Studies brain activity linked to anxiety in people with epilepsy
Records brain activity during an anxiety-inducing task in adults with drug-resistant epilepsy.
Plain-language title generated from the registry record
Registry title: Electroclinical Correlation of Anxiety
Key facts
- Where
- Bordeaux, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT05393518, who can take part
Where in France
- CHU de BordeauxBordeaux, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Bordeaux
- Trial code
- NCT05393518
- Record updated
- 25 July 2025
- Original description
Anxiety disorders have the highest prevalence among mental disorders and cause considerable individual and financial costs. Current treatments do not relieve mental suffering of many patients. Understanding neurobiological mechanisms involved in pathological anxiety is a major scientific challenge.Read full original descriptionShow less
Electroclinical Correlation of Anxiety, Evidences From Intracerebral Recordings
Anxiety disorders have the highest prevalence among mental disorders and cause considerable individual and financial costs. Current treatments do not relieve mental suffering of many patients. Understanding neurobiological mechanisms involved in pathological anxiety is a major scientific challenge.
Inclusion: Man or woman; Aged 18 to 65; With drug-resistant epilepsy; Benefiting from a phase II pre-surgical assessment with intracerebral electrophysiological exploration by stereo-EEG; Meeting the DSM-5 diagnostic criteria for generalized anxiety disorder ("pathological" population) or not meeting the DSM-5 diagnostic criteria for generalized anxiety disorder ("control" population); WAIS IV full scale IQ > 75 or IAG > 81; Affiliate or beneficiary of a social security scheme; Giving free, informed consent in writing and signed by the participant and the investigator.
Exclusion: Suffer from a chronic delusional disorder (eg: schizophrenia); Have a moderate or high risk of suicide assessed using the corresponding section of the structured psychiatric interview called "Mini International Neuropsychiatric Interview" (M.I.N.I. 7.0) or a score > 2 on item 10 of the MADRS, assessing suicidal risk; Have severe and / or decompensated somatic illness other than drug-resistant epilepsy; Being unable to give personal consent; Be subject to a measure of legal protection (curatorship, guardianship) or placed under judicial protection; Being pregnant or breastfeeding.