Studying how the gut absorbs sugar to predict weight loss after surgery
Studies gut sugar absorption in adults with obesity considering bariatric surgery.
Plain-language title generated from the registry record
Registry title: Dietary Sugar Absorptive Phenotype for Prediction of Weight Loss Outcome
Key facts
- Where
- Jacksonville, United StatesSee the site
Where in United States
- Mayo Clinic FloridaJacksonville, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mayo Clinic
- Trial code
- NCT05408728
- Record updated
- 2 October 2026
- Original description
This study is trying to determine whether the success of bariatric surgery can be predicted by evaluating the dietary sugar absorptive characteristics in the small intestine and if there is any gene expression change on the dietary sugar absorptive characteristics.Read full original descriptionShow less
Dietary Sugar Hyper-absorptive Intestinal Phenotype as a Predictor of Weight Loss Post-bariatric Surgery
This study is trying to determine whether the success of bariatric surgery can be predicted by evaluating the dietary sugar absorptive characteristics in the small intestine and if there is any gene expression change on the dietary sugar absorptive characteristics.
Inclusion: Obese patients (BMI ≥ 30) scheduled for BS undergoing standard of care screening EGD, or lean BS-naïve individuals (BMI ≤ 25) subjected to EGD for routine clinical indications as part of standard care.
Exclusion: Pregnant women because endoscopy is a risk factor. All patients of childbearing age undergo history as well as urine pregnancy test as a standard of care prior to undergoing endoscopy as the procedure is performed under anesthesia; Using weight loss medications; Subjects with preexisting conditions (e.g., bleeding at the time of the procedure, suspected perforation during the standard-of-care procedure) will be excluded from the study at the time of the endoscopy; A history of surgery on the stomach or small intestine; Type 1 diabetes (clinical diagnosis and/or positive glutamic acid decarboxylase antibodies); Active malignancy within the last 5 years; Adults unable to consent, including non-English speakers; Prisoners; Have a contraindication to endoscopy.