or verbal informed consent in English

Read by machine on 9 November 2026.

Where in United Kingdom

  • Manchester University NHS Foundation TrustManchester, United KingdomTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Manchester University NHS Foundation Trust
Trial code
NCT05383287
Record updated
1 October 2025
Original description
Heart failure with preserved ejection fraction (HFpEF), a certain type of heart failure, occurs when the heart doesn't pump blood around the body properly. It can cause breathlessness, tiredness, and swollen feet or ankles. It is not clear why people develop HFpEF and treatment options are very limited.Read full original descriptionShow less

Characteristics, Phenotypes, and TRAITS of Heart Failure With Preserved Ejection Fraction (TRAITS-HFpEF)

Heart failure with preserved ejection fraction (HFpEF), a certain type of heart failure, occurs when the heart doesn't pump blood around the body properly. It can cause breathlessness, tiredness, and swollen feet or ankles. It is not clear why people develop HFpEF and treatment options are very limited.

TRAITS-HFpEF is a study that aims to understand why people develop HFpEF, identify new tests and treatments, and gain information on the life expectancy of people living with this condition. It will do this by routinely collecting information on people attending a specialised outpatient HFpEF clinic.

Inclusion: Patients attending the HFpEF clinic at MFT.

Exclusion: Age < 18 years; Imprisonment; Inability to provide full written or verbal informed consent in English.

ClinicalTrials.gov NCT05383287